E166 - Biologic therapies for severe asthma with persistent type 2 inflammation
Release Date: 06/24/2024
Australian Prescriber Podcast
Dhineli Perera chats with Allen Cheng, director of Infectious Diseases at Monash Health and member of the Antibiotic Expert Group, about some of the updates in the latest version of Therapeutic Guidelines: Antibiotic. Allen talks about changes to severity assessment and treatment for community-acquired pneumonia, updated antimicrobial dosing advice, a new tiered approach for managing patients with sepsis and much more.
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Jo Cheah talks to Bronwyn Jenkins, consultant neurologist, about the role of calcitonin gene-related peptide (CGRP)–targeted therapies in migraine treatment. Bronwyn explains the difference between tension-type headaches and migraines, and outlines current treatment options. The conversation also covers adverse effects, patient eligibility, and other important considerations for prescribers. Read the in Australian Prescriber.
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Justin Coleman speaks with Kate Ziser, a pharmacist at the Princess Alexandra Hospital in Brisbane, about her paper on the role of triple antithrombotic therapy in patients with atrial fibrillation following coronary stent insertion. Kate explains when triple therapy is indicated, the duration of therapy, and the step-down approach to antithrombotic therapy. Read the by Kate and her co-authors in Australian Prescriber.
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Laura Beaton chats with Nadia Mouchaileh, senior pharmacist, and Jillian Cameron, head of movement disorders and consultant neurologist at Austin Health, about device-assisted therapies for Parkinson disease. They discuss the benefits vs traditional therapies, when to refer patients to a specialised movement disorder centre and what to look for when caring for a patient using a device. Read the in Australian Prescriber.
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Jo Cheah talks to Debra Kennedy, director of MotherSafe, about her paper on drug safety in pregnancy. Debra discusses the key considerations when stopping or starting a medicine during pregnancy, and the ways in which medicines can affect developing fetuses. Debra also explains the Australian categorisation system for prescribing medicines in pregnancy. Read the by Debra and her co-author, Ronald Batagol, in Australian Prescriber.
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Dhineli Perera speaks with Lee Fong, a medical advisor for the Australian Commission on Safety and Quality in Health Care, about the need to establish a national clinical care standard for people with chronic obstructive pulmonary disease (COPD). Lee explains how the Standard can be used to identify gaps in care and optimise the management of patients with COPD. Read the by Lee and his co-authors in Australian Prescriber.
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David Liew talks to Claire Larter, a medical officer at the pharmacovigilance branch of the TGA, about her paper on adverse event reporting. Claire explains why pharmacovigilance is important for clinicians, and outlines what type of adverse events should be reported. The conversation also covers the process of reporting adverse events and how the TGA handles reports. Read the by Claire and her co-authors in Australian Prescriber.
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Laura Beaton chats with Paul Kubler, director of Rheumatology at Royal Brisbane and Women’s hospital, about how to identify and manage antiphospholipid syndrome. They discuss the key presentations of APS, classification criteria and approaches to treatment. They also cover patients with catastrophic APS and asymptomatic people with persistent antiphospholipid antibodies. Read the by Paul and his co-authors in Australian Prescriber.
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Jo Cheah talks with Eileen Cole, GP lead, and Jennifer Kyi, pharmacist advisor at Quit, about the use of therapeutic vapes for smoking cessation. They discuss the current evidence and new Australian guidelines. The conversation also covers choosing a vape and how to prescribe or supply vapes. Read the by Eileen, Jennifer, and their co-authors, in Australian Prescriber.
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In this episode Dhineli Perera speaks to John Turnidge, who leads the national surveillance program for Antimicrobial Use and Resistance in Australia. They discuss the significant impact of the pandemic on reducing antibiotic use in the community, and how this benefit can be sustained and improved on. Read the by John and his co-authors, Carolyn Hullick and Kim Stewart, in Australian Prescriber.
info_outlineJo Cheah speaks to Peter Wark about his article on biologic therapies for severe asthma with persistent type 2 inflammation. Peter explains the difference between difficult and severe asthma and how to test for persistent type 2 inflammation. He also runs through the available biologics and when and how they are used. Read the full article by Peter and his co-author, Sahan Chandrasekara, in Australian Prescriber.