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Kunal Ghosh on the advantages of imaging tools for neuronal recordings & pattern recognition with Inscopix

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Release Date: 07/05/2021

Victor Pikov on starting a bioelectronic medicine company after working at Galvani show art Victor Pikov on starting a bioelectronic medicine company after working at Galvani

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is the founder and CEO of , a sacral nerve stimulation neuromodulation company and VP of Technology at TRI, Trans Stimulation Incorporated. He also worked at Galvani, a joint venture between Google and GSK as well as working in academia before.  Top 3 Takeaways "When you try to speak to potential investors who consider themselves experts in medical devices, they typically fall into three categories: One is no experience with neuromodulation and another bucket is experienced with wearable neuromodulation. And the third very small bucket is experience with implantable class three...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is at Stanford University. He has had many successful technologies spun off into companies or patents including those involving retinal prosthetics, optical imaging and spectroscopy, laser-tissue interactions, and retinal plasticity. Top 3 Takeaways "The [size] limitation for a retinal prosthesis is not in a fabrication side. The limitation is an interface with neurons" Allergan acquired Oculeve but then didn't do much with it seemingly because they already had a more profitable drug on the market "Stanford is industry-friendly, encouraging commercialization, basically making things...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is a corporate executive with thirty years of corporate, governance and strategy consulting experience. She oversees ’s global programs, including its centers and their services. These include: board evaluations, professional certification and training, its global registry of qualified directors, Board Bona Fide®, its strategic partnership programs and its Boardwise center.  Top 3 Takeaways  "It's really important to know that if we want to be good at our work, then we've got to explore things outside of our normal swim lanes. And when we do that, it gives us a different view or...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is the program officer at the in the National Institutes of Health (NIH). They are launching the NIH Blueprint Medtech (links below) which aims to help incubate growing neurotech companies go from Bench to Bedside.    Top 3 Takeaways  "We're funding individual projects and trying to help groups in the past have struggled... to get funding and to get all the way to in human trials. The Blueprint Medtech resource is meant to derisk later investment and grants for companies "We saw some great programs... having difficulty when they come in - Can we decrease the activation...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Jon is the founder of (quality management software exclusively for medical device companies) & a medical device guru with nearly 20 years industry experience. Jon knows the best medical device companies in the world use quality as an accelerator. That's why he created Greenlight Guru to help companies move beyond compliance to True Quality.   Top 3 Takeaways If it isn't documented, it didn't happen. One particular audit didn't take four days. It took two days because the Greenlight system made it so much simpler. Greenlight Guru also has an academy to teach people about the...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Professor is the Professor of AI & Neuroscience at the Dept. of Computing and the Dept. of Bioengineering at Imperial College London. His work is in Machine Learning and eye tracking to improve neurotechnologies. Top 3 Takeaways "What we do is we get people to move into our living lab/studio flat and they live their daily lives, and we record everything that they do, how they do, where they look, we record the eye movements, the body movements, and everything." "The more subjects you add to your dataset from different datasets, the worse the performance of the system becomes." A...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is the Co-Founder and Chairman of which has the Utah Electrode Array, the only FDA-approved neural implantable device. Blackrock Neurotech recently closed a $10 million financing round, led by Christian Angermayer's re.Mind Capital with participation from Peter Thiel, German entrepreneur Tim Sievers, and Sorenson Impact's University Venture Fund II.   Top 3 Takeaways "In the end, you have to have the drive. It has to be a passion. And then you will find a way because very often in life, you will find that, just when you need it, all that you really need is one door opening at the right...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is a neurosurgeon who is also the founder of Synchron which makes the . Instead of requiring invasive brain surgery for implantable neural devices, they are able to use stents such as those used in cardiology to collect neural signals   Top 3 Takeaways: Stentrode implantation it's one of the simplest stent procedures. Got a $40 million Series B funding round from Khosla Ventures thanks to the success of in-human studies as well as the potential to piggyback off of existing hospital technologies "We see an avenue for a range of products that do not require open brain surgery that reaches...

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Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Giovanni Lauricella is a Vice President of the Mullings Group which is a Medical Device Technology recruitment firm. He helps startups in the neurotech space find talented people from the most experienced down to the entry-level positions.   Top 3 Takeaways: "Always pull on your network, always pull on that trust factor because people go to work for people. That's what they do, especially in startups and especially really early-stage startups" "If you want to be headhunted, make yourself available to be found, build your LinkedIn profile. Let us find you, there's tools and platforms...

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Kunal Ghosh on the advantages of imaging tools for neuronal recordings & pattern recognition with Inscopix show art Kunal Ghosh on the advantages of imaging tools for neuronal recordings & pattern recognition with Inscopix

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is the founder and CEO of which uses imaging tools to understand the brain in both health and disease.    Top Three Takeaways: Miniscopes were invented out of a need for tools that have the ability to monitor and record large-scale neural circuit activity Imaging tools have the advantage of scale, single-cell resolution, longitudinal recording capabilities, and labelling for specific cell types Inscopix technology has enabled over 150 scientific papers   0:45 "Do you wanna introduce yourself a little bit?"  5:00 "Why you did choose an imaging technique instead of,...

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Kunal Ghosh is the founder and CEO of Inscopix which uses imaging tools to understand the brain in both health and disease. 

 

Top Three Takeaways:

  • Miniscopes were invented out of a need for tools that have the ability to monitor and record large-scale neural circuit activity
  • Imaging tools have the advantage of scale, single-cell resolution, longitudinal recording capabilities, and labelling for specific cell types
  • Inscopix technology has enabled over 150 scientific papers

 

0:45 "Do you wanna introduce yourself a little bit?" 

5:00 "Why you did choose an imaging technique instead of, something else?"

12:00 "How did you since you started with the research and then leave academia, go into industry, and create this company. How did you do that?"

17:15 "Are you guys partnering with these big pharmaceutical companies or more on the FDA side?"

22:30 "What is the role of this circuit dysregulation almost like fingerprints of the, of these deviations from the norm. Is this something that you can visualize even predict before it happens?"

27:15 "How does it work with sifting through enormous amounts of data?"

32:45 "What are you excited about now?"

Head-mounted Calcium Imaging on a Rhesus Macaque paper link