Gram-Negative Resistance: A Decade of Evolution with Laurent Poirel, Ph.D.
Editors in Conversation
Multidrug-resistant Gram-negative infections remain one of the most urgent public health challenges worldwide, with some infections approaching the limits of available treatment options. In this special edition of Editors in Conversation, we celebrate the remarkable 10-year tenure of Dr. Laurent Poirel, whose pioneering work has profoundly shaped our understanding of antimicrobial resistance. Through his unique perspective, we will explore the evolving landscape of resistance in Gram-negative organisms, reflect on the major advances and challenges of the past decade, and discuss what the...
info_outline
Technology and Discovery in Modern Microbiology
Editors in Conversation
New imaging and measurement approaches are revealing previously hidden aspects of microbial life, challenging long-held assumptions and creating opportunities to answer questions that were once out of reach. Marvin Whiteley, Heran Darwin and Jeffrey Moffitt talk about how technological innovation is transforming microbiology. Guests: - NYU Grossman School of Medicine - Boston Children's Research This episode of Editors in Conversation is brought to you by mBio® and hosted by mBio Editor in Chief, Marvin Whiteley, Ph.D. Visit to read articles and/or submit a manuscript. Receive up...
info_outline
Cyclospora In The Lab
Editors in Conversation
It starts out with a couple of stomach twinges, maybe a little nausea, maybe some sharp pains, and then… before you know it, you are running to the closest toilet with which you become very, very familiar. Cyclospora causes frequent watery diarrhea with sometime “explosive” bowel movements, but is typically a relatively rare cause of infectious diarrhea. However, the U.S. is in the midst of one of the largest documented cyclosporiasis outbreaks. How does one acquire this parasite? What are the risks? And – most importantly for our audience – how does the lab approach diagnosis?...
info_outline
Next Gen Careers in Clinical Microbiology
Editors in Conversation
So, you think you want a career in clinical microbiology? This field demands more than technical skill—it’s driven by curiosity, growth, and the confidence to lead. From mastering diagnostics to pushing innovation and mentoring the next generation, success comes to those who keep evolving. In this episode, we explore the many paths into the field—and spotlight the Laboratory Director role through a candid conversation between early- and mid-career leaders, sharing the real highs, lows, and advice for those ready to step up. Watch this episode: Guests: Amanda Roth, Ph.D. Janiece Glover,...
info_outline
AI and Antibiotic Discovery
Editors in Conversation
Artificial intelligence is revolutionizing the world in many ways. One of the most exciting applications of artificial intelligence is in the area of drug discovery. Particularly the discovery of antimicrobial molecules that are in the environment or even hidden within our own body. Today, we discuss some of the uses of artificial intelligence in the discovery of antimicrobials with an outstanding expert in the field. Topics discussed: How artificial intelligence can help the discovery of new antimicrobial moieties Antibiotic discovery and challenges to bring molecules to the clinic The...
info_outline
Why Your Lab QC Might Be Missing Critical Errors
Editors in Conversation
Accurate AST results are the backbone of diagnostic stewardship, yet routine quality control (QC) might be missing subtle shifts that skew your hospital’s annual antibiogram. By examining a real-world "silent failure" in daptomycin testing, we explore how lab-driven data is essential to the AMR crisis response and why the human eye—and traditional QC bugs—aren't always enough to catch technical drifts. This session breaks down the importance of LIS rules, alert fatigue, and the future of automated susceptibility testing. Guests: Laurel J. Glaser, M.D., Ph.D. Rebekah Dumm, Ph.D. D(ABMM) ...
info_outline
Phage JS1: The Virus Breaking the Rules
Editors in Conversation
In this episode, a fascinating new bacteriophage, JS1. While most contractile phages (which inject DNA like a spring-loaded syringe) are rigid and straight, JS1 sports a curved, flexible tail that may help it navigate the complex "canyons and valleys" of the bacterial cell wall. Watch this episode: https://youtu.be/eDGta8xc4_0 Guests: Sabrina Suhani, Ph.D., Graduate Student, Monash University, Australia Trevor Lithgow, Ph.D., Professor, Monash University’s Biomedical Discovery Institute. Links: with a tail that is both curved and contractile This episode of Editors in Conversation...
info_outline
Urine-based Testing to Detect HPV
Editors in Conversation
Is the future of cervical cancer screening non-invasive? Sharmila Manjeshwar, Ph.D. and Jeffrey Klausner M.D. MPH, discuss a breakthrough in HPV diagnostics: urine-based testing. While vaccination and clinical screening have reduced cervical cancer rates, participation has stalled due to barriers like healthcare access and the invasive nature of traditional clinician-collected samples. This conversation explores how novel high-volume urine concentration technology is changing the landscape, making screening more accessible, private, and efficient. Watch this episode:...
info_outline
The Aerobiome - The Hidden Biology of Air
Editors in Conversation
Most microbiome research focuses on soil, oceans, or hosts. But the atmosphere itself harbors diverse communities of bacteria and fungi that move between ecosystems. This episode explores a recent mBio study comparing airborne microbial communities above a subalpine forest and a grassland in Colorado. The conversation unpacks what the “aerobiome” is, how scientists actually sample microbes from the air, and why height, time of day, and season matter. The study reveals striking differences between fungi and bacteria, with fungi showing strong site-specific structure and environmental...
info_outline
Harnessing MALDI-TOF for MICs
Editors in Conversation
Matrix-assisted laser desorption ionization time of flight mass spectrometry (or MALDI) has revolutionized the clinical microbiology laboratory, enabling rapid, accurate and cheap identification of bacteria, yeast, moulds and mycobacteria. In most labs, it has become a verb (I maldi’ed it). But – can it replace our antimicrobial susceptibility tests? Let’s find out! Guests: Dr. Frieder Schaumburg Niklas Wiesmann
info_outlinePicture this, you wake up one morning with nausea, body aches, abdominal pain, and despite sleeping all night, you are exhausted. You then find yourself running to the restroom with watery and somewhat explosive diarrhea. You think to yourself – what could this be? Well, if the year was 2023, in the summer and you happen to live in Texas, chances were somewhat high that you had probably had cyclosporiasis. And today, we are going to talk about this particular parasite and focus in on what our options are for detecting it given that it is not routinely picked up on O&P exams. And while there are molecular panels out there that include Cyclospora as a target, as our speakers will share, there is an easier and cheaper approach we can consider to quickly ID this pathogen.
Guests:
- Dr. Angela Ma. Public Health Ontario and Assistant Professor at the University of Toronto
- Dr. Marc Couturier. Drector of the clinical microbiology lab at NorDx lab at MaineHealth in Scarborough, Maine
Links:
- Shedding new light on Cyclospora: how the use of ultraviolet fluorescence microscopy can improve diagnosis of cyclosporiasis
- Join ASM for up to 50% off the publication fees when you publish in JCM or any of the ASM journals.
- Attend ASM Microbe
This episode of Editors in Conversation is brought to you by the Journal of Clinical Microbiology and hosted by JCM Editor in Chief, Alex McAdam and Dr. Elli Theel. JCM is available at https://jcm.asm.org and on https://twitter.com/JClinMicro.
Visit journals.asm.org/journal/jcm to read articles and/or submit a manuscript.