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In the News.. Islet cell implant update, BG check with radio waves, preschool T1D detection & more!

Diabetes Connections with Stacey Simms Type 1 Diabetes

Release Date: 09/09/2022

When your sibling has T1D: Stacey's daughter Lea shares her story show art When your sibling has T1D: Stacey's daughter Lea shares her story

Diabetes Connections with Stacey Simms Type 1 Diabetes

Stacey talks a lot about her son with type 1 but, as many of you know, she also has a daughter who doesn’t have diabetes. What’s it like to grow up with a sibling who gets more attention for something you can’t do anything about? Lea was five when her little brother was diagnosed – she’s now 21 and she has a lot to say. This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider. Episode Transcription Below (or coming soon!) Please visit our Sponsors & Partners - they help make the show possible!

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In the News... Teplizumab approved, Twitter mess for Lilly, Medtronic 7-day infusion set launches, and more! show art In the News... Teplizumab approved, Twitter mess for Lilly, Medtronic 7-day infusion set launches, and more!

Diabetes Connections with Stacey Simms Type 1 Diabetes

It’s in the News.. the top diabetes stories of the past seven days. This week, the first drug to prevent T1D for any length of time is approved, Eli Lilly takes a financial hit from a Twitter impersonation stunt, Medtronic's 7-day pump infusion set is ready for consumers, Dexcom's G7 gets great reviews from older folks and educators for ease of use, a new study about light at night and diabetes and more! Learn more about the T1D Exchange: Episode Transcription Below (or coming soon!) Please visit our Sponsors & Partners - they help make the show possible!   Hello and welcome...

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The Future of Long-Term CGM Systems with Senseonics CMO Dr. Fran Kaufman show art The Future of Long-Term CGM Systems with Senseonics CMO Dr. Fran Kaufman

Diabetes Connections with Stacey Simms Type 1 Diabetes

Eversense is a CGM that goes under the skin and stays there for up to six months. The company that makes it has big plans to make that time period longer and to make the sensor even more accurate. Stacey talks to Senseonics Chief Medical Officer Dr. Francine Kaufman. They had a wide ranging conversation about everything from sensor length to interoperability and working with different pump systems as well as access and so much more. This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider. Episode Transcription Below (or...

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In the News.. Diabetes supply prices capped, New integrated insulin pen system, T1D diagnosis study and more! show art In the News.. Diabetes supply prices capped, New integrated insulin pen system, T1D diagnosis study and more!

Diabetes Connections with Stacey Simms Type 1 Diabetes

It's in the News.. the top diabetes stories of the past seven days. This week, one state caps not just insulin prices, but diabetes supplies for some, Lilly is out with a new integrated pen system, new study look at DKA at diagnosis of type 1 and what that means for health issues later on, and more! Learn more about the T1D Exchange: Episode Transcription Below (or coming soon!) Please visit our Sponsors & Partners - they help make the show possible!   Hello and welcome to Diabetes Connections In the News! I’m Stacey Simms and these are the top diabetes stories and headlines...

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Tips, Tricks and Building a Community: Meet Tom From Type One Talks show art Tips, Tricks and Building a Community: Meet Tom From Type One Talks

Diabetes Connections with Stacey Simms Type 1 Diabetes

Type One Talks is a popular YouTube channel with videos that help manage all sort of technology and situations around diabetes. But its host and founder says he wasn’t always that interested a diabetes deep dive. It all changed with his first CGM. Tom was an accountant in his former life so he really does love numbers. We’ll talk about his diagnosis as a child in the former Czechoslovakia, how much everything has changed and why he started making videos about diabetes technology, basically experimenting on himself. This podcast is not intended as medical advice. If you have those kinds of...

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In the News... Researching T2D drugs for T1D, Medtronic 780G moves ahead, Diabetes Awareness Month stuff and more! show art In the News... Researching T2D drugs for T1D, Medtronic 780G moves ahead, Diabetes Awareness Month stuff and more!

Diabetes Connections with Stacey Simms Type 1 Diabetes

It's in the News.. the top diabetes stories of the past seven days. This week: new research looks at off-label use of GLP and SGLT drugs for people with type 1, Medtronic gets 780G approval in Canada, finger prick early detection of type 1, and lots going on for Diabetes Awareness Month. Episode Transcription Below (or coming soon!) Please visit our Sponsors & Partners - they help make the show possible! Hello and welcome to Diabetes Connections In the News! I’m Stacey Simms and these are the top diabetes stories and headlines of the past seven days. XX In the news is brought to...

