MCAT Basics (from MedSchoolCoach)
In this episode, we explore enzyme kinetics and inhibition, key concepts for the MCAT Bio/Biochem section. We’ll cover how enzymes accelerate biological reactions by lowering activation energy and introduce two models for enzyme-substrate interaction: the lock-and-key model and the induced fit model. You'll learn how to apply the Michaelis-Menten equation, focusing on factors like Km and Vmax to understand enzyme efficiency and substrate binding. We’ll also break down the different types of enzyme inhibition—competitive, non-competitive, and uncompetitive—and their effects on enzyme...
info_outline Biomolecule Structure, Naming, And FunctionMCAT Basics (from MedSchoolCoach)
In this episode, we’ll learn the intricate world of biomolecule structure, naming, and function. We'll explore the structural nuances between glucose and fructose and unravel the complexities of glycosidic linkages in sucrose. We'll also examine the vital roles of fatty acids, the composition of triglycerides and phospholipids, and their impact on cell membrane architecture and fluidity. Plus, we discuss cholesterol's bidirectional regulation of membrane stability and the contrasting roles of LDL and HDL in cardiovascular health. We’ll dive into the essential structures and functions of...
info_outline Metabolism: Gluconeogenesis, Pentose Phosphate Pathway, and MoreMCAT Basics (from MedSchoolCoach)
In this episode, we're diving deep into the nuanced aspects of metabolism that are essential yet less prominently featured on the MCAT. We'll cover gluconeogenesis, the pentose phosphate pathway, and ketone body generation—topics that, while subtle, play a crucial role in your comprehensive understanding of biochemistry. We'll explore how your body manages glucose levels, the functions of NADPH, how glycogen is synthesized and broken down, and the metabolic adaptations during periods of low glucose. Visit for more help with the MCAT. Jump into the conversation: (00:00) Intro...
info_outline Metabolism: Glycolysis, Krebs Cycle, Electron Transport ChainMCAT Basics (from MedSchoolCoach)
In this episode, Sam Smith covers the intricacies of metabolism, focusing on glycolysis, the Krebs cycle, and the electron transport chain. First, the podcast explores the process of glycolysis, breaking down the key enzymes, intermediates, and regulation points. Next is the citric acid cycle, examining its regulation, energy production, and the roles of specific enzymes and intermediates. Lastly, we look at the electron transport chain and discuss how electrons are transferred through the five complexes, creating a proton gradient that drives ATP synthase to produce ATP. Visit ...
info_outline Acids and BasesMCAT Basics (from MedSchoolCoach)
Acids and bases are foundational topics in chemistry, crucial for understanding various biological and chemical systems you'll encounter in the MCAT. In this episode, host Sam Smith discusses the selection and use of indicators in titrations to the pH at the equivalence point and the importance of buffers in maintaining physiological pH levels. You'll learn about the Henderson-Hasselbalch equation, the blood buffer system, and how to tackle common problems involving acids and bases. Plus, we'll break down strong and weak acids and the significance of their dissociation constants. This episode...
info_outline The Nervous SystemMCAT Basics (from MedSchoolCoach)
A foundational topic for the MCAT is the nervous system, appearing in several exam sections and impacting everything from neurotransmission to brain structure. In this episode, Sam Smith walks us through the nervous system, covering its major components and functions. From the organization of the central and peripheral nervous systems to neurotransmitters and brain structures, Sam provides clear explanations to help you understand key topics like the autonomic nervous system's fight-or-flight response, brain imaging techniques, and more. Visit for more help with the MCAT. Jump into the...
info_outline Amino AcidsMCAT Basics (from MedSchoolCoach)
Amino acids are the building blocks of life and an essential topic for the MCAT. In this episode, host Sam Smith takes us through the key concepts of amino acids, including their structures, naming conventions, and roles in protein formation. We’ll cover the differences between hydrophobic and hydrophilic amino acids, how to memorize single-letter abbreviations, and the importance of charged amino acids in physiological conditions. Additionally, Sam touches on mutations and how they can affect protein folding and enzyme function. Visit for more help with the MCAT. Jump into the...
info_outline GluconeogenesisMCAT Basics (from MedSchoolCoach)
One of the body's key survival mechanisms is gluconeogenesis, a vital metabolic process, and the body's clever way of making glucose when supplies are low. On this episode of the MCAT Basics podcast, guest host Alex Starks walks through the process of gluconeogenesis. He explains how the body generates glucose when levels drop. Highlighting the liver's role, Alex explains how amino acids, lactate, and glycerol are converted into glucose. The episode also touches on the energy demands of the process and why muscle cells aren't involved in gluconeogenesis. Visit for more help with the...
info_outline Electron Transport ChainMCAT Basics (from MedSchoolCoach)
The electron transport chain is a fundamental pathway in biochemistry, critical for understanding the energy production that powers cellular function. In this episode, guest host Alex Starks breaks down the intricate process of the electron transport chain (ETC). Building on previous discussions of glucose metabolism, Alex walks through the components that play key roles in the movement of electrons through complexes within the inner mitochondrial membrane. We also cover the functions of coenzyme Q and cytochrome c, as well as oxygen’s critical role in completing the process. Visit ...
info_outline The Krebs CycleMCAT Basics (from MedSchoolCoach)
One of the most fundamental biochemical processes is the Krebs cycle. This metabolic pathway plays a critical role in both the Chem Phys and Bio/Biochem sections of the MCAT, so understanding it is key. In this episode, our guest host, Alex Starks, walks us through the transformation of pyruvate into acetyl CoA via the Pyruvate Dehydrogenase Complex (PDC). We’ll explore how thioester bonds help transfer energy within the cycle, how acetyl CoA combines with oxaloacetate to form citrate, the difference between enzymes like synthetases and synthases, and how GTP is produced. We’ll also make...
info_outlineIn this episode, we dive into psychological disorders, a crucial topic for the Psych/Soc section of the MCAT. We’ll start by defining what a psychological disorder is, highlighting key concepts like significant stress and deviant behavior, and discussing how they’re classified using the DSM-5.
You'll learn about various categories of disorders, including anxiety disorders, obsessive-compulsive disorders, trauma and stressor-related disorders, and more. We’ll explore the biopsychosocial and biomedical approaches to understanding these conditions, providing insight into the biological, psychological, and social factors that contribute to mental health issues.
By the end of this episode, you'll have a comprehensive understanding of the different types of psychological disorders and how they are categorized and treated, helping you tackle related questions on the MCAT.
Visit MedSchoolCoach.com for more help with the MCAT.
Jump into the conversation:
(00:00) Intro: Med School Coach promotion and podcast introduction
(01:03) Overview of Psychological Disorders: Episode topics and structure
(02:13) Defining Psychological Disorders: Significant stress and deviant behavior
(05:29) Biopsychosocial vs. Biomedical Approaches: Holistic vs. traditional perspectives
(09:18) DSM-5 Classification of Psychological Disorders: Overview of main categories
(10:37) Anxiety Disorders: Fear and anxiety beyond normal levels
(16:43) Obsessive-Compulsive Disorder: Obsessions and compulsions explained
(18:20) Trauma and Stressor-Related Disorders: PTSD and related disorders
(19:19) Somatic Symptom Disorders: Physical symptoms causing mental distress
(22:01) Bipolar and Related Disorders: Mood swings and differentiating Bipolar I and II