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Podcast 713: Oral Ketamine

Emergency Medical Minute

Release Date: 09/20/2021

Podcast 1019: Trauma Blunt Cardiovascular Injuries (BCVI) show art Podcast 1019: Trauma Blunt Cardiovascular Injuries (BCVI)

Emergency Medical Minute

Contributor: Aaron Lessen, MD Educational Pearls:  Blunt cerebrovascular injury (BCVI) BCVI is a traumatic injury to the carotid or vertebral arteries Patients may initially have no neurologic symptoms In some cases, a thrombus can form at the site of the injury and later cause ischemic stroke, sometimes hours after the original trauma CT angiography (CTA) of the neck is a useful screening tool for BCVI HIstorically, CTA was reserved for patients with high-risk mechanisms or neurologic symptoms CTA screening has expanded as understanding of BCVIs and their prevention...

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Podcast 1018: Occult Ventricular Fibrillation on Echocardiography show art Podcast 1018: Occult Ventricular Fibrillation on Echocardiography

Emergency Medical Minute

Contributor: Aaron Lessen, MD Educational Pearls: Big question in cardiac arrest: is the rhythm shockable? Shockable: ventricular fibrillation (VF) and pulseless ventricular tachycardia Non-shockable: asystole and pulseless electrical activity (PEA) Rhythm classification is typically based on ECG, but echocardiography can directly visualize myocardial fibrillation Occult VF: a rhythm that appears non-shockable on ECG but demonstrates VF on echocardiography A 2025 multicenter prospective study looked at 811 patients with out-of-hospital cardiac arrest 5.3% had occult VF...

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Podcast 1017: CPR Hand Placement show art Podcast 1017: CPR Hand Placement

Emergency Medical Minute

Contributor: Taylor Lynch, MD Educational Pearls:  CPR is an important life-saving measure designed for anyone to perform. Chest compressions works by two mechanisms:  Cardiac pump: Direct squeezing of the heart Thoracic pump: Increasing intrathoracic pressure, causing increased blood flow Proper hand placement per current AHA guidelines:  Hands are placed in the center of the chest, on the lower half of the sternum A recent study challenged this approach, using TEE during chest compressions to visualize the cardiac structures being compressed. They found...

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Podcast 1016: Hypokalemia show art Podcast 1016: Hypokalemia

Emergency Medical Minute

Contributor: Meghan Hurley, MD Educational Pearls: What is hypokalemia? Hypokalemia is when the measured blood level of potassium falls below 3.5 mEq/L (normal 3.5 - 5.2 mEq/L).  Can generally be considered in mild (3.0 - 3.5 mEq/L); moderate (2.5 - 2.9 mEq/L); and severe (<2.5 mEq/L) categories with differing treatment goals based on levels.  Should be noted that blood levels of potassium can be low while total body potassium is normal due to intracellular shift by certain agents like β-2 agonists (e.g. Albuterol) or insulin. There is no appreciable loss of insulin despite...

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Podcast 1015: Calcium in Hyperkalemia show art Podcast 1015: Calcium in Hyperkalemia

Emergency Medical Minute

Contributor: Meghan Hurley, MD Educational Pearls: What is hyperkalemia? Hyperkalemia is when the measured blood level of potassium reaches above 5.2 - 5.5 mEq/L (normal 3.5 - 5.2 mEq/L).  What are common causes of hyperkalemia?  Chronic or acute kidney disease. Medications that impact the Renin-Angiotensin-Aldosterone-System (RAAS).  Hypoaldosteronism and primary adrenal insufficiency (Addison’s Disease). What are concerns of hyperkalemia? The biggest concern with hyperkalemia is the impact on the cardiac conduction system. At differing levels of...

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Podcast 1014: Eating and Drinking on Shift show art Podcast 1014: Eating and Drinking on Shift

Emergency Medical Minute

Contributor; Aaron Lessen, MD Educational Pearls: A 2026 survey asked Canadian emergency medicine (EM) physicians about their eating and drinking habits while on shift. Among 527 respondents, 35% reported that they never or hardly ever ate during shifts, and 37% said the same about drinking water. Lack of time was the most commonly cited barrier, reported by 91% of respondents. Lack of available food, personal health goals, perceived mental clarity, and emergency department culture were also commonly identified factors. Physicians who did not eat or drink on shift often reported...

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Podcast 1013: Thoracotomy Indications show art Podcast 1013: Thoracotomy Indications

Emergency Medical Minute

Contributor; Taylor Lynch, MD Educational Pearls: Thoracotomy  Thoracotomy is used in traumatic cardiac arrest to replace conventional CPR with direct access to the chest. Goals include identifying and controlling reversible causes of bleeding, prioritizing blood flow to the heart and brain, and performing open cardiac massage. Trauma categories Penetrating trauma: Gunshot wounds and stab wounds. Has a higher chance of survival because the injury may be localized and directly repairable. Cardiac stab wounds may have the highest survivability because the defect can be...

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Podcast 1012: Meth Sedation show art Podcast 1012: Meth Sedation

Emergency Medical Minute

Contributor: Aaron Lessen, MD Educational Pearls:    Agitated patients who are intoxicated with methamphetamine pose a unique challenge when selecting a sedative to counter their symptoms. Is there a superior medication? A recent study compared the efficacy of commonly used medications for methamphetamine-induced agitation in the emergency department. The study compared IM Droperidol 5mg, IM Olanzapine 10mg, IM Midazolam 5mg, and IM Lorazepam 2mg. The study concluded that Droperidol, Olanzapine, and Midazolam performed similarly, with a median time to adequate sedation of...

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Podcast 1011: Creepy Crawlies show art Podcast 1011: Creepy Crawlies

Emergency Medical Minute

Contributor: Meghan Hurley, MD Educational Pearls: What animal is the most lethal to humans?  Depending on how we define lethal, and animal, this answer is actually not straight forward.  Globally and in the U.S. the most lethal animal is humans, accounting for ~436,000 to ~20,000 deaths (homicides) per year on average respectively.  In the United States the most lethal animal is of the Hymenoptera order (bees, wasps, and hornets). It accounts for approximately ~60 deaths per year from anaphylaxis. Globally the number is harder to track, but is estimated between...

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Podcast 1010: First Pass Intubation Success show art Podcast 1010: First Pass Intubation Success

Emergency Medical Minute

Contributor: Travis Barlock, MD Educational Pearls:   First-pass success is critical to limit complications from apnea, hypoxia, and airway trauma.  Complication rate for patients intubated on the first pass is 14% Complication rates increase to 47% after two attempts, 64% after three, and 71% after the fourth attempt   How to improve likelihood of first-pass success: Use Video laryngoscopy (VL). VL increases chance of first-pass success to 85% from 71% Use a bougie, especially in patients with anatomically difficult or otherwise obstructed airways. The BEAM study...

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More Episodes

Contributor: Don Stader, MD

Educational Pearls:

  • Those on chronic opioid therapy may have high tolerance to opioids and/or opioid hyperalgesia
  • Ketamine is a good adjunct for pain control in patients on chronic opioid therapy
  • To avoid the time constraints often required to push ketamine intravenously, it can be given orally:
    • Ketamine IV 25-50 mg (~0.01-0.03 mg/kg) as a single dose by mouth

References

Blonk M, Koder B, et al. Use of oral ketamine in chronic pain management: A review. European Journal of Pain. 2009.

Schwenk ES, et al. Consensus guidelines on the use of intravenous ketamine infusions for acute pain management from the America Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine and the American Society of Anesthesiologists. Reg Anesth Pain Med. 2018.

Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD

 

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