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What are your What are your "Rules of Engagement?"- Conversations around CGM

Diabetes Connections with Stacey Simms Type 1 Diabetes

When it comes to using a CGM, the first question you may ask is, "How quickly can I get one?!" But this week, you'll hear there are a few other questions you may want to ask in order to get the most out of continuous glucose monitoring. In this excerpt from "Still the World's Worst Diabetes Mom: More Real Life Stories of Parenting a Child With Type 1 Diabetes," Stacey lays out conversations to have BEFORE you decide whether and how to use a CGM. Thinking this out can make your child’s use of a CGM more effective and with less stress for you. It may even be helpful for adults considering...

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Building Community Through Storytelling: SixUntilMe's Kerri Sparling show art Building Community Through Storytelling: SixUntilMe's Kerri Sparling

Diabetes Connections with Stacey Simms Type 1 Diabetes

The author of Kerri Sparling, isn’t blogging any more, but she’s still looking for stories of connection and community built around conversation For 14 years Kerri wrote a daily blog about her experience with type 1. She put aside SixUntilMe in 2019. We’re going to talk about what she thinks about the online community these days and what’s next. This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider. Episode Transcription Below (or coming soon!) Please visit our Sponsors & Partners - they help make the...

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In the News... insulin rationing, DIY tech studies, iLet pump research and more! show art In the News... insulin rationing, DIY tech studies, iLet pump research and more!

Diabetes Connections with Stacey Simms Type 1 Diabetes

It’s It’s “In the News…” a look at the top diabetes stories and headlines of the past seven days. This week: a troubling new study about how many people with diabetes ration insulin, a new study looks at OpenAPS compared to traditional pumps, more research on Beta Bionics' iLet pump, an old diabetes drug might help in the fight against dementia, and more! Learn more about the T1D Exchange: https://t1dexchange.org/stacey/ Episode Transcription Below (or coming soon!) Please visit our Sponsors & Partners - they help make the show possible! Hello and welcome to Diabetes...

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What happens at T1D teen retreats (and what adults can learn from them) show art What happens at T1D teen retreats (and what adults can learn from them)

Diabetes Connections with Stacey Simms Type 1 Diabetes

Who would volunteer to spend a weekend with a bunch of teens with type 1? A bunch of people who’ve been there! We’re talking about teen retreats – and what even adults can learn – about the power of connection. Patrick Mertes has lived with type 1 since he was a child. If that name sounds remember, he’s one of the climbers from the 50-in-50 project where he and a friend climbed the highest peak in all 50 states in 50 days a couple of years back. He also runs a fantastic family and teen retreat in North Carolina. This podcast is not intended as medical advice. If you have those kinds...

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More Episodes

It’s in the news! The top stories and headlines around the diabetes community this week include: A new way to sneak islet cells into the body without needing immunosuppressive drugs, routinely checking young children for T1D markets before symptoms show up, a non invasive way to measure blood glucose uses Radio Frequency, a DIY movement publishes in the New England Journal of Medicine and more!

Check out Stacey's book: The World's Worst Diabetes Mom!

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Episode Transcription Below (or coming soon!)

Please visit our Sponsors & Partners - they help make the show possible!

*Click here to learn more about OMNIPOD*

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*Click here to learn more about DEXCOM*

Hello and welcome to Diabetes Connections In the News! I’m Stacey Simms and these are the top diabetes stories and headlines of the past seven days.
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In the news is brought to you by T1D Exchange! T1D Exchange is a nonprofit organization dedicated to improving outcomes for the entire T1D population.
https://t1dexchange.org/stacey/
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French biopharma company Adocia has established a first proof of concept for its AdoShell Islets implant. This was in rats.. but they achieved glycemic control without insulin injections and without immunosuppressive drugs for four months.
AdoShell Islets is an immuno-protective synthetic biomaterial that secrets insulin in response to blood glucose levels. The physical barrier formed by the AdoShell biomaterial allows the implanted cells to be invisible to the host’s immune system while allowing the necessary physiological exchanges to occur for the survival and function of the islets.
These researchers are optimistic that their unique approach can be translated from one species to another.
https://www.labiotech.eu/trends-news/adocia-implants-diabetes/
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Can starting a closed loop system right away help keep kids with type 1 in the honeymoon stage longer? New study says.. probably not.
The latest findings are from the Closed Loop From Onset in Type 1 Diabetes (CLOuD) trial, a multicenter, open-label, parallel-group, randomized study, published online September 7 in the New England Journal of Medicine by Charlotte K. Boughton, PhD, and colleagues.
In CLOuD, 97 youths aged 10-17 years were randomized to hybrid closed-loop therapy or standard insulin therapy (control) within 21 days of type 1 diabetes diagnosis. I found this a bit confusing, in the standard insulin therapy groups, participants could switch to insulin pump therapy or use flash or continuous glucose monitoring (CGM) or approved closed-loop systems if clinically indicated. So this isn’t comparing an AID system to MDI.
At 12 months, there were no differences after a mixed-meal tolerance test, with levels declining in both groups and dropping further by 24 months. Interestingly, they said glycemic control didn’t differ significantly between the two groups.

