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SolMER as a Biomarker for Cardiotoxicity? & Hidalgo Macrophages in the Heart?

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Release Date: 03/06/2024

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This episode explores the therapeutic potential of singing for cardiovascular health, highlighting its benefits on respiratory function, emotional well-being, and heart rate variability. It discusses the physiological responses to singing, comparable to moderate exercise, and emphasizes the need for further research to validate these findings. Join us as we delve into how singing could become a holistic approach to heart health. Baliga RR. Sing for a long and healthy life? Eur Heart J. 2024 Apr 12:ehad819. doi: 10.1093/eurheartj/ehad819. Epub ahead of print. PMID: 38607286. ...

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References:

Nicolás-Ávila JA,et al, Hidalgo A. A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart. Cell. 2020 Oct 1;183(1):94-109.e23. doi: 10.1016/j.cell.2020.08.031. Epub 2020 Sep 15. PMID: 32937105.
Bartelt A, Weber C. Mitochondrial Ejection for Cardiac Protection: The Macrophage Connection. Cell Metab. 2020 Oct 6;32(4):512-513. doi: 10.1016/j.cmet.2020.09.014. PMID: 33027673.
Bordon Y. Macrophages clean up to keep the heart pumping. Nat Rev Immunol. 2020 Nov;20(11):648-649. doi: 10.1038/s41577-020-00459-x. PMID: 32989291.
Burridge PW, Thorp EB. Doxorubicin-Induced Ascension of Resident Cardiac Macrophages. Circ Res. 2020 Aug 14;127(5):628-630. doi: 10.1161/CIRCRESAHA.120.317626. Epub 2020 Aug 13. PMID: 32790526; PMCID: PMC7430044.
Kolodgie FD, , Narula J. Targeting of apoptotic macrophages and experimental atheroma with radiolabeled annexin V: a technique with potential for noninvasive imaging of vulnerable plaque. Circulation. 2003 Dec 23;108(25):3134-9. doi: 10.1161/01.CIR.0000105761.00573.50. Epub 2003 Dec 15. PMID: 14676140.
McNally EM. Cardiac Macrophages - Keeping the Engine Running Clean. N Engl J Med. 2020 Dec 17;383(25):2474-2476. doi: 10.1056/NEJMcibr2030271. PMID: 33326720.
Zhang WY, Ebert AD, Narula J, Wu JC. Imaging cardiac stem cell therapy: translations to human clinical studies. J Cardiovasc Transl Res. 2011 Aug;4(4):514-22. doi: 10.1007/s12265-011-9281-3. Epub 2011 May 3. PMID: 21538182; PMCID: PMC3657500.