30 - PATHFINDER 2 study results from ESMO 2025 with principal investigator Nima Nabavizadeh, MD
The Cancer SIGNAL
In this episode of The Cancer SIGNAL, Nima Nabavizadeh, MD, an associate professor of radiation medicine at Oregon Health & Science University (OHSU) and the chief medical officer at the Cancer Early Detection Advanced Research Center (CEDAR) at OHSU, joins host Susanna Quinn to share the results from the groundbreaking GRAIL PATHFINDER 2 clinical trial unveiled at the European Society for Medical Oncology (ESMO 2025) Congress. As the principal investigator for the trial, which examined the safety and performance of the Galleri multi-cancer early detection test, Dr. Nabavizadeh...
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29 – The Dallas Cowboys Are Detecting Cancer Early
The Cancer SIGNAL
In this episode of The Cancer SIGNAL, Tad Carper, Senior VP of Communications for the Dallas Cowboys, shares how a multi-cancer early detection (MCED) screening unexpectedly revealed a cancer signal for head and neck cancer—despite experiencing no symptoms. The test, sponsored for the team’s assistant coaches by quarterback Dak Prescott’s foundation, Faith Fight Finish, was the first step toward Tad’s stage two cancer diagnosis. Tad reflects on the emotional and mental impact of his diagnosis, the importance of early detection, and how the experience reshaped his...
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28 – Jack’s Journey with Multi-Cancer Early Detection
The Cancer SIGNAL
At a semiannual primary care visit, Jack’s doctor mentioned multi-cancer early detection (MCED) testing. Though Jack wasn’t experiencing symptoms, and has no family history of cancer, he decided to take the test. Two Cancer Signal Detected results from MCED screening tests taken six months apart helped his care team determine the necessary diagnostics that confirmed an early-stage cancer diagnosis. Listen to Jack’s story to learn more about the impact early cancer detection had on his life. Watch the full episode on YouTube: Help shape future episodes by taking our...
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27 – Multi-Cancer Early Cancer Detection at the Doctor’s Office
The Cancer SIGNAL
Dr. Patrick McGill was instrumental in introducing Community Health Network to multi-cancer early detection (MCED) testing and integrating it into routine screenings offered to patients. Dr. McGill is Executive Vice President and Chief Transformation Officer at Community Health Network, and as a practicing primary care physician he believes strongly in the importance of catching cancer as early as possible to improve outcomes for patients. In this episode he shares how MCED has made an impact at Community Health Network. Watch the full episode on YouTube: Help shape future...
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26 – The Role of Cancer Screening in Longevity
The Cancer SIGNAL
How does cancer screening fit into one’s longevity goals? Dr. Ummat, a preventative medicine physician dedicated to changing the approach to aging, shares insights on the role of preventative care in maintaining long-term health, why proactive screening matters, and how new technologies like multi-cancer early detection testing can change the way we screen for cancer. Watch the full episode on YouTube: Help shape future episodes by taking our survey: Transcripts: Sign up for GRAIL’s newsletter: The Galleri test does not detect a signal for all cancers. Not all...
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25 – Research Update on Multi-Cancer Early Detection with Dr. Eric Klein
The Cancer SIGNAL
Dr. Eric Klein, Distinguished Scientist at GRAIL, provides a research update from GRAIL’s 2024 findings on multi-cancer early detection (MCED) testing, presented at ASCO, ESMO, AACR and more. He explores insights from the first real-world evaluation of repeat multi-cancer early detection testing, data on how multi-cancer early detection (MCED) testing is helping cancer survivors by detecting recurrence and new cancers, and findings on using MCED to detect high grade, clinically significant prostate cancer over indolent cases. Plus, the economic and emotional impacts of cancer screening, and...
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24 – Rich and Staci’s Story with Multi-Cancer Early Detection
The Cancer SIGNAL
At their doctor’s recommendation, Rich and Staci each took a multi-cancer early detection test during a routine checkup. Despite having no symptoms, Rich received a Cancer Signal Detected result, while Staci, who had a strong family history of cancer, did not. Listen to their story and learn about the impact of early cancer detection. Watch the full episode on YouTube: View Rich and Staci’s story: Help shape future episodes by taking our survey: Transcripts: Sign up for GRAIL’s newsletter: The Galleri test does not detect a signal for all cancers....
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23 – Early Detection = Better Outcomes, with the Prevent Cancer Foundation
The Cancer SIGNAL
Seven in 10 Americans are behind on at least one routine cancer screening. Jody Hoyos, CEO of the Prevent Cancer Foundation, joins Susanna to discuss the critical role of early cancer detection. She addresses the most common misconceptions about cancer screening and explains the importance of proactive screening, even when no symptoms are present. Help shape future episodes by taking our survey: Transcripts: Sign up for GRAIL’s newsletter:
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22 – Meet Susanna Quinn, Ovarian Cancer Survivor and Our New Host
The Cancer SIGNAL
Introducing our new host, Susanna Quinn! Susanna is a cancer survivor, entrepreneur, writer and philanthropist. Diagnosed with stage three ovarian cancer in 2019, Susanna underwent aggressive treatment and achieved cancer-free status by September of the same year. In this episode, Kim Thiboldeaux, the Cancer SIGNAL’s inaugural host, interviews Susanna about her cancer story and passes the torch. Help shape future episodes by taking our survey: Transcripts: Sign up for GRAIL’s newsletter:
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21 – Overcoming Medical Mistrust, Bias, and Access to Cancer Screening in the LGBTQ+ Community
The Cancer SIGNAL
Dr. Scout, Executive Director of the National LGBT Cancer Network, discusses how the LGBTQ+ community faces unique challenges in cancer screening. Dr. Scout highlights the increased cancer risks due to social factors, like discrimination and medical mistrust, and emphasizes the importance of inclusive healthcare provider training. The National LGBT Cancer Network works to educate both the community and providers, runs support groups for LGBTQ+ cancer survivors, and is developing a more comprehensive list of welcoming providers. Help shape future episodes by taking our survey:...
info_outlineStep into the lab with Rita Shaknovich, vice president of medical affairs and head of clinical laboratories at GRAIL, as she dives into the science behind the Galleri test and brings to life the process that a Galleri test sample goes through from beginning to end.