loader from loading.io

Ep. 32: Search and Destroy in HIV Therapy Part II - with Aaron Devanathan and Connor Wander

The Straight from a Scientist Podcast

Release Date: 08/20/2018

E54- Supermassive Black Holes in Dwarf Galaxies show art E54- Supermassive Black Holes in Dwarf Galaxies

The Straight from a Scientist Podcast

This week's episode is about the big things in life- specifically, supermassive black holes in dwarf galaxies!  Connor Wander sits down with Mugdha Polimera from UNC to talk about her work studying supermassive black holes and how their frequency in dwarf (smaller) galaxies can teach us about the formation of the universe.  She quite literally looks back in time! Mugdha explains how she studies such huge elements so far away, what her studies could mean for our understanding of the universe,  reviews her journey to be an astrophysicist, comments on some popular science myths,...

info_outline
Ep 53 - How Bacteria Survive the Immune System show art Ep 53 - How Bacteria Survive the Immune System

The Straight from a Scientist Podcast

This episode is all about bad bugs.  Specifically, a flesh-eating bacteria strain called Staphylococcus aureus (S.aureus).  S. aureus is a very common bacteria that's best known for becoming resistant to antibiotics, and becoming MRSA.  Bacteria and the immune system are always at war with each other.  Antibiotics can give the body the edge in this battle, but common resistance is making this much harder in hospitals and homes across the world.  Bacteria survive these antibiotics and the immune system is left to clean up the mess.  Currently, S. aureus is a major...

info_outline
Ep 52 - Diabetes and Placental Epigenetics show art Ep 52 - Diabetes and Placental Epigenetics

The Straight from a Scientist Podcast

  This weeks episode combines several topics you may have heard of, but never thought about in the same context!  Diabetes and epigenetics are two well-researched topics, but not in the context of fetal development.  During pregnancy, the placenta is the highway that connects a mother and fetus, so when epigenetics act on the placenta, they could have huge effects on development of the fetus and/or the mother.   We break it down straight from a scientist in this episode with Laetitia Myeyruix from in the .  I learned a LOT from this episode, and I'm sure you...

info_outline
Ep. 51 – New Cancer Therapies & Targeting Cancer Biology show art Ep. 51 – New Cancer Therapies & Targeting Cancer Biology

The Straight from a Scientist Podcast

Join Lebaron (Lee) Agostini and Connor Wander in our FIRST VIDEO episode! This episode is all about Cancer Biology. Lee studies experimental cancer therapies for pancreatic cancer. New cancer therapies called combination or synergystic cancer therapies use multiple drug types to shut down, corner, and eliminate cancer cells in the body. The of this episode is available on Nov 5th at 7PM EST ! Head on over to our check it out there! Also streaming (audio only) on all the usual platforms. Further information Here's a recent paper from Lee and his lab at Jefferson University: Any...

info_outline
Ep.50 - Alzheimer's disease FAQ show art Ep.50 - Alzheimer's disease FAQ

The Straight from a Scientist Podcast

What is Alzheimer's disease? Who can get Alzheimer's, and how does the disease progress?  Maya Gostyla and Connor Wander break down the state of Alzheimer's disease treatments, risk factors, and potential breakthroughs in the field.   Related Episodes If you like this episode, we have tons of You can hear more about   Further Reading about Alzheimer's disease from the experts on where Alzheimer's research and therapies are today. For more in-depth analysis of developments in AD and other neurodegenerative diseases, check out  for Alzheimer’s disease background reading....

info_outline
Ep. 49 - Alzheimer's disease overview with Konner Blunt show art Ep. 49 - Alzheimer's disease overview with Konner Blunt

The Straight from a Scientist Podcast

This week's episode is with the host of The Blunt Report podcast: Konner Blunt.  Connor and Konner talked about ALzheimer's disease, the experience of podcasting, science communication, and Jiu Jitsu among other things.    Check out The Blunt Report here:   More about Alzheimer's disease:     

info_outline
Ep. 48- Are Herbal Supplements Effective? Using Modern Science to Investigate Ancient Medicines with Tayler Catherine show art Ep. 48- Are Herbal Supplements Effective? Using Modern Science to Investigate Ancient Medicines with Tayler Catherine

