Ep. 47- Genetic Big data for Personalized Medicine with Sean Jackewicz
The Straight from a Scientist Podcast
Release Date: 06/15/2019
The Straight from a Scientist Podcast
This weeks episode combines several topics you may have heard of, but never thought about in the same context! Diabetes and epigenetics are two well-researched topics, but not in the context of fetal development. During pregnancy, the placenta is the highway that connects a mother and fetus, so when epigenetics act on the placenta, they could have huge effects on development of the fetus and/or the mother. We break it down straight from a scientist in this episode with Laetitia Myeyruix from UNC's School of Global Public Health, in the Department of...
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Join Lebaron (Lee) Agostini and Connor Wander in our FIRST VIDEO episode! This episode is all about Cancer Biology. Lee studies experimental cancer therapies for pancreatic cancer. New cancer therapies called combination or synergystic cancer therapies use multiple drug types to shut down, corner, and eliminate cancer cells in the body. The full video version of this episode is available on Nov 5th at 7PM EST ! Head on over to our YouTube Channel and check it out there! Also streaming (audio only) on all the usual platforms. Further information Here's a recent paper from Lee and his...
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What is Alzheimer's disease? Who can get Alzheimer's, and how does the disease progress? Maya Gostyla and Connor Wander break down the state of Alzheimer's disease treatments, risk factors, and potential breakthroughs in the field. Related Episodes If you like this episode, we have tons of podcasts on Alzheimer's disease! You can hear more about Maya and her research story in this episode. Further Reading about Alzheimer's disease Here's a great review from the experts on where Alzheimer's research and therapies are today. For more in-depth analysis of developments in...
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This week's episode is with the host of The Blunt Report podcast: Konner Blunt. Connor and Konner talked about ALzheimer's disease, the experience of podcasting, science communication, and Jiu Jitsu among other things. Check out The Blunt Report here: http://www.thebluntreport.com/ More about Alzheimer's disease: https://www.straightfromascientist.com/alzheimers-disease/
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Tayler is a PhD candidate in the College of Veterinary Medicine at Murdoch University in Perth, Western Australia. Her research focuses on the pharmacology and toxicology of supposed ‘fertility-boosting’ herbal supplements on sperm cells, using flow cytometry to elucidate their effects at a cellular level. She is also a science communicator in her spare time, and posts regular pharmacology-based series online. You can find her on Instagram at @taylercatherine Link to a good general review on oxidative stress: https://www.nature.com/articles/35041687 Link to a review of herbal medicine...
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In this episode, we chat with Sean Jackewicz. Sean's research in the lab has focused on cancer development and cancer therapies, while his work outside of the lab focuses on the role of genomics in people's lives. Sean is currently leading the development of a clinical genotyping tool that he hopes will give health practitioners the ability to personalize treatment plans for patients like never before. Sean is also passionate about communicating the upcoming changes in genetic technology.
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Alzheimer's disease is a terrifying neurodegenerative disorder characterized by impaired memory, cognitive deficits, and neuronal loss. With few treatments and no cure after decades of research, scientists are starting to think outside the box for better ways to ward off Alzheimer's disease. In this episode, we discuss the links between mental health and neurodegenerative disorders like Alzheimer's, and how common strategies for better mental health have great promise for Alzheimer's disease treatment. In general, the best protective strategies for Alzheimer's disease are things that improve...
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Genome-wide association studies, or GWAS, are very helpful in telling researchers where to focus their attention. GWAS identify genes or clusters of genes associated with greater risk for diseases and disorders. But GWAS aren't a silver bullet...
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Women are almost twice as likely to develop Alzheimer's disease as men. However, this is NOT because they live longer. When we look into the aging brain, males and females experience different timelines. The molecular underpinnings of these sex differences could make a huge impact on our understanding of Alzheimer's disease. Dr. Roberta Diaz Brinton is spearheading research into sex differences in Alzheimer's disease.
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This week's episode features another throwback recorded in San Diego, CA, where Connor Wander attended the BrightFocus Alzheimer's Disease Fast Track conference, followed by the Society for Neuroscience annual meeting. We talked with Dr. Elizabeth Head, who studies the link between Down Syndrome and Alzheimer's disease with the hopes of improving lives for both patient classes. Listen to hear about this super interesting and very promising work!
info_outlineSean Jackewicz is a research student at the University of Georgia who is studying for his degree in Genetics, with the goal of being a medical doctor. Sean's research in the lab has focused on cancer development and cancer therapies, while his work outside of the lab focuses on the role of genomics in people's lives. Sean is currently leading the development of a clinical genotyping tool that he hopes will give health practitioners the ability to personalize treatment plans for patients like never before. Sean is also passionate about communicating the upcoming change genetic technology will cause throughout all areas of life. The best way to talk with Sean and follow his journey through healthcare is through his Instagram: @chemical_reacsean