The Peptide Podcast
In today’s episode we’ll talk about L-Carnitine. What is L-carnitine, what does it do, and why are more people choosing to inject it instead of taking it as a pill? Let’s break it down. L-carnitine is a compound made from the amino acids lysine and methionine, and its main job is helping your body turn fat into energy by shuttling fatty acids into your cells’ mitochondria. While we naturally make some and get more from foods like red meat and dairy, certain people — like athletes, older adults, or those with metabolic issues — may not make or absorb enough. That’s...
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Today we’re diving into Pinealon, a bioregulatory peptide with promising effects on brain health, cognition, and aging. We’ll cover what it is, how it works, its benefits, origins, potential side effects, and how to it with other peptides like . What Are Bioregulator Peptides? Let’s start with the basics. Bioregulator peptides are short chains of — usually just 2 to 4 — that act as gene switches. Think of them as precision tools your body uses to fine-tune organ and tissue function at the cellular level. These peptides were originally discovered by Russian researchers in the...
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Today we’re diving into how to source safely. We’ll talk about why where you live matters, how to find a reputable provider, and the red flags to watch out for. So if you’ve been curious about peptides but unsure where to start, this podcast is for you. Why Peptides? And Why You Need to Be Cautious So first, what are peptides? In short, they're short chains of amino acids—basically, the building blocks of proteins—that signal your body to perform specific actions. Some stimulate , others help with , , or . Sounds amazing, right? And they can be. But, only when used...
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Today we’re tackling one of the biggest myths in modern nutrition: the idea that we need to restrict our daily sodium intake. For years, we’ve been led to believe that salt is the bad guy—linked to high blood pressure, heart disease, and a shorter lifespan. But that’s just not the case. Today, we’re diving into why salt isn’t the villain it’s made out to be—in fact, it’s essential, especially if you follow a low-carb, ketogenic, or Paleo diet, or if you’re using popular like . We’ll also spotlight a product that’s getting it right: LMNT, an electrolyte drink mix that...
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So, you've heard the rumors—“GLP-1s destroy your muscle!” But… is that actually true? Think again. Today, we’re setting the record straight. If you're serious about real, healthy weight loss—and actually keeping your strength for the long haul—this episode is a must. We’re diving into a long-overdue conversation about GLP-1 medications, metabolism, body composition, and what’s really happening to your muscle mass on these meds. Because weight loss isn’t just about the scale—it’s about how you lose it. Let’s get into it. Quick Basics — What Are GLP-1 and GIP/GLP-1...
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Today, we’re talking about how and peptides like (See-max) and (SEH-lank) work together to support cognitive health, improve focus, and reduce mental fatigue. Let’s start with nootropics. These are substances that are designed to support and enhance mental performance. Some work by improving memory, others help with focus, alertness, or reducing brain fog. Nootropics can be: Natural, like L-theanine or Lion’s Mane Nutraceuticals, like Alpha-GPC or CDP-Choline, which support neurotransmitter production Or synthetic, like or racetams “RASS-uh-tams”, which are often...
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Hey, welcome back! Today, we’re diving into something that can seriously up your game when it comes to energy, performance, and even longevity—NAD+. If you haven’t heard of it, don’t worry, we’ve got you covered. We’re also going to talk about some awesome peptide stacks that can keep you feeling energized and performing at your best—whether that’s crushing it in your workouts or staying sharp through your workday grind. So, if you’re looking to boost your fitness, stay more focused at work, or just feel more energized in general, this episode’s for you. What is NAD+?...
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Today, we're talking about a hot topic in the world of fitness and wellness: peptide stacking. Whether you're looking to build lean muscle, burn fat, enhance recovery, or boost cognitive function, peptide stacking could be a game-changer. But, just like anything, it’s important to know the ins and outs of how it works and how to “stack” safely. What is Peptide Stacking? So, what is peptide stacking, and how can it benefit you? Let’s break it down. At its core, peptide stacking refers to the practice of combining different to maximize their individual effects and synergize their...
