Biopharma EHS Podcast - Episode 29 Comparison of PDE Values (AI Generated)
Biopharma EHS
This episode is a test use case where you can take a very technical scientific document and upload to a large language model to create a two-host podcast. The results were amazing.
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Biopharma EHS Podcast Episode 28 - PDE reports
Biopharma EHS
In this episode, Dean Calhoun of Affygility Solutions discusses top 10 mistakes & tricks used by cheap providers of PDE reports.
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Biopharma EH&S podcast episode #27
Biopharma EHS
Interview with Mark Cunningham-Hill where we will discuss the coronavirus and precautions that business travelers should take and other precautions in general when traveling on business internationally.
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Biopharma EHS Podcast Episode 26
Biopharma EHS
In this episode, Dean Calhoun of Affygility Solutions interviews Dave Eherts, Vice President of Global EHS for Allergan. In this 25 minute interview we discuss a wide variety of EH&S issues that Dave was involved in over his 30+ years in EHS. These issues include managing the financial aspects of EHS, potent compound safety and the challenges with occupational exposure limits for pharmaceuticals, and other career advice for EH&S professionals.
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Jul 20 2017 Flashing Briefing
Biopharma EHS
For July 20, 2017. Artificial Intelligence is about to play a major role in the pharmaceutical industry. On July 2nd of this year, Glaxo-Smith-Kline revealed a 43-million dollar deal in which they will use A.I. to make the process of discovering new drugs easier. The goal is to reduce the time it takes from identifying a target for disease intervention to finding a molecule that acts against it. He hopes to bring it from an average 5 and a half years today to just one year in the very near future.
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BioPharma EHS Podcast Episode 25
Biopharma EHS
Occupational Toxicology and Occupational Medicine - Where are they the same and where are they different? In this episode of the BioPharma EHS Podcast, Dean M. Calhoun, President and CEO of Affygility Solutions hosts a discussion between Dr. Mark Cunningham-Hill, President of Worldwide Health Consulting LLC and Dr. Frank Richardson, Principal Toxicologist for LLC. The discussion starts out covering the basic elements of an occupational medicine program and the unique challenges posed by the pharmaceutical industry in which occupational exposure to potent compounds can cause adverse effects in...
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Biopharma EHS Podcast Episode #24
Biopharma EHS
In Episode #24 of the Biopharma EHS podcast, Dean M. Calhoun, CIH discusses with Dr. Joe Nieusma, Senior Occupational Toxicologist for Affygility Solutions, the "Mystery of Cytotoxic Compounds." For multi-product pharmaceutical manufacturing facilities, this often a controversial topic since many people believe that cytotoxic compounds require dedicated facilities or equipment. It is also a topic of debate when setting occupational exposure limits and acceptable daily exposure values for active pharmaceutical ingredients.
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Biopharma EHS Podcast Episode #23
Biopharma EHS
In this episode of the Biopharma EHS podcast, Dean M. Calhoun, CIH, President and CEO of Affygility Solutions interviews Kevin Rosenthal of . During the interview we discuss handling potent compounds, , and occupational control banding.
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Risk-MaPP, ADEs, and PDEs: Their importance to multi-product pharmaceutical manufacturing facilities
Biopharma EHS
In this episode of the Biopharma EHS Podcast, Dean M. Calhoun, CIH, President and CEO of , interviews Ms. Stephanie Wilkins, President of , on the subject of Risk-MaPP, ADEs and PDEs: Their importance to multi-product pharmaceutical manufacturing facilities. Risk-MaPP stands for Risk-Based Manufacture of Pharmaceutical Products. It is one of the International Society of Pharmaceutical Engineers' (ISPE) Base-line Guides. One of the essential components of Risk-MaPP is the determination of acceptable daily exposure (ADE) values. Calculation of ADEs is similar to the calculation of PDEs presented...
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Biopharma EHS Podcast Episode No. 20
Biopharma EHS
BioPharma EH&S Podcast Episode No. 20...
info_outlineContainment Validation and Surrogate Monitoring
In this episode of the Biopharma EHS podcast, Dean M. Calhoun, CIH, President and CEO of Affygility Solutions discusses the following topics:
- A review of Episode no. 16 of the Biopharma EHS podcast. In that episode, Dean M. Calhoun, President and CEO of Affygility Solutions, and Dr. Joe Nieusma, Sr. Occupational Toxicologist with Affygility Solutions discuss Category 4 and 5 potent compounds. Our discussions include what factors determine a Category 4 or 5 potent compound, why the occupational exposure limit (OEL) alone is not enough to determine if a specific compound falls into a category 4 or 5 control band, and specific examples of potent compounds that are classified into these control bands.
- An interview with Matt Meiners, Division Manager, Laboratory Services for the Bureau Veritas, Lake Zurich, Industrial Hygiene Laboratory. In this interview, Dean and Matt discuss containment validation and surrogate monitoring. Often call SMEPAC testing. Matt provides insight into why containment validation is necessary, the advantages and disadvantages of different surrogate compounds, the sensitivity of their industrial hygiene laboratory methods for surrogate compounds, the advantages and disadvantages of the total dust versus the Institute of Occupational Medicine (IOM) method of sampling.
- Upcoming events and happenings of interest to environmental, health and safety professionals in the biotechnology, pharmaceutical, and medical device industries. These events include:
- Affygility Solutions' webinars. These webinars include:
- Advance Topics in Potent Compound Safety
- Dermal Exposure and Absorption of Active Pharmaceutical Ingredients
- Isoflurane Safety
- Society of Toxicology Annual Meeting in San Francisco, CA
- Society of Chemical Hazard Communication Spring Meeting in Nashville, TN
- The above webinars are a great way for environmental, health and safety professionals to obtain certification maintenance points.
If you have questions regarding this podcast, please email podcast @ affygility.com