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Is Our Age-Related Loss Of The Brain's Hypothalamic Stem Cells The Primary Driver Of Aging?- Episode 127

Gladden Longevity Podcast -- formerly Living Beyond 120

Release Date: 04/21/2022

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Dr. Gladden sits with Dr. Sheldon Jordan, an artist innovator, interventional neurologist, and neurological expert. Dr. Sheldon takes a well-rounded research-based approach, which has enabled him to develop some of the most innovative neurological treatments in the world. Dr. Sheldon believes he has come across the key drivers of the aging process by analyzing the brain.

Dr. Gladden introduces Dr. Sheldon and speaks about his experience and profile (1:00)

Dr. Sheldon defines aging as the interaction between re-genesis, growth, and the opposite, which is destruction (3:21)

Dr. Sheldon talks about how kids with autism always have a large head and a large brain as they have too much growth without pruning (6:05)

Dr. Gladden mentions how again is not a linear process but an exponential process(8:35)

Dr. Sheldon says that it is possible to get early markers for Alzheimer's and Parkinson's disease by using magnetic resonance imaging (11:35)

Dr. Sheldon goes on to mention how comparison of a healthy individual with others with diagnostics label help catch the disease early (13:33)

Dr. Sheldon talks about how segmenting the population by decades could help comparison among people of different ages (14:59)

Dr. Sheldon describes how an MRI scanner is used to get the kind of data needed to help patients and how it’s done (18:00)

Dr. Sheldon mentions how different tests are carried out to help people preempt any issue or disease that is not yet visible (21:05)

Dr. Sheldon talks about working with the FDA and various companies to develop regenerative products that can be delivered to the brain using targeted energy sources (23:00)

Dr. Sheldon talks about how you can make a certain mouse old by destroying cells in the hypothalamus and make it young again by replacing it with certain regenerative elements (25:40)

Dr. Gladden questions Dr. Sheldon about the techniques he uses to characterize the status of hypothalamic stem cells (29:10)

Dr. Sheldon talks about how the exosomes from a blood sample or spinal fluid sample can be collected and analyzed (33:16)

Dr. Sheldon mentions how it is essential to take action before ailments and other diseases progress and become irreversible (38:00)

Dr. Sheldon talks about the importance of the what you breathe and what you put inside your body (41:00)

Dr. Sheldon makes us understand that how we eat, sleep, and exercise matter (44:00)

Dr. Sheldon ends by mentioning that diet, exercise, and sleep are important to anyone who wants to make 100 the new 30 and also the importance of spiritual health (46:10)

Dr. Gladden also mentions that when people dam the flow of love, they pay a physiological price (48:40)

Dr. Sheldon ends with the advice that it is essential to have someone to love, someone who loves you, and something to look forward to (49:50)