Dr. Samuel Yanuck: Functional Immunology; Inflammation as a Barrier to Cellular Cleanup and Health
Release Date: 06/13/2025
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info_outlineDr. Yanuck provides a deep but practical understanding of how to approach complex immunological problems from an evidence-informed, hypothesis generating perspective that can provide a foundation for personalised clinical interventions. He explores the theme of the NLRP3 inflammasome, its intersection with autophagy and why this is relevant to many common immunological challenges including autoimmunity, metabolism, thyroid function, inflammation, T cell polarization and the capacity to clean up cells.
Guest:
Dr. Samuel Yanuck
About our guest:
Dr. Samuel Yanuck, DC, FACFN, FIAMA is an adjunct assistant professor in the Program on Integrative Medicine, in the Department of Physical Medicine and Rehabilitation at the University of North Carolina School of Medicine.
With his wife, Cheryl Yanuck, MD, a psychiatrist, Dr. Yanuck runs the Yanuck Center for Life and Health, a functional medicine clinic in Chapel Hill, North Carolina. His practice is primarily focused on the care of patients with autoimmune disease, chronic infection, persistent inflammatory process, chronic GI disorders, or other immunologically involved challenges. Dr. Yanuck also provides online consultations for clinicians.
Cogence Immunology is the creation of Dr. Yanuck the company’s CEO and Director of Education. Dr. Yanuck began studying immunology in 2001, after he observed that focusing on specific patterns in immune function could profoundly influence the outcomes of challenging cases. The more he learned, the better the outcomes became. Cogence® Immunology reflects Dr. Yanuck’s more than two decades of immunology study and clinical experience.
Dr. Yanuck has published a number of research papers in peer-reviewed medical journals on topics related to functional immunology, including neurological, inflammatory, infectious and autoimmune disorders as well as the cancer immune microenvironment.
Guest websites and links:
https://cogenceimmunology.com
Selection of our guest’s publications:
- Yanuck SF. Failed Induction of the TH1 System in TH2 Dominant Patients: The Cancer-Permissive Immune Macroenvironment. Integr Med (Encinitas). 2024 May;23(2):24-35.
- Yanuck SF, Pizzorno J, Messier H, Fitzgerald KN. Evidence Supporting a Phased Immuno-physiological Approach to COVID-19 From Prevention Through Recovery. Integr Med (Encinitas). 2020;19(Suppl 1):8-35.
- Yanuck SF. Microglial Phagocytosis of Neurons: Diminishing Neuronal Loss in Traumatic, Infectious, Inflammatory, and Autoimmune CNS Disorders. Front Psychiatry. 2019 Oct 3;10:712.