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124 Depression: When Medication Doesn't Work

Critically Speaking

Release Date: 09/08/2021

Dr. David Hill: Peanut and Food Allergies in Children show art Dr. David Hill: Peanut and Food Allergies in Children

Critically Speaking

In this episode, Therese Markow and Dr. David Hill discuss the rise of peanut allergies in children. David explains that anaphylaxis, a severe allergic reaction, is common in children, often triggered by food. He emphasizes the importance of early allergen introduction to prevent allergies. The LEAP study from 2015 showed that introducing peanuts before six months reduces the risk of peanut allergy. They also discuss other common allergies and the fact that many children outgrow milk and egg allergies by age four.     Key Takeaways: The major allergens are milk, egg, soy,...

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In this episode, Therese Markow and Dr. Kari Nadeau discuss the presence and health effects of microplastics in our bodies. Microplastics can enter our bodies through various environmental routes, including food, water, and air. They are in everyone’s bodies to some degree.  Microplastics have been linked to health issues like stroke, cancer, and heart attacks. Simple actions like avoiding single-use plastics and processed foods can reduce microplastic levels in the blood by up to 80% in three months. Dr. Nadeau emphasizes the need for further research and consumer awareness to mitigate...

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In this episode, Therese Markow and Dr. Lise Eliot discuss neurosexism and brain differences between males and females. Dr. Eliot explains that historical brain comparisons often aimed to prove women's inferiority, citing examples like weighing cadaver brains. Modern MRI studies show minor structural differences, but still present significant methodological challenges. She highlights that brain plasticity and social experiences shape gender differences, noting that women tend to have more active default mode networks, linked to anxiety and rumination. She emphasizes that gender is a...

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In this episode, Therese Markow, Dr. Catherine Lebel, and Dr. Sam Nivins discuss the impact of prenatal factors on fetal brain development. Catherine explains how MRI can detect subtle brain changes due to prenatal alcohol exposure, even at low levels, and emphasizes the importance of avoiding alcohol during pregnancy. Sam discusses the effects of maternal obesity before pregnancy on brain development, noting sex-specific differences and the importance of early intervention. Both also touch on the impact of stressors, such as natural disasters, and the need for early identification and support...

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Critically Speaking

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Critically Speaking

In this episode, Therese Markow and Dr. Tami Rowen discuss the listener questions that arose from her last episode on Critically Speaking. From drinking soy milk as a substitute for estrogen, the complex relationship between the number of children you have and breast cancer risk, dense breast tissue, early menstruation, hormone replacement therapy, and more. Listen in for the answers to your questions!    Key Takeaways: Soy is not in any way a substitute for estrogen. How it affects your circulating estrogens depends on your age. While the number of kids you have is inconclusive...

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More Episodes

Dr. Therese Markow talks with psychiatrist and researcher Dr. Daniel Blumberger about depression that does not respond to medications and behavioral cognitive therapy.  Approximately one third of patients suffering from major depression are “Treatment Resistant”.

Fortunately, there are a range of brain stimulation techniques that help the majority of these patients. Electroconvulsive therapy or ETC, has evolved into a much more benign procedure than depicted earlier in movies and has the best outcomes in patients with major depression.  New techniques, involving stimulation of the brain magnetically, such as Transcranial Magnetic Stimulation (TMS) also can be effective and are being refined for broader use.  Depression is a serious and sometimes fatal disease, and there is hope for those resistant to pharmaceutical approaches.

 

 

 Key Takeaways:

  • Major Depressive Disorder, or MDD, is a debilitating disorder that can be fatal
  • About a third of those suffering from MDD, do not respond to. pharmaceutical treatments.
  • The majority of these patients benefit from ECT, which now has been greatly improved.
  • A newer group of brain treatments, using magnetic stimulation, also are useful for Treatment Resistant Depression.
  • Sufferers should ask their physicians about access to these non-pharmaceutical treatments.

 

 

"It is very important to intervene early when someone isn’t responding to medication. The more treatments that someone doesn’t respond to, the less likely that they will respond to each subsequent course of treatment. The longer things linger, the harder it is to get someone better." —  Dr. Daniel Blumberger

 

Connect with Dr. Daniel Blumberger:

CAMH Profile: Dr. Daniel Blumberger  

 

 

Connect with Therese:

Website:   www.criticallyspeaking.net

Twitter: @CritiSpeak

Email: theresemarkow@criticallyspeaking.net

 

 

Audio production by Turnkey Podcast Productions. You're the expert. Your podcast will prove it.  

 

 

 

Daniel Blumberger

Date of appointment May 8, 2020

Date created May 3, 2020

 

Critically Speaking Guest Interview

 

https://app.acuityscheduling.com/schedule.php?owner=16987289&action=appt&id%5B%5D=29e531037007b14b2f367229a9f7cb65

 

Name: Daniel Blumberger

Phone: (415) 535-8501

Email: daniel.blumberger@camh.ca

 

Guest Intake Form

============

Provide a link to your website or online professional profile/bio: https://www.camh.ca/en/science-and-research/science-and-research-staff-directory/danielblumberger

 

Provide any links to social media or publications such as articles or books you would like to share with the audience.: 

 

Please provide your professional affiliation and areas of expertise and you would like it to appear in our show notes.: Medical Head and Co-Director, Temerty Centre for Therapeutic Brain Intervention at the Centre for Addiction and Mental Health

Associate Professor in the Department of Psychiatry at the University of Toronto

 

Is there anything specific you’d like to share with our audience?: no

 

Are there specific questions you'd like Therese Markow to ask you? Please include them here.: 

 

By selecting yes, you grant permission to Therese Markow to record the interview, post content on the internet obtained during the interview, and promote the content. Once published, any editing will not be possible.: yes