How To Combat Diseases of Aging Caused By Oxidative Stress With Dr. Mark Gordon
Release Date: 04/06/2016
Getting Back on Track: Why Medications May No Bet a Good Idea
The Ironman Executive
Our guest for the week is Hyla Cass, an integrative psychiatrist practiced in the field even before the term was coined. Her 25-year long practice is marked by the non-drug, natural system boosting approach, which landed her the nation-wide acclaim along with numerous awards. She is here to talk to us about the subversive effects of medications, the systems approach to medicine, as well as about enhancing our cognitive performance. Side-effect Are Still Effects Stuffing oneself with medication rarely comes without the so-called side-effects. What is important to realize, however, is that the...
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Epigenetics – the Meeting Point between Genetics and Nutrition
The Ironman Executive
Our guest for the week is Dr. Lucia Aronica, a postdoctoral fellow at Stanford Cancer Center and an expert on epigenetic medicine. Her main focus revolves around genomics of nutrition, that is, the correlation between diet and the changes in epigenetic landscape. Holding a Ph.D. in Molecular Biology, Dr. Aronica has spent the last decade researching the influence lifestyle has on our genomes. Her endeavors landed her not just a few recognitions, Marie Curie Global Fellowship Award being one of them. In this interview, she shares her thoughts on food, diet, as well as sheds some light on the...
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New Studies in Longevity and Age Extension
The Ironman Executive
Aaron Traywick is the founder at Ascendance Biomedical where they focus on helping people get the treatments and care they need to save their lives. They also specialize in helping fund and facilitate research by taking initial studies off shore before bringing the data back to the FDA. Learn more about this process as well as two studies they're currently working on. He shares some of the results they're seeing and potential for the industry with this particular treatment for longevity and life extension overall. Enrollment is currently open for trials to test “Bucky-balls” (also known as...
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Daniel Schmachtenberger - Systems Approach to Your Health, Wellness and Business
The Ironman Executive
Daniel Schmachtenberger enlightens us on how to use a science systems approach to our health, wellness and business. Listen in on how human behavior affects the systems we function in every day - economic, social, political and how we can make these systems stronger and more resilient by changing the human body's systems.
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The Epigenetics of Well-Being With Dr. Steven Cole
The Ironman Executive
Dr. Steven Cole is the Director the UCLA Social Genomics Laboratory. He has been pioneering human social genomics as a Professor of Medicine and Psychiatry and Behavioral Science at the UCLA School of Medicine. Dr. Cole’s studies have concentrated on Genomics and computational bioinformatics to map the biological pathways by which social environments affect gene expression by viral cancer and immune cell genomes. Epigenetics of Wellbeing Biological effects of stress Our bodies are not built to be stressed out and miserable all of the time. We are only capable of handling stress in...
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Genetics and Genomics - How They Relate to Dietary Patterns
The Ironman Executive
With today's guest Nicola Pirastu we learn the difference between several common genetic terms, how your diet choices may or may not be good for your personal health and how your diet can impact your genes and their expressions. Genetics Vs Genomics The terms genetics and genomics sound alike, and they are often used interchangeably. But there are some important distinctions and similarities between genetics and genomics and how they affect our dietary patterns. But firstly, what do they mean? Genetics is the study of heredity, or how the characteristics of living organisms are transmitted...
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The Father of Gene Therapy Shares What the Future Holds With Genomics
The Ironman Executive
Pioneer in the world of Gene therapy, Dr. Theodore Friedman shares with us today the exciting future of what gene therapy holds. Listen in as we hear how manipulating certain lacking or misbehaving genes from causing disease has been proven in several types of diseases through clinical experimentation and how it will benefit future generations. We discuss whether or not it will be a solution to all disease. What the census is on how fast it will take or the prediction of genomic therapy within the scientific world. Gain greater awareness of gene modification within the world sport arena...
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Cracking the Aging Code with Josh Mitteldorf
The Ironman Executive
Welcome back to the Ironman Executive Podcast where today we talk with Josh Mitteldorf, he is both a researcher and science writer. He recently released a book called Cracking the Aging Code which not only transformed my perspectives on aging but will bring awareness and knowledge into your own understanding of aging. Learn the importance of epigenetics in aging as we discuss current research, research that may happen over the short term and long term in the science world in regards to how reversing aging may be possible. Caloric Restriction There is good evidence that suggests caloric...
