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Ep. 11: Alzheimers, Axons, and Fruit Flies with Maya Gosztyla

The Straight from a Scientist Podcast

Release Date: 02/11/2018

Ep56- Unlocking Genetic Regulation show art Ep56- Unlocking Genetic Regulation

The Straight from a Scientist Podcast

  How did you get so put together?  DNA is the blueprint, but it doesn't determine everything.  DNA gets turned into RNA, and then finally into proteins that help build your body and brain.  But there are SO many steps in that process that affect the final product- you.   The sum of these steps is a process called genetic regulation.  Genetic regulation makes sure that not all of our genes are expressed and turned into protein at the same time and same place- that would be a mess! This episode is all about genetic regulation by long, non-coding RNAs...

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Ep55- Fetal Vulnerability to Cannabis and Alcohol show art Ep55- Fetal Vulnerability to Cannabis and Alcohol

The Straight from a Scientist Podcast

Marijuana and other cannabis products are becoming increasingly available across the country, and while compounds like CBD have been shown to be safe and even helpful in adults, the side effects of cannabis products are relatively unknown when it comes to the developing fetus. We've known that alcohol causes birth defects for over 40 years, causing a condition called Fetal Alcohol Syndrome (FAS) and the greater spectrum of Fetal Alcohol Spectrum Disorders .   But alcohol isn't the only commonly used substance to cause birth defects.   Dr. Parnell's lab and others shows that...

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E54- Supermassive Black Holes in Dwarf Galaxies show art E54- Supermassive Black Holes in Dwarf Galaxies

The Straight from a Scientist Podcast

This week's episode is about the big things in life- specifically, supermassive black holes in dwarf galaxies!  Connor Wander sits down with Mugdha Polimera from UNC to talk about her work studying supermassive black holes and how their frequency in dwarf (smaller) galaxies can teach us about the formation of the universe.  She quite literally looks back in time! Mugdha explains how she studies such huge elements so far away, what her studies could mean for our understanding of the universe,  reviews her journey to be an astrophysicist, comments on some popular science myths,...

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Ep 53 - How Bacteria Survive the Immune System show art Ep 53 - How Bacteria Survive the Immune System

The Straight from a Scientist Podcast

This episode is all about bad bugs.  Specifically, a flesh-eating bacteria strain called Staphylococcus aureus (S.aureus).  S. aureus is a very common bacteria that's best known for becoming resistant to antibiotics, and becoming MRSA.  Bacteria and the immune system are always at war with each other.  Antibiotics can give the body the edge in this battle, but common resistance is making this much harder in hospitals and homes across the world.  Bacteria survive these antibiotics and the immune system is left to clean up the mess.  Currently, S. aureus is a major...

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Ep 52 - Diabetes and Placental Epigenetics show art Ep 52 - Diabetes and Placental Epigenetics

The Straight from a Scientist Podcast

  This weeks episode combines several topics you may have heard of, but never thought about in the same context!  Diabetes and epigenetics are two well-researched topics, but not in the context of fetal development.  During pregnancy, the placenta is the highway that connects a mother and fetus, so when epigenetics act on the placenta, they could have huge effects on development of the fetus and/or the mother.   We break it down straight from a scientist in this episode with Laetitia Myeyruix from in the .  I learned a LOT from this episode, and I'm sure you...

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Ep. 51 – New Cancer Therapies & Targeting Cancer Biology show art Ep. 51 – New Cancer Therapies & Targeting Cancer Biology

The Straight from a Scientist Podcast

Join Lebaron (Lee) Agostini and Connor Wander in our FIRST VIDEO episode! This episode is all about Cancer Biology. Lee studies experimental cancer therapies for pancreatic cancer. New cancer therapies called combination or synergystic cancer therapies use multiple drug types to shut down, corner, and eliminate cancer cells in the body. The of this episode is available on Nov 5th at 7PM EST ! Head on over to our check it out there! Also streaming (audio only) on all the usual platforms. Further information Here's a recent paper from Lee and his lab at Jefferson University: Any...

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Ep.50 - Alzheimer's disease FAQ show art Ep.50 - Alzheimer's disease FAQ

The Straight from a Scientist Podcast

What is Alzheimer's disease? Who can get Alzheimer's, and how does the disease progress?  Maya Gostyla and Connor Wander break down the state of Alzheimer's disease treatments, risk factors, and potential breakthroughs in the field.   Related Episodes If you like this episode, we have tons of You can hear more about   Further Reading about Alzheimer's disease from the experts on where Alzheimer's research and therapies are today. For more in-depth analysis of developments in AD and other neurodegenerative diseases, check out  for Alzheimer’s disease background reading....

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Ep. 49 - Alzheimer's disease overview with Konner Blunt show art Ep. 49 - Alzheimer's disease overview with Konner Blunt

The Straight from a Scientist Podcast

This week's episode is with the host of The Blunt Report podcast: Konner Blunt.  Connor and Konner talked about ALzheimer's disease, the experience of podcasting, science communication, and Jiu Jitsu among other things.    Check out The Blunt Report here:   More about Alzheimer's disease:     

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Ep. 48- Are Herbal Supplements Effective? Using Modern Science to Investigate Ancient Medicines with Tayler Catherine show art Ep. 48- Are Herbal Supplements Effective? Using Modern Science to Investigate Ancient Medicines with Tayler Catherine

The Straight from a Scientist Podcast

Tayler is a PhD candidate in the College of Veterinary Medicine at Murdoch University in Perth, Western Australia. Her research focuses on the pharmacology and toxicology of supposed ‘fertility-boosting’ herbal supplements on sperm cells, using flow cytometry to elucidate their effects at a cellular level. She is also a science communicator in her spare time, and posts regular pharmacology-based series online. You can find her on Instagram at Link to a good general review on oxidative stress: Link to a review of herbal medicine safety issues:

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Ep. 47- Genetic Big data for Personalized Medicine with Sean Jackewicz show art Ep. 47- Genetic Big data for Personalized Medicine with Sean Jackewicz

The Straight from a Scientist Podcast

In this episode, we chat with Sean Jackewicz. Sean's research in the lab has focused on cancer development and cancer therapies, while his work outside of the lab focuses on the role of genomics in people's lives. Sean is currently leading the development of a clinical genotyping tool that he hopes will give health practitioners the ability to personalize treatment plans for patients like never before. Sean is also passionate about communicating the upcoming changes in genetic technology.

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More Episodes

This interview podcast features Maya Gosztyla, an undergraduate researcher at THE Ohio State University. Maya researches the genetics of axon guidance, or brain wiring in fruit flies, and runs her own Alzheimer's Disease learning blog called AlzScience. We discuss her research, how she balances work with free time, and how she worked her way into her first research lab without hands-on experience.

 

Here's a great post by Maya on AlzScience describing Alzheimer's Disease 

Here are her latest posts.  Highly recommend for those looking to learn more about Alzheimer's Disease!

@AlzScience Facebook

@AlzScience Twitter

Stay tuned for a special Alzheimer's Disease roundtable podcast with Maya and Connor, releasing later this week!  We'll discuss the idea that Amyloid Beta may not be simply a villain...

 

Any other questions?  Let us know!  We appreciate your feedback.

You can now support the podcast at https://www.patreon.com/sfspodcast.  Many thanks to our past and present supporters! 

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