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Today, we’re venturing into a topic that many of us might not think about — parasite and worm infections. These unseen invaders can wreak havoc on your health, yet often go unnoticed for a long time. And, despite all the supplements and we might be using to optimize our health, we may still be missing something very important: a potential parasite or worm infection. In this episode, we’ll explore the signs and symptoms of these infections, how you can acquire them, and why we should consider them even if we’re doing everything "right" in terms of diet and wellness. Let’s get...
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Today we’re going to talk about something that could be a game-changer for anyone looking to support their eye health: Visoluten, the retinal bioregulator peptide. Bioregulator peptides like Visoluten are gaining attention in the field of regenerative medicine due to their ability to target specific organs or systems in a highly focused and natural way, supporting the body’s inherent healing processes. So, whether you're someone who’s noticing some age-related vision changes, or you're just keen on taking better care of your eyes, stick around because this episode is for you. What...
info_outlineSomeone might switch from semaglutide to tirzepatide to achieve greater weight loss or improve blood sugar control. Tirzepatide has been shown to be more effective for some people because it works on two different hormones, GLP-1 and GIP. This combination can lead to better results in managing weight and overall health.
Additionally, if a person stops losing weight on semaglutide or isn't feeling as much appetite suppression, switching to tirzepatide could provide a new option, especially at higher doses.
In this podcast, we’ll discuss the feedback from doctors and patients about switching from semaglutide to tirzepatide for weight loss. The experiences shared are quite varied. Here are some common themes based on what healthcare providers and patients reported.
1. Appetite Suppression
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Patients' Experiences:
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Some patients report weaker appetite suppression with tirzepatide compared to semaglutide. They mention that they felt more consistently full or experienced less "food noise" (persistent thoughts about food) with semaglutide.
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Others find tirzepatide equally or more effective at reducing hunger, especially at higher doses (10 mg to 15 mg). They note that their appetite was well-controlled after titrating to these higher doses.
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Clinicians' Observations:
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Many clinicians observe that tirzepatide’s appetite suppression is dose-dependent, with lower doses (5 mg) sometimes being less effective than semaglutide 2.4 mg, but higher doses (7.5 mg and up) providing stronger suppression.
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Some clinics report that patients may need more time on tirzepatide for the full appetite-suppressing effects to become noticeable.
2. Weight Loss:
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Patients' Experiences:
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Many patients experience greater or more rapid weight loss with tirzepatide, especially when titrated to higher doses (10 mg or more). Some report that they plateaued with semaglutide but started losing more weight after switching to tirzepatide.
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Others find that their weight loss slows down after switching to tirzepatide, particularly if their tirzepatide dose starts low (e.g., 2.5 or 5 mg), which may take time to match the effects of semaglutide 2.4 mg.
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Clinicians' Observations:
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Physicians often report that tirzepatide tends to lead to greater weight loss overall compared to semaglutide, especially when patients reach the higher doses (15 mg).
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However, individual variability plays a significant role, with some patients responding better to one medication over the other, depending on their metabolic profile and personal response to the medications.
3. Side Effects:
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Patients' Experiences:
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Patients commonly note that tirzepatide's side effects are similar to semaglutide, particularly stomach-related symptoms like nausea, vomiting, and diarrhea. However, these effects tend to lessen over time with both medications.
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On the other hand, some patients may experience more intense side effects with tirzepatide, especially during the titration phase.
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Clinicians' Observations:
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Clinics generally find that tirzepatide’s tolerability improves when the dose is titrated slowly, starting at 2.5 mg. Jumping directly to higher doses (5 mg or more) can increase the likelihood of nausea and other stomach-related side effects.
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Long-term side effect profiles are comparable between the two, but some clinics observe that tirzepatide's dual mechanism (GIP + GLP-1) might cause more initial stomach discomfort in certain patients.
4. Patient Preferences:
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Some patients prefer staying on semaglutide because it effectively curbs their hunger and controls cravings better, even if tirzepatide provides more weight loss.
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Others favor tirzepatide due to its better results in weight loss and overall improvements in metabolic health, especially once they reach higher doses.
Thanks again for listening to The Peptide Podcast. We love having you as part of our community. If you love this podcast, please share it with your friends and family on social media, and have a happy, healthy week!
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