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IFM | Innovative Diagnostic Tools and Workflows for Suspected Alzheimer’s in Primary Care

Inside Family Medicine

Release Date: 05/12/2026

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More Episodes

In this special edition of Inside Family Medicinesponsored by Roche Diagnostics, host Darren Sextro talks with brain health experts Deanna Willis, MD, MBA, a board-certified family physician, and Jared Brosch, MD, board-certified neurologist, on the use of blood-based biomarkers (BBBMs) in primary care settings for Alzheimer’s disease and related dementias. Their discussion explores how BBBMs can make referrals more efficient and enhance the evaluation of patients with cognitive decline. The conversation highlights the value of early diagnosis and therapy referrals as well as outlines effective workflow strategies for primary care teams. 

 

This episode is brought to you by Roche Diagnostics. 

 

Topics by Timestamp 

00:00 Introduction 

01:03 Meet the experts 

02:22 Dr. Willis’ journey 

04:32 Dr. Brosch’s journey 

05:32 Connection between family medicine and neurology 

07:24 New tools for early detection 

11:19 Workflow models and biomarkers 

14:08 Best practices for referrals 

16:35 Biomarkers in practice 

19:47 Conclusion and additional resources 

 

Additional Resources: 

Roche Diagnostics Elecsys Phospho-Tau (181P) Plasma decision summary 

2024 CEOi recommendations for clinical implementation of blood-based biomarkers for Alzheimer's disease: https://doi.org/10.1002/alz.14184 

2025 Alzheimer’s Association clinical guidelines for primary carehttps://doi.org/10.1002/alz.14333 

Implementing early detection of cognitive impairment in primary care to improve care for older adults: https://doi.org/10.1111/joim.20098 

Brain health hub on AAFP.org including newest brain health resources 

Disclaimer: Copyright 2026. AAFP. The views presented in this broadcast are the speaker’s own and do not represent those of AAFP. The information presented is for general, educational, or entertainment purposes and should not be considered legal, health, financial, or other advice.  AAFP makes no representation as to the accuracy or completeness of the information and is not responsible for results that may arise from its use.  Consult an appropriate professional concerning your specific situation and respective governing bodies for applicable laws. Reference to any specific product or entity does not constitute an endorsement or recommendation by AAFP unless specifically stated otherwise.  AAFP and the AAFP logo are registered trademarks of American Academy of Family Physicians.