loader from loading.io

10 trillion cells and 10 billion miles of DNA

Innovation Unleashed Podcast

Release Date: 03/13/2018

Using DNA to Treat Genetic Diseases show art Using DNA to Treat Genetic Diseases

Innovation Unleashed Podcast

Working to treat genetic diseases is complicated, demanding work and requires the commitment and intellectual power of people who are dedicated to finding answers. Today’s guest Scott Sneddon is one of those people. Scott is the President & CEO of Sharp Edge Labs. He is an entrepreneur and scientist trained in chemistry and biology with an emphasis on computational methods.

info_outline
Tummlers Help Create Successful Innovation Communities show art Tummlers Help Create Successful Innovation Communities

Innovation Unleashed Podcast

Our guest on this episode knows all about entrepreneurs helping entrepreneurs. Kit Mueller is known as a Serial Tummler or a person who connects people and makes things happen. And that’s what Kit has been doing in Pittsburgh’s tech sector for years. Kit describes himself as an “Entrepreneurial Community Builder with a proven history of entrepreneurial success in the software and creative industries.

info_outline
Patients First show art Patients First

Innovation Unleashed Podcast

On this episode, we are going to talk with Patrick Colletti the COO and newly named Chief Innovation Officer of Net Health, a company that creates software solutions for specialized outpatient care. Net Health serves healthcare professionals essentially all of the largest hospital chains in the US as well as private practices around the country.

info_outline
Survey Says show art Survey Says

Innovation Unleashed Podcast

Are opinion polls important? What is the science behind them? Are they sophisticated analyses or back of the envelope calculations? Should we trust what they say? Can they be manipulated and misused? John Dick is the CEO of CivicScience. CivicScience provides strategic insight services to decision-makers at the largest brands, media companies, and investment firms in the world.

info_outline
More People. More Big Ideas. show art More People. More Big Ideas.

Innovation Unleashed Podcast

Our guest, Audrey Russo, is an impassioned thought leader about technology and demographics being codependent drivers of the Pittsburgh economy and the success of the technologies that are developed here.

info_outline
The Science of Working in Teams  show art The Science of Working in Teams

Innovation Unleashed Podcast

We are fortunate to be joined on this episode by a renowned expert in the study of teams and collective intelligence. Anita Woolley, is an Associate Professor of Organizational Behavior and Theory at the Tepper School of Business, Carnegie Mellon University. She has a PhD in Organizational Behavior from Harvard University, where she also earned Bachelor’s and Master’s degrees.

info_outline
Reshaping the World with Machine Learning show art Reshaping the World with Machine Learning

Innovation Unleashed Podcast

It is interesting that on this episode, we are joined by John Kitchin, a chemical engineering expert who is using machine learning to develop new tools to change the way that research is being conducted.

info_outline
Saving the World’s Water from Our Own Destruction  show art Saving the World’s Water from Our Own Destruction

Innovation Unleashed Podcast

On this episode, we are joined by two pioneers who are working to use chemistry and technology to safely reduce/eliminate hazardous chemical contaminants and pathogens from water. Dr. Terry Collins is the Teresa Heinz Professor in Green Chemistry, Chemistry and Director, Institute for Green Science at Carnegie Mellon University and Professor Ryan Sullivan, working in both Chemistry and Mechanical Engineering at Carnegie Mellon University.

info_outline
The Making of Schmoopie, Uncle Sam, Betsy Ross, Pepperoni, and Monster Max  show art The Making of Schmoopie, Uncle Sam, Betsy Ross, Pepperoni, and Monster Max

Innovation Unleashed Podcast

On this episode, our guest is a serial entrepreneur and a world-renowned inventor. He has been called a snake charmer……and has famously charmed snakes by the name of schmoopie, Uncle Sam, Betsy Ross, Pepperoni, and Monster Max - - - Mechanical robotic snakes that can explore tight spaces, swim, climb poles…. and solve big problems.

info_outline
Mission Critical Platform show art Mission Critical Platform

Innovation Unleashed Podcast

On this episode, we are joined in the studio by two big-thinking entrepreneurs who are proving that that they can provide the right ecosystem to manage this colossal global data. Particularly in healthcare. Joshua “Dax” Cabrera and Patrick Mulcahy formed their company MEDSiS in 2014.

info_outline
 
More Episodes

According to the National Institutes of Health, a genome is an organism’s complete set of DNA, including all of its genes. Each genome contains all of the information needed to build and maintain that organism. In us, a copy of the entire genome—more than 3 billion DNA base pairs—is contained in all cells that have a nucleus. Each human cell has around 6 feet of DNA. Let's say each human has around 10 trillion cells (this is actually a low ball estimate). This would mean that each person has around 60 trillion feet or around 10 billion miles of DNA inside of them. The Earth is about 93 million miles away from the sun.

And as we head toward 10 billion people on the planet, that is a lot of DNA.

According to the National Human Genome Research Institute, the genomes of any two people are more than 99% the same. That tiny fraction of the genome that varies from person to person is very important. The variations of our DNA are part of what makes each of us distinctive and unique. These variations affect the color of a person’s eyes, hair and skin. Importantly, they also influence a person’s risk of disease and response to medicine. Visionary scientists are unravelling our genetic information so that they can personalize how we are treated. Dr. Dietrich Stephan, our guest on this episode, has been at the forefront of personalized medicine through genetic laser guidance, for decades. He is a human geneticist and entrepreneur. In December 2017, the University of Pittsburgh announced the launch of LifeX™, an initiative that will provide expertise, capital and working space to new companies addressing the most complex challenges facing modern medicine. The organization will be headed by Dietrich Stephan, PhD, Professor and chairman of the Department of Human Genetics. Let’s listen as he shares his views on personalizing medicine to cure disease and keep people well.