Critically Speaking
The opinions expressed by Dr. Beyrer are his own and not those of his employer. In this episode, Therese Markow and Dr. Chris Beyrer discuss the importance of USAID, highlighting its role in global health and development, particularly through programs like PEPFAR, which has saved 25 million lives and prevented millions of HIV infections. Dr. Beyrer emphasizes that the economic and security benefits of USAID, whose support amounts to less than 1% of the total US federal budget, have had important benefits at home in the United States. It protects us from infectious diseases like Ebola and...
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In this episode, Therese Markow and Dr. Adam Berinsky discuss political rumors and misinformation. Dr. Berinsky defines rumors as unsubstantiated claims without evidence, emphasizing their social transmission. He identifies two factors influencing rumor belief: conspiratorial thinking and partisan polarization. Berinsky's research reveals that while some people firmly believe rumors, others are ambivalent and more open to correction. He suggests focusing on these undecided individuals rather than entrenched believers. Berinsky also highlights the role of political leaders in spreading...
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In this episode, Therese Markow and Dr. James Alcock discuss what near-death experiences are and the increase in them in recent years due to improvements in medical technology. While near-death experiences (NDEs) have been known about for a long time, we, as a scientific community, are starting to understand more about what they mean for neurological processes. However, despite knowing the science of what is happening, NDEs and how they are experienced are subject to one’s own beliefs, context, and even religious framework. Dr. Alcock and Therese also discuss the relationship between...
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In this episode, Therese Markow and Dr. Deborah Lang discuss the rise of skin cancer, particularly melanoma, and its causes. Dr. Lang explains that skin cancers are derived from different skin cells: basal cell carcinoma and squamous cell carcinoma, both linked to UV exposure, and melanoma, which can be UV-independent and linked to genetic susceptibility. Dr. Lang emphasizes the importance of early detection and personalized medicine, noting that melanoma can metastasize early. She also highlights the role of genetic mutations in cancer development and the impact of funding cuts on cancer...
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In this episode, Therese Markow and Dr. Anice Lowen discuss the bird flu outbreak, highlighting the virus’s spread from birds to dairy cattle and recorded cases of human infection. Dr. Lowen explains the differences between influenza A and influenza B viruses, talks about which type causes pandemics, and what we can do to try to prevent future pandemics from these flu strains. Key Takeaways: An epidemic affects a specific region, a pandemic is global. Only Influenza A viruses can cause pandemics and are often transmitted via birds and mammals. Humans can become...
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In this episode, Therese Markow and Dr. Joshua Weitz discuss his book "Asymptomatic: The Silent Spread of COVID-19 and the Future of Pandemics" and his work in understanding the risk of COVID spread from as early as spring of 2020. He highlights the double-edged sword of asymptomatic infections, discusses what governments could do to help mitigate at-risk populations, and what we, as individuals, can do to help keep everyone safe. Dr. Weitz criticizes early predictions of COVID-19's disappearance by mid-2020, attributing the error to underestimated infections and behavioral changes. He...
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When we hear the term tumor or cancer, the image that often comes to mind is a bunch of bad cells next to normal ones, and growing. Like many things, it's just not that simple. How do the normal cells turn bad? Can our immune systems detect the cancer cell and kill it? Why does some initially successful chemotherapy stop working? Why does cancer spread? These are all great questions, since cancers of one kind or another will affect so many of us either as patients, friends, or loved ones. Well, basic science is providing some critical answers. In today’s episode, Therese Markow and Dr. Ajit...
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In this episode, Therese Markow and Dr. Jodi Gilman discuss the implications of cannabis use on health and safety. Dr. Gilman explains that THC, the main psychoactive compound in cannabis, binds to cannabinoid receptors in the brain, affecting areas involved in emotion, memory, and decision-making. Cannabis use can lead to long-term brain alterations, particularly in adolescents, frequent users, and those using high-potency products. Dr. Gilman highlights the risks of cannabis-induced psychosis, depression, and anxiety, especially in those with a family history of psychosis. She also notes the...
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In this episode, Therese Markow and Dr. Robert Meade, an expert in thermal physiology, discuss the dangers posed to human health by the rising heat. Dr Meade explains that extreme heat is a combination of air temperature and humidity, which can strain the body's ability to regulate temperature. He notes that older adults and women may be more vulnerable to heat stress due to reduced sweating and cardiovascular function. They talk about the differences between heat stress and heat stroke and how to identify symptoms to keep an eye on if you are in a hot environment. The discussion highlights...
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In this episode, Therese Markow and Dr. Brandon Sparks discuss the phenomenon of involuntary celibacy (incels). Dr. Sparks, an applied forensic psychologist, explains that incels are men experiencing long-term involuntary celibacy, often due to social exclusion and bullying during adolescence. Incels, primarily aged 18-30, are less likely to be in education or employment. The term "incel" originated from a woman's project at Carleton University. Incels often self-identify online, where they discuss the "Black Pill" philosophy, a nihilistic view of society. Dr. Sparks highlights the need for...
info_outlineIn this episode, Therese Markow and Dr. Joel Gallant discuss the history and evolution of HIV treatment and prevention. He highlights the changes of treatment from early AZT, to the extensive multi-drug regimens of the 90s, and the current single-pill treatment with minimal side effects. They also discuss the racial and regional disparities of new HIV cases in the US. Despite progress, challenges persist, including stigma, lack of healthcare access, and resistance to treatments. Dr. Gallant also gives more information on hope for ending the epidemic and hope for a cure.
Key Takeaways:
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With early diagnosis and treatment of HIV, AIDS is not commonly seen anymore, though it still exists.
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“HIV is a retrovirus, meaning that it has enzymes that allow it to transcribe RNA into DNA, the reverse of the usual process in which DNA is transcribed into RNA. The viral DNA can then be inserted into the DNA of human cells.
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With more research, we’ve seen a steady improvement with more, safer drug choices, and better and easier combinations. Most people can be treated with a single pill once a day and are expected to live a normal lifespan in good health.
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In the US, no one has to go without treatment based on inability to pay. Even people who are uninsured and live in states that didn't expand Medicaid can get comprehensive HIV care, including medications, through clinics established by the Federal Ryan White Care Program.
"We do know that treatment is highly effective at preventing transmission, including sexual and mother-to-child transmission. It’s so effective that the CDC says that if your viral load (how we measure how much virus there is in your blood) is fully suppressed on treatment (having an undetectable virus) then you cannot transmit HIV. Treatment is 100% effective as prevention." — Dr. Joel Gallant
Episode References:
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Ryan White HIV/AIDS Program: https://ryanwhite.hrsa.gov/
Connect with Dr. Joel Gallant:
Professional Bio: https://www.iasusa.org/faculty/joel-e-gallant-md-mph/
Website: https://www.axcesresearch.com/
LinkedIn: https://www.linkedin.com/in/joel-gallant-b6875432/
Connect with Therese:
Website: www.criticallyspeaking.net
Threads: @critically_speaking
Email: [email protected]
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