Antimicrobial Resistance in Neisseria Gonorrhoeae (JCM ed.)
Release Date: 12/05/2023
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Multidrug-resistant Gram-negative infections remain one of the most urgent public health challenges worldwide, with some infections approaching the limits of available treatment options. In this special edition of Editors in Conversation, we celebrate the remarkable 10-year tenure of Dr. Laurent Poirel, whose pioneering work has profoundly shaped our understanding of antimicrobial resistance. Through his unique perspective, we will explore the evolving landscape of resistance in Gram-negative organisms, reflect on the major advances and challenges of the past decade, and discuss what the...
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Technology and Discovery in Modern Microbiology
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It starts out with a couple of stomach twinges, maybe a little nausea, maybe some sharp pains, and then… before you know it, you are running to the closest toilet with which you become very, very familiar. Cyclospora causes frequent watery diarrhea with sometime “explosive” bowel movements, but is typically a relatively rare cause of infectious diarrhea. However, the U.S. is in the midst of one of the largest documented cyclosporiasis outbreaks. How does one acquire this parasite? What are the risks? And – most importantly for our audience – how does the lab approach diagnosis?...
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Next Gen Careers in Clinical Microbiology
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Artificial intelligence is revolutionizing the world in many ways. One of the most exciting applications of artificial intelligence is in the area of drug discovery. Particularly the discovery of antimicrobial molecules that are in the environment or even hidden within our own body. Today, we discuss some of the uses of artificial intelligence in the discovery of antimicrobials with an outstanding expert in the field. Topics discussed: How artificial intelligence can help the discovery of new antimicrobial moieties Antibiotic discovery and challenges to bring molecules to the clinic The...
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Phage JS1: The Virus Breaking the Rules
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Harnessing MALDI-TOF for MICs
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info_outlineGonorrhea remains one of the more common sexually transmitted infections. In North America, the number of reported cases has generally risen for over ten years, with interruptions in the early days of the COVID-19 pandemic, followed by returns to rising rates of infection. Under the selective pressure of antimicrobial treatment, antimicrobial resistance has risen, which has led to limited options for treatment
Today, we will be discussing antimicrobial resistance in N. gonorrhoeae, including these questions:
• How accurate is gradient diffusion susceptibility testing when compared to agar-dilution results?
• Should we use analysis of whole genome sequencing results or agar dilution phenotypic results as the gold-standard for antibiotic susceptibility testing of N. gonorrhoeae?
• What is the utility of beta-lactamase testing for predicting penicillin susceptibility results in N. gonorrhoeae?
Guests:
- Dr. Tanis Dingle, Clinical Microbiologist at Alberta Precision Laboratories and a Clinical Associate Professor in the Department of Pathology and Laboratory Medicine at the University of Calgary.
- Dr. Angela Ma., Clinical Microbiologist at Public Health Ontario.
Link:
This episode of Editors in Conversation is brought to you by the Journal of Clinical Microbiology and hosted by JCM Editor in Chief, Alex McAdam and Dr. Elli Theel. JCM is available at https://jcm.asm.org and on https://twitter.com/JClinMicro.
Visit journals.asm.org/journal/jcm to read articles and/or submit a manuscript.