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49 - The Ether Dome

Bedside Rounds

Release Date: 09/30/2019

74 - R2D2 show art 74 - R2D2

Bedside Rounds

What does it mean when a computer can make better medical decisions than a human? The progress in large language models, and in particular the popularity of ChatGPT, has brought these questions to the forefront in 2023, but we’ve been discussing this for over 50 years. In this episode, Dr. Shani Herzig and I are going all the way back to the early 1970s with the invention of AAPHELP, the first real clinical decision support system, and the first time doctors had to contemplate working with – or competing against – computer systems.

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Bedside Rounds

What happens when a patient far from surgical care – say, at the bottom of the Pacific ocean on a submarine, or at a research base in Antarctica in the middle of the winter – develops a surgical abdomen? This dilemma was the impetus to build the first truly effective clinical decision support system – and to grapple with what it means when a computer can make better medical decisions than a doctor. In this episode, part one of three, we discuss the dramatic stories of appendectomies at Novolazarevskaya and aboard the submarine Seadragon. Also, there’s a brand new #AdamAnswers about the...

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Bedside Rounds

American doctors spend the majority of their time during the day on the computer, either writing or reading notes about their patients; only a small fraction is spent with the human beings in their care. Technology itself – especially the electronic medical record – has often been blamed for this. But in this episode – a recorded grand rounds that I gave at the San Francisco VA in 2022 – I argue that this alienation has its roots in the way we’ve decided to organize clinical data, and the assumptions that we’ve made about the nature of medical care. In particular, I’m going to...

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Bedside Rounds

In the past episode, cultural and medical historians Lakshmi Krishnan and Mike Neuss discussed the history of the actual work of the doctor – Holmesian detective, data entry clerk, or something else altogether. In this episode, we conclude our discussion by talking about what type of metaphors are best suited for clinical work. Plus a brand new #AdamAnswers about the reason that American doctors are so obsessed with using, well, the # symbol in our notes.

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Bedside Rounds

What do doctors actually do? Are they Sherlockian detectives, hunting down obscure clues to solve intractable cases? Are they virtuosic experts, training for half a lifetime to bring the latest science to bear to cure disease? Or are they clerks, whose main job is to collect and enter data into the electronic health record? In this episode, Adam is joined by medical and cultural historians Lakshmi Krishnan and Mike Neuss to discuss the stories we tell about our own work – and how this often conflicts with the realities of clinical practice.

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Bedside Rounds

How do doctors actually think? And if we can answer that, can we train a computer to do a better job? In the post-WW2 period, a group of iconoclastic physicians set about to redefine the nature and structure of clinical reasoning and tried to build a diagnostic machine. Though they would ultimately fail, their failure set the stage for the birth of the electronic health records, formalized the review of systems, and set up a metacognitive conflict that remains unresolved to this day. This episode, entitled “The Database,” is the second part of this on the history of diagnosis with Gurpreet...

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Bedside Rounds

Internal medicine physicians like to pride ourselves on our clinical reasoning – the ability to talk to any patient, pluck out seemingly random bits of information, and make a mystery diagnosis. But how does this actually work? In this episode, called The History, I’ll be joined by Gurpreet Dhaliwal as we explore the beginnings of our understanding on how clinical reasoning works – starting in the middle of the 19th century with polar tensions between two ways of approaching our patients that are still felt today. Along the way, we’ll talk about the American Civil War, Car Talk,...

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The Facemaker with Dr. Lindsey Fitzharris (#histmedconsultservice) show art The Facemaker with Dr. Lindsey Fitzharris (#histmedconsultservice)

Bedside Rounds

Modern plastic surgery was born out of the horrors of trench warfare in World War I. In this episode, Adam interviews historian Lindsey Fitzharris about her new book The Facemaker, about the life of surgeon Harold Gillies and his quest to rebuild his patients' faces. 

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Bedside Rounds

In the early 19th century, a strange new illness, seemingly unknown to medicine, ravaged settler communities in the American Middle West. As fierce debates about this new disease, now called milk sickness, raged – was it from toxic swamp gasses? arsenic in the soil? infectious microorganisms? from the poor constitutions of the settlers – an irregular medicine woman named Dr. Anna and an indigenous Shawnee healer discovered the cause of the disease and successfully prevented it in their community. But their discovery went unheeded for over a half century. This is a live podcast that I gave...

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Bedside Rounds

Burnout seems to stalk healthcare workers; between a third and a half of doctors and nurses had symptoms of burnout BEFORE the COVID-19 pandemic. Major medical associations have recognized burnout as a serious problem and the condition is being added to ICD-11 as an “occupational phenomenon.” How has burnout gotten so bad? In this episode, the first #HistMedConsultService, I’m joined by historians of healthcare and emotions Agnes Arnold-Forster and Sam Schotland to historicize burnout.

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More Episodes

The world before anesthesia was brutal -- surgeons inflicted torture on largely conscious patients, hoping to finish an operation as quickly as possible. But all of that changed with the introduction of inhaled ether. This episode covers the context behind the discovery of etherization, with myths about screaming medicinal plants, a “missing recipe” of medieval general anesthesia, 19th century recreational drug use, and a controversy carved in granite.

 

Sources:

  1. Brown, M. The Palgrave Handbook of the History of Surgery. 327–348 (2017). doi:10.1057/978-1-349-95260-1_16 
  2. Dorrington, K. & Poole, W. The first intravenous anaesthetic: how well was it managed and its potential realized? Bja Br J Anaesth 110, 7–12 (2013). 
  3. Robinson, D. H. & Toledo, A. H. Historical Development of Modern Anesthesia. J Invest Surg 25, 141–149 (2012). 
  4. Chidiac, E. J., Kaddoum, R. N. & Fuleihan, S. F. Mandragora. Anesthesia Analgesia 115, 1437–1441 (2012). 
  5. Vargas, I. Ether Frolic: The Day Pain Stopped. Bulletin Anesthesia Hist 28, 53–56 (2010). 
  6. Whalen, F. X., Bacon, D. R. & Smith, H. M. Inhaled anesthetics: an historical overview. Best Pract Res Clin Anaesthesiol 19, 323–330 (2005). 
  7. Prioreschi, P. Medieval anesthesia – the spongia somnifera. Med Hypotheses 61, 213–219 (2003). 
  8. Stallings, S. & Montagne, M. A chronicle of anesthesia discovery in New England. Pharm Hist 35, 77–80 (1993). 
  9. Litoff, J. & Pernick, M. S. A Calculus of Suffering: Pain, Professionalism, and Anesthesia in Nineteenth-Century America. Am Hist Rev 91, 176 (1986). 
  10. Leake, C. D. Letheon: The Cadenced Story of Anesthesia. Science 199, 857–860 (1978). 
  11. CRAWFORD W. LONG (1815-1878) DISCOVERER OF ETHER FOR ANESTHESIA. Jama 194, 1008–1009 (1965). 
  12. Riches, E. Samuel Pepys and His Stones. J Urology 118, 148–151 (1977). 
  13. CWRIGHT, F. The early history of ether. Anaesthesia 15, 67–69 (1960). 
  14. Insensibility during Surgical Operations Produced by Inhalation. New Engl J Medicine 35, 379–382 (1846). 
  15. SURGICAL HUMBUG. Lancet 5, 646–647 (1826). 

Locations in Boston:

Ether Monument (https://www.atlasobscura.com/places/ether-monument)

Ether Dome (https://www.atlasobscura.com/places/ether-dome?utm_source=atlas-forum&utm_medium=referral)

Warren Anatomic Museum (https://www.atlasobscura.com/places/warren-anatomical-museum)