https://www.medscape.com/viewarticle/980356
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Moving closer to a non-invasive way to measure blood glucose. The GlucoRx BioXensor uses radio frequency technology alongside a multiple sensor approach to measure blood glucose levels every minute. This looks to be about the size of a Libre 3 or Dexcom G7..
It’s said to have smart alarms and remote monitoring capability and just sticks on the skin. The MARD is 10 point 4, which is less accurate than CGMs on the market now, but much better than any other noninvasive device to make it this far. In addition to measuring blood glucose the makers say it can measure oxygen levels, ECG, respiration rate, heart rate, temperature, activity, sleep, and early fall detection.
Pivotal clinical study later this year and then the say they’ll submit for European approval.
https://www.med-technews.com/news/latest-medtech-news/glucorx-and-cardiff-university-to-bring-out-non-invasive-con/
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RESEARCHERS in Oxford have launched the first UK study in the general population to test for early markers of type 1 diabetes, before children develop symptoms or need insulin. They’re offering a finger stick test when children have their pre-school vaccination. Very small start, only 60 kids, but these researchers say with a recent, more accurate test to check for markers early on, they hope to find more children before DKA sets in.
https://www.oxfordmail.co.uk/news/20977659.oxford-scientists-launch-study-early-markers-type-1-diabetes-children/
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The first Randomized Controlled Trial on open source automated insulin delivery (AID) is now published in a peer-reviewed medical journal. Big news for and from the we are not waiting crowd.
The CREATE Trial evaluated the efficacy and safety of an open-source system using the OpenAPS algorithm in a modified version of AndroidAPS. This study included children and adults and found that across all ages, time in range was 14 percent higher than those who used commercial hybrid closed loop systems. There’s more to it, and I”ll link it up, but this study concluded that a widely used open-source AID solution, works and is safe. Congrats to Dana Lewis and all the researchers involved.
https://diyps.org/2022/09/07/nejm-publishes-rct-on-open-source-automated-insulin-delivery-openaps-algorithm-in-androidaps-in-the-create-trial/
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Back to the news in a moment but first..
The T1D Exchange Registry is a research study conducted online over time, designed to foster innovation and improve the lives of people with T1D. The platform is open to both adults and children with T1D living in the U.S. Personal information remains confidential and participation is fully voluntary. Once enrolled, participants will complete annual surveys and have the opportunity to sign up for other studies on specific topics related to T1D. The registry aims to improve knowledge of T1D, accelerate the discovery and development of new treatments and technologies, and generate evidence to support policy or insurance changes that help the T1D community. By sharing opinions, experiences and data, patients can help advance meaningful T1D treatment, care and policy.
The registry is now available on the T1D Exchange website and is simple to navigate, mobile and user-friendly. For more information or to register, go to www.t1dregistry.org/stacey
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Medtronic is waiting for FDA clearing of the new 780G.. already approved in Europe. New study results published in The Lancet Diabetes & Endocrinology, Medtronic announced Thursday put the AID pump up against multiple daily injections plus CGM. Small study, 82 people, all with an A1C over 8. After using the 780G for six months, the group saw a reduction of 1.4 percent in their levels with a quarter of that group dropping their A1C below 7. None of the MDI group dropped to that level. Time in range saw most improvement overnight.
The MiniMed 780G system has been cleared in Europe since 2020. Medtronic submitted it to the FDA for U.S. approval in the spring of 2021 but is still awaiting a decision, slowed down by the roadblocks caused by a late 2021 warning letter from the agency that called out quality control issues at the California headquarters of its diabetes business.
https://www.fiercebiotech.com/medtech/medtronics-new-minimed-insulin-pump-adds-27-boost-time-range-study-finds
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Change at one of the top posts at Dexcom. Jake Leach moves from Chief Technology Officer to Chief operating officer. He’s been at the company since 2004 to work on the first commercial Dexcom CGM system. He’s been a frequent guest of the show and we hope that continues.
https://www.businesswire.com/news/home/20220831005236/en/DexCom-Promotes-Jake-Leach-to-Chief-Operating-Officer
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Next week we’re looking ahead to the New York City Marthong. Beyond Type 1 puts together a gret team each year and I’m taking to one of the runners. He’s also nabbed a spot in the world series of poker – which do you think is tougher on his type 1 diabetes? This past episode is all about Omnipod 5 – a panel of people who’ve sued it for a few weeks now.. and the director of medical affairs to answer your questions.
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That’s In the News for this week.. if you like it, please share it! Thanks for joining me! See you back here soon.