The Straight from a Scientist Podcast

Tayler is a PhD candidate in the College of Veterinary Medicine at Murdoch University in Perth, Western Australia. Her research focuses on the pharmacology and toxicology of supposed ‘fertility-boosting’ herbal supplements on sperm cells, using flow cytometry to elucidate their effects at a cellular level. She is also a science communicator in her spare time, and posts regular pharmacology-based series online. You can find her on Instagram at Link to a good general review on oxidative stress: Link to a review of herbal medicine safety issues:

info_outline
Ep. 47- Genetic Big data for Personalized Medicine with Sean Jackewicz show art Ep. 47- Genetic Big data for Personalized Medicine with Sean Jackewicz

The Straight from a Scientist Podcast

In this episode, we chat with Sean Jackewicz. Sean's research in the lab has focused on cancer development and cancer therapies, while his work outside of the lab focuses on the role of genomics in people's lives. Sean is currently leading the development of a clinical genotyping tool that he hopes will give health practitioners the ability to personalize treatment plans for patients like never before. Sean is also passionate about communicating the upcoming changes in genetic technology.

info_outline
Ep. 46- Stimulate Your Brain for Better Mental Health show art Ep. 46- Stimulate Your Brain for Better Mental Health

The Straight from a Scientist Podcast

Alzheimer's disease is a terrifying neurodegenerative disorder characterized by impaired memory, cognitive deficits, and neuronal loss. With few treatments and no cure after decades of research, scientists are starting to think outside the box for better ways to ward off Alzheimer's disease. In this episode, we discuss the links between mental health and neurodegenerative disorders like Alzheimer's, and how common strategies for better mental health have great promise for Alzheimer's disease treatment. In general, the best protective strategies for Alzheimer's disease are things that improve...

info_outline
Ep. 45: Applications and Limitations of GWAS with Dr. Liz Tunbridge show art Ep. 45: Applications and Limitations of GWAS with Dr. Liz Tunbridge

The Straight from a Scientist Podcast

Genome-wide association studies, or GWAS, are very helpful in telling researchers where to focus their attention. GWAS identify genes or clusters of genes associated with greater risk for diseases and disorders. But GWAS aren't a silver bullet...

info_outline
 
More Episodes

In our second interview with Aaron Devanathan, a PhD student in the Kashuba Lab at UNC Pharmacy, we dive deeper into the strategies researchers use on the cutting edge of HIV research, including the technical challenges, tools, and model systems that make the science possible.  We cover past, present, and future HIV therapies and also explore the innate immune system in aging and within the context of AIDS.  Next, Aaron discusses his recent experience in his clinical rotation at UNC hospitals, and his thoughts on being both a PharmD vs a Pharmacy PhD student.

About Aaron

Aaron studies HIV infection and elimination in the Department of Pharmacy at UNC Chapel Hill in the Angela Kashuba Lab.  HIV, or Human Immuno-deficiency Virus, is the virus that causes AIDS, or Acquired Immune Deficiency Syndrome.  While modern medicine has done wonders in treating the symptoms of an HIV infection, current drugs fail to eliminate the virus entirely.  This is because HIV is dispersed widely throughout the body.  Aaron studies how to hunt down HIV and destroy it, ultimately working towards an HIV cure.

More information

Learn more on the Angela Kashuba lab’s website

Follow the Kashuba lab on Twitter

Read about Angela Kashuba and her research on her UNC profile

 

Any other questions?  Let us know!  We appreciate your feedback.

You can now support the podcast at https://www.patreon.com/sfspodcast.  Many thanks to our past and present supporters! 

Thanks to Plant Warrior for their support.  Use discount code SFS10 at checkout for 10% off your purchase of plant-based protein.