891 - The (Misleading) Truth About Akkermansia
Dr. Ruscio Radio, DC: Health, Nutrition and Functional Healthcare
Release Date: 03/14/2024
Dr. Ruscio Radio, DC: Health, Nutrition and Functional Healthcare
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info_outlineHave you recently heard about Akkermansia and wondered what it's all about?
We know it’s a commensal bacteria that resides in the human gut, thriving in the mucus layer, but its popularity in the wellness world has many asking: Are the benefits truly substantial?
To answer this question let’s go over some common claims and what the research actually tells us.
Watch Next…
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These Probiotics Improve Leaky Gut by 82%: https://www.youtube.com/watch?v=CEt0kdT5AOU&t=239s
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NEW Science-Backed Ways to Improve Fatigue, Insomnia, Stress: https://www.youtube.com/watch?v=kEmj83EIfyU&t=8s
Read Next:
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Why Probiotic Biodiversity is More Important than Strain: https://drruscio.com/what-is-the-best-probiotic-strain/
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The Best Probiotic Protocol? The Triple Therapy Approach: https://drruscio.com/triple-therapy-probiotic-protocol/
Timestamps
00:00 Intro
02:06 What is Akkermansia?
04:29 “Only strain that lives and regulates the gut lining”
05:10 “Major part of the microbiome”
06:49 “Low levels are associated with poor gut health”
07:56 “Good for metabolism & gut health”
10:30 Beware of “Positive Publication Bias”
12:14 Other probiotics that improve gut health
12:54 Increasing Akkermansia naturally
17:49 Key takeaways
18:54 Recommended protocol
Featured Studies
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Akkermansia muciniphila: 18 years after its first discovery https://www.frontiersin.org/articles/10.3389/fgstr.2022.1024393/full
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Akkermansia muciniphila, a human intestinal mucin-degrading bacterium https://pubmed.ncbi.nlm.nih.gov/15388697/
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Role of Akkermansia in Human Diseases: https://pubmed.ncbi.nlm.nih.gov/37111034/
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Akkermansia muciniphila improves glucose homeostasis https://pubmed.ncbi.nlm.nih.gov/33820962/
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Spatial Characteristics of Colonic Mucosa-Associated Gut Microbiota in Humans https://pubmed.ncbi.nlm.nih.gov/34223947/
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Next-Generation Probiotic in Modulating Human Metabolic Homeostasis and Disease Progression https://pubmed.ncbi.nlm.nih.gov/36835309/
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Gut Bifidobacteria Populations in Human Health and Aging https://pubmed.ncbi.nlm.nih.gov/27594848/
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Akkermansia muciniphila in the Human GI Tract https://pubmed.ncbi.nlm.nih.gov/30041463/
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Intestinal Lactobacillus in health and disease, a driver or just along for the ride? https://pubmed.ncbi.nlm.nih.gov/28866243/
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Akkermansia lower in severe obesity https://pubmed.ncbi.nlm.nih.gov/31265324/
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Impairment of Insulin Secretion and Glucose Homeostasis in Lean Type 2 Diabetes https://pubmed.ncbi.nlm.nih.gov/34085773/
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Akkermansia muciniphila in IBD: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9853388/
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Mucosa-Associated Microbiota in Patients with IBS https://pubmed.ncbi.nlm.nih.gov/33271532/
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Differences in the Composition of Gut Microbiota between Patients with Parkinson's Disease https://pubmed.ncbi.nlm.nih.gov/34884399/
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Gut microbiome of MS patients https://pubmed.ncbi.nlm.nih.gov/36113426/
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Probiotics fortify intestinal barrier function https://pubmed.ncbi.nlm.nih.gov/37168869/
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Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in IBS https://pubmed.ncbi.nlm.nih.gov/37686889/
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Clinical effects and gut microbiota changes of using probiotics, prebiotics or synbiotics in IBD https://pubmed.ncbi.nlm.nih.gov/33555375/
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Effects of probiotics on functional constipation https://pubmed.ncbi.nlm.nih.gov/32005532/
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Probiotics for Preventing and Treating SIBO https://pubmed.ncbi.nlm.nih.gov/28267052/
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Probiotics as an effective therapeutic approach in alleviating depression symptoms https://pubmed.ncbi.nlm.nih.gov/35348020/
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Diets that differ in their FODMAP content alter the colonic luminal microenvironment https://pubmed.ncbi.nlm.nih.gov/25016597/
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Prebiotic Effect on Gut With Altered FODMAP Intake in Patients with Crohn's Disease https://pubmed.ncbi.nlm.nih.gov/27077959/
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Efficacy of a low FODMAP diet in IBS https://pubmed.ncbi.nlm.nih.gov/34376515/
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Lipoprotein and Endotoxemia Improvement in Metabolic Syndrome with Gut Microbiota Modification https://pubmed.ncbi.nlm.nih.gov/31451009/
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Regulation of gut microbiome by keto diet https://pubmed.ncbi.nlm.nih.gov/36313018/
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Islamic fasting leads to an increased Akkermansia https://pubmed.ncbi.nlm.nih.gov/31854308/
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Strategies to promote Akkermansia https://pubmed.ncbi.nlm.nih.gov/30416539/
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Adjuvant Probiotics Attenuate Glycemic Levels and Inflammatory Cytokines in Type 1 Diabetes Mellitus https://pubmed.ncbi.nlm.nih.gov/35299968/
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*Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.