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The Link Between Stress & Sleep With Dr. Kelly Olson
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Today we’re talking to Dr. Kelly Olson, an expert in the area of neuroscience, stress and sleep. We discuss chronic stress and adrenal fatigue, as well as some promising supplements and treatments to support healthy stress response and better sleep habits. Chronic Stress and Adrenal Fatigue We’re all aware of the negative impacts of stress, how it has a huge impact on aging and can create a low-grade inflammatory response that contributes to a high percentage of illnesses. Of course, there are also positive aspects to some types of stress. Acute stress can provide a benefit, but you need...
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How to Boost Performance, Attention and Cognition with Audio - Visual Entrainment with Dave Siever
The Ironman Executive
Today we’re talking to Dave Siever, an expert on the topics of neuro feedback and biofeedback. Dave discusses the audio visual entrainment (AVE) device – called the DAVID -- offered through his company Mind Alive, and how it can be used to optimize the brain in many different ways. Audio-Visual Entrainment vs. Audio-Visual Stimulation Dave explains how audio-visual entrainment is different from the audio-visual stimulation you’d get from, for example, watching TV, which doesn’t do much to benefit the brain. AVE, in contrast, provides a continuous stream of stimuli at a fairly steady...
info_outlineHow To Combat Diseases of Aging Caused By Oxidative Stress With Dr. Mark Gordon
Today we’re talking to Dr. Mark Gordon, a physician with over 20 years of experience in clinical cardiology. Dr. Gordon has participated in numerous pharmaceutical and medical device trials, and his passion for prevention has led him to focus his practice on preventative and integrative cardiology.
Dr. Gordon is currently focused on the hot topic of NRF2 and how it helps the body deal with oxidative stress, which is the root cause of hundreds of diseases. He explains that oxidative stress is like a rusting of the body from the inside out. It is created from free radicals, which are the highly unstable and destructive byproducts of metabolism created by our bodies every day.
The Relationship Between Oxidative Stress and Free Radicals
Dr. Gordon explains that oxidative stress and free radicals go hand in hand. And while some free radicals are actually beneficial – they can help heal infections by targeting bad bacteria — those produced above and beyond what’s necessary are responsible for diseases of aging like cancer and cardiovascular diseases, among countless others. Oxidative stress is essentially the free radical process run wild, which in turn causes damage to the cells.
For many years, the popular wisdom was that people could simply take loads of antioxidants to combat this process. But over the last 10 to 15 years, studies have shown detrimental effects of taking too many direct antioxidants.
Not only is it an ineffective way of dealing with oxidative stress that doesn’t reduce the risk of cardiovascular disease and cancer, it can also actually increase the risk in some individuals in whom the antioxidant is converted to a pro-oxidant.
Researchers are still learning more about this process, but the answer in the meantime is to boost the body’s built-in antioxidant defense system to buffer these effects, as opposed to relying on external sources.
Our body produces its own enzymes to combat the adverse effects of oxidative stress. But as we age, we produce fewer of this enzymes, giving free radicals more free reign to do damage.
How To Boost the Body’s Own Defense System
Around 2002, scientists dived into a hot new area of research revolving around NRF2. NRF2 is a messenger protein in all of the cells in the body that goes into a cell’s nucleus and turns on genes that code antioxidant proteins to fight off free radicals, thereby reducing oxidative stress.
We are born with the ability to make NRF2, and this system is critical for healthy aging.
As we age, there are several things that we can do to boost the body’s innate NRF2 system.
- Appropriate exercise: Daily moderate exercise (not too much and not too little) is essential.
- Cleaner Diet: Key ingredients in certain foods activate NRF2. These include foods featured in the Mediterranean and Okinawa diets. The standard American diet doesn’t contain most of these necessary components.
- Meditation: The cells in the brain don’t know don’t know whether stress is psychological or physical, so the response is the same — inflammation and oxidative stress. This is why meditation, prayer and other calming practices are effective.
- Protandim by LifeVantage: This supplement is derived from five plant-based ingredients based on traditional Chinese medicine and boosts NRF2 production in the body. Studies have shown it to be the most potent biochemical pathway to combat oxidative stress, and it is considered in the medical community to be an extraordinary therapeutic and preventative breakthrough.