Live at SSO 2025: GNAS Inhibitor Novel Therapy for Appendiceal Mucinous Peritoneal Carcinomatosis
Release Date: 04/01/2025
ASO Article Series: Assessing the Evidence for and Utility of Gene Expression Profiling of Primary Cutaneous Melanoma
SurgOnc Today®
In this new episode of Speaking of SurgOnc, Dr. Rick Greene & Dr. Giorgos Karakousis discuss the article: "Assessing the Evidence for and Utility of Gene Expression Profiling of Primary Cutaneous Melanoma" from the March 2025 issue of the Annals of Surgical Oncology.
info_outline
SSO Education Series: Stressors in Your First Attending Job
SurgOnc Today®
After years of training and countless hours in the OR, the transition from fellowship to independent practice is one of the most challenging times in a surgeon’s career. In this podcast episode produced by the Fellows and Young Attendings Committee, Dr. Kathrine Kelly is joined by Dr. Mura Assifi and Dr. Michael Wach to discuss the stressors of starting out as a surgical oncologist. This is an honest conversation about building a surgical practice, managing complications, and the unique challenges we all face in the care of the complex cancer patient.
info_outline
Lessons Learned Series: Enhancing Enrollment in Clinical Trials - Perspective from Surgical Oncology Leaders
SurgOnc Today®
On this episode of SurgOnc Today, Dr. Mihir M. Shah speaks with Drs. Shailesh Shrikhande and Syed Ahmad about strategies to improve clinical trial enrollment, expand access, and strengthen participation in surgical oncology research.
info_outline
SSO Education Series: SSO 2026 Recap
SurgOnc Today®
In this episode of SurgOnc Today, members of the Constitution and Bylaws Committee interviewed attendees and faculty at the Society of Surgical Oncology 2026 meeting. Here, we present some of the most fantastic moments and give initial impressions of up and coming changes in care for patients with cancer. Thanks for listening, and we look forward to seeing everyone in 2027. As always, the Society of Surgical Oncology seeks to improve multidisciplinary patient care by advancing the science, education, and practice of cancer surgery worldwide.
info_outline
Lessons Learned Series: Understanding Why Clinical Trials Fail
SurgOnc Today®
On this episode of SurgOnc Today, Dr. Mihir M. Shah interviews Drs. Shailesh Shrikhande and Syed Ahmad about why clinical trials fail, highlighting key challenges in trial design, patient accrual, execution, and adoption in surgical oncology.
info_outline
SSO Education Series: Highlights from Advanced Cancer Therapies Meeting 2026
SurgOnc Today®
In this episode of SurgOnc Today, Drs. Kostas Chouliaras and Laura Enomoto recap the highlights from the Advanced Cancer Therapies Meeting in Fort Lauderdale, Florida, with Drs. Michael Lidsky, Jason Foster, and Mecker Moller.
info_outline
SOI Article Series:" Trends in incidence of oral cavity squamous cell carcinoma in the United States 2001-2019"
SurgOnc Today®
In this episode of SurgOnc Today's Surgical Oncology Insight series, Dr. Brittany Barber discusses with Dr. Sid Puram his paper “Trends in incidence of oral cavity squamous cell carcinoma in the United States 2001-2019".
info_outline
SSO Education Series—SSO, ACPMP, and PMP Pals: Educating the Medical Community & Patients on the International Patient Manifesto for Peritoneal Malignancies
SurgOnc Today®
In this episode of SurgOnc Today, key components of the recently launched Patient Manifesto will be discussed by appendix cancer medical experts and advocacy organizations. The goal of the podcast is to educate the medical community and our patient community on this manifesto and how we can work together to advance these key initiatives.
info_outline
ASO Article Series—Recurrence Patterns and Survival Outcomes in Clinical Stage IIB/IIC Melanoma: Can We Stratify Patients for Consideration of Neoadjuvant Immunotherapy
SurgOnc Today®
In this new episode of Speaking of SurgOnc, Dr. Rick Greene & Dr. Mohammed Farooq discuss the article "Recurrence Patterns and Survival Outcomes in Clinical Stage IIB/IIC Melanoma: Can We Stratify Patients for Consideration of Neoadjuvant Immunotherapy", from the January 2026 issue of the Annals of Surgical Oncology.
info_outline
SSO Education Series—From Gaps to Gains: Building Clinical Trials to Advance Cancer Equity in Low-Resource Settings
SurgOnc Today®
In this episode of SurgOnc Today, Drs. Cherif Boutros, Juliet Lumati, Sergio Aguilar, and Olusegun Alatise discuss the unique opportunities and challenges involved in launching and sustaining clinical trials in low-resource settings, with a spotlight on cancer care in Nigeria. Through a conversational format, the speakers will share personal experiences and lessons learned from building trial infrastructure, navigating ethics and regulatory hurdles, and ensuring data quality and patient retention in fragmented health systems. The session will also highlight strategies for securing funding,...
info_outlineAppendiceal neoplasms present with peritoneal carcinomatosis and despite aggressive CRS/HIPEC, often recur and are chemotherapy resistant. In this Colorectal DSWG SSO sponsored podcast episode, we discuss an overview of the recent publication of "Cyclin-Dependent Kinase 4/6 Inhibition as a Novel Therapy for Peritoneal Mucinous Carcinomatosis with GNAS Mutations" by Dr. Lowy's research lab at UCSD. The authors treated 16 patients in this Phase 2 study of oral Palbociclib in recurrent appendiceal adenocarcinoma patients and identified excellent treatment and long-term response with 13/16 of patients treated having reduction in CEA and excellent survival (median FU of 17.6 months, OS not reached). Dr Lowy provides informative background, study details and discusses next steps for this novel treatment approach.
A link to the paper in question is https://pubmed.ncbi.nlm.nih.gov/39413348/