Critically Speaking
Have you or someone you loved considered taking antidepressants for mental health, but had concerns? Listen in as Dr. Andrew Novick talks about the research and the science behind these drugs and other options for those struggling with MDD and other mental health concerns. In this episode, Therese Markow and Dr. Andrew Novick discuss major depressive disorder (MDD) and its treatment options. Dr. Novick explains the key characteristics of MDD and discusses some of the many treatment options, which include psychotherapy, particularly cognitive-behavioral therapy, and pharmacological...
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From testosterone craze headlines to myths about prostate cancer, fertility, and aggression, men are getting a lot of confusing messages about their sexual health. Today, urologist and men’s health expert Dr. Justin Dubin cuts through the noise with science-backed answers to the questions men are often too embarrassed to ask. In this episode, Therese Markow and Dr. Justin Dubin discuss listener questions regarding men’s sexual health. Dr. Dubin explains the nuances of testosterone levels, noting that normal ranges vary and can impact overall health. He highlights the importance of...
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Do you ever feel exhausted by home life, even when the chores look “even”? This episode uncovers the hidden mental load running beneath every household and reveals how it quietly shapes stress, careers, and relationships. Today, Therese Markow and Dr. Allison Daminger discuss her research on cognitive labor, which reveals gender inequality in household decision-making. Allison interviewed 92 couples, and they discuss the results found between both queer and heterosexual couples throughout the study. These decisions were categorized into 10 domains, ranging from maintenance to...
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In this episode, Therese Markow and psychologist Dr. Elizabeth Scott discuss narcissism, its clinical definition, and the characteristics of “malignant narcissism”. Dr. Scott explains that narcissism involves patterns of grandiosity, a need for constant admiration, a lack of empathy, high levels of manipulation, and the narcissist’s “kryptonite” - criticism. They view themselves as the victim, never at fault. Despite their arrogance, they are very insecure. Dr. Scott also discusses why treatment is challenging and why therapy often focuses on managing symptoms rather than the deeper...
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What if the biggest risk factor for cancer, heart disease, and dementia isn’t your genes, diet, or blood pressure but aging itself? Listen in as biogerontologist Dr. Matt Kaeberlein reveals how understanding the biology of aging could add not just years to our lives, but healthy decades, and why your dog might hold some of the most important clues. In this episode, Therese Markow and Dr. Matt Kaeberlein discuss aging research. He explains that aging is characterized by damage accumulation and loss of resilience, leading to functional decline. Matt highlights the hallmarks of aging,...
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Hidden in your water, food, and even your blood, forever chemicals (PFAS) are nearly impossible to destroy - and now U.S. regulations are being rolled back. Listen in to how PFAS became unavoidable, what they’re doing to our health, and whether we can ever truly get rid of them. In this episode, Therese Markow and Dr. Carrie McDonough discuss perfluoroalkyl substances (PFAS), also known as forever chemicals. PFAS, which include PFOA and PFOS, are persistent organic pollutants used in various products, such as Teflon for your cooking pans and Scotchgard. While there are natural...
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Peptides are being sold online as miracle fixes for energy, healing, and longevity—but what if the science behind them is shaky, or even dangerous? In this episode, Therese Markow and Dr. Leigh Baxt pull back the curtain on the peptide craze, revealing what we really know (and don’t know) about these heavily marketed “biohacks.” They discuss the complexities and risks of unapproved peptides, which are often marketed for health enhancement. Dr. Baxt explains what peptides are and speaks to those drugs that are FDA-approved, like GLP-1 agonists and insulin, but also...
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Dr. Kate Mangino exposes the hidden burden of cognitive and emotional labor at home and explains how “benevolent sexism” and unequal household roles quietly push women to the breaking point. In this episode, Therese Markow and Dr. Kate Mangino discuss gender inequality in household responsibilities. Kate differentiates between structural and social inequalities, noting that societal norms perpetuate these “male” and “female” roles. She also emphasizes the importance of cognitive labor, which often falls on women, and addresses the emotional impact of household tasks on...
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Our cities are anything but concrete jungles. Listen in as Therese Markow and Dr. Dan Werb reveal the hidden world of synanthropes - the wild animals that not only live alongside us, but thrive because of us. In this episode, Therese Markow and Dr. Dan Werb discuss Dan’s new book “Our Wild Familiars”, which explores how animals (and plants) adapt to urban environments. They dive into the history and impact of synanthropes, such as raccoons, coyotes, and rats. He also highlights the adaptability of these animals and why they have expanded into cities. Dr. Werb emphasizes the importance of...
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In this episode, Therese Markow and Dr. Boris Konrad discuss the striking impact of memorization on functional changes and connectivity in the brain. Dr. Konrad is a neuroscientist as well as an international Memory Champion. He not only studies brain connectivity, but also trains other memory athletes, as well as those who simply wish to improve their memories. They discuss more specific aspects of memorization and its benefits across a range of other activities and problem-solving, independent of the particular memorization training utilized. Dr. Konrad summarizes his recent study, published...
info_outlineIn this episode, Therese Markow and Dr. Daniel Buchman discuss chronic pain, affecting over 20% of the population in the US, Canada, and Europe. Chronic pain (persisting pain lasting over three months) includes conditions like arthritis, lower back pain, fibromyalgia, and phantom limb pain, among many others. Daniel highlights the challenges in pain assessment, the role of AI in pain management, and the ethical considerations, including bias in pain reporting. He notes that chronic pain increases suicide risk, and the conversation also touches on the stigma surrounding pain and opioid use.
Key Takeaways:
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Pain can come from an identifiable condition, but sometimes doesn't have a clear cause.
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Primary pain is the type of pain that is not explained by another disease. Secondary pain is pain that arises because of or is related to an underlying condition - perhaps injury, illness, disease, or other reason.
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When we talk about bias in health care providers, we also need to look at the broader societal bias that plays into those biases.
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As AI is used more in medicine, we do need to be aware of bias in the data sets that the AI is utilizing to learn and then use to make predictions.
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Pain is a warning sign. It is not, in and of itself, bad. It is telling you that something might need to be addressed in your body.
"There isn't a blood test or a brain scan or anything that can determine how much pain somebody's in, or what it's like to experience that pain. This is subjective because it depends on the person, and it depends on a whole host of factors, not just their biology. It depends on their psychology, social factors, cultural factors, and gender is a big part of this as well." — Dr. Daniel Buchman
Episode References:
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Buchman, Daniel Z.a,b,c,d. 2025 AI and the ethics of techno-solutionism in pain management. PAIN 166: 469-470. | DOI: 10.1097/j.pain.0000000000003389
Connect with Dr. Daniel Buchman:
Professional Bio: https://www.camh.ca/en/science-and-research/science-and-research-staff-directory/danielbuchman
Bluesky: https://bsky.app/profile/danielbuchman.bsky.social
X: https://x.com/DanielZBuchman
Google Scholar: https://scholar.google.ca/citations?user=3Yja_7QAAAAJ&hl=en
Connect with Therese:
Website: www.criticallyspeaking.net
Bluesky: @CriticallySpeaking.bsky.social
Instagram: @criticallyspeakingpodcast
Email: theresemarkow@criticallyspeaking.net
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