Critically Speaking
Ru Marshall pulls back the curtain on the man behind the myth of Carlos Castaneda, exposing the real lives, lies, and losses buried beneath his legendary books. In this episode, Therese Markow and Ru Marshall discuss the life and legacy of Carlos Castaneda, who claimed to have been trained as a shaman by Don Juan. Castaneda's books, which sold over 8 million copies, were initially believed but later dismissed as fiction. Marshall’s book, "American Trickster," explores Castaneda's origins in Peru and his life in the U.S. Castaneda, born Cesar Arana, was a charismatic storyteller who seduced...
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In this episode, Therese Markow and Patrick Wyman discuss Patrick’s latest book, Lost Worlds: How Humans Tried, Failed, Succeeded, and Built Our World. Patrick also discusses his journey as a historian from studying the Fall of Rome to popular history. He emphasizes the importance of understanding past climactic changes and their impact on human societies, including the development of agriculture and the rise of social hierarchies. Patrick also highlights the significance of migration and the diverse burial practices that reveal aspects of ancient societies’ beliefs and social...
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When a globally respected infectious disease expert is abruptly sidelined by an anti‑vaccine administration, what does it reveal about the future of public health and scientific integrity? In this episode, Therese Markow and Dr. Jeanne Marrazzo discuss her termination and whistleblower lawsuit against the U.S. government. She highlighted NIAID's critical role in infectious disease research, funding $6.6 billion annually. Dr. Marrazzo criticized the new administration's anti-vaccine stance, cessation of global HIV/AIDS funding, and termination of clinical trials, which she argued...
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In this episode, Therese Markow and Dr. Chelsea Polis discuss the evolution of reproductive rights in the U.S., highlighting the 2022 Supreme Court decision revoking the right to abortion and the historical context of contraception access. Dr. Polis also explains fertility awareness-based methods (FABMs) and their effectiveness, noting that some methods have moderate quality studies suggesting high effectiveness, while others are less reliable. She emphasizes the importance of evidence-based information, the need for stronger regulation of femtech products, and the potential privacy risks...
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In this episode, Therese Markow and Dr. Keith McCormick discuss what you need to know about osteoporosis and bone health. Dr. McCormick explains what causes osteoporosis, the importance of early bone density tests, and breaks down some of the lifestyle factors that affect bone health. They discuss the need for personalized treatment beyond only medication, and Dr. McCormick advocates for patient empowerment and comprehensive understanding to improve treatment outcomes. Key Takeaways: 50% of women will get osteoporosis. 20% of men will get osteoporosis. People...
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In this episode, Therese Markow and Dr. Dawn Sarno, a leading expert on cyber scams, discuss the prevalence and detection of phishing scams. Dawn explains that phishing often targets older adults due to their perceived lack of tech savvy and higher financial stakes, but notes that younger adults are also vulnerable, often due to impulsivity and poor online habits. She highlights the rise of AI-generated deep fakes, which make scams more convincing and harder to detect. Dawn advises slowing down and verifying suspicious communications, emphasizing the importance of cyber hygiene practices, such...
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In this episode, Therese Markow and Dr. Daniel Buchman discuss chronic pain, affecting over 20% of the population in the US, Canada, and Europe. Chronic pain (persisting pain lasting over three months) includes conditions like arthritis, lower back pain, fibromyalgia, and phantom limb pain, among many others. Daniel highlights the challenges in pain assessment, the role of AI in pain management, and the ethical considerations, including bias in pain reporting. He notes that chronic pain increases suicide risk, and the conversation also touches on the stigma surrounding pain and opioid use....
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In this episode, Therese Markow and Dr. David Hill discuss the rise of peanut allergies in children. David explains that anaphylaxis, a severe allergic reaction, is common in children, often triggered by food. He emphasizes the importance of early allergen introduction to prevent allergies. The LEAP study from 2015 showed that introducing peanuts before six months reduces the risk of peanut allergy. They also discuss other common allergies and the fact that many children outgrow milk and egg allergies by age four. Key Takeaways: The major allergens are milk, egg, soy,...
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In this episode, Therese Markow and Dr. Fred Miller discuss the autoimmune disease epidemic, highlighting the economic burden and the rise of diseases like juvenile diabetes, lupus, and multiple sclerosis. Dr. Miller explains that autoimmune diseases occur when the immune system attacks the body, affecting various organs. He notes that there are at least 150 types of autoimmune diseases, with prevalence rates varying from 0.1% to 5% of the population - the exact number is unknown due to the need for better registries to track these diseases. Dr. Miller also discusses the role of genetics and...
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In this episode, Therese Markow and Dr. John Kisiel discuss early cancer detection using liquid biopsies. Dr. Kisiel explains that liquid biopsies detect cancer signals in blood and urine, including tumor cells, fragments, proteins, and DNA. He highlights the FDA's approval of a blood test for colon cancer and the development of multi-cancer early detection tests. Dr. Kisiel notes that false positive and false negative rates vary by test. He emphasizes the potential of liquid biopsies to complement, not replace, standard screening methods and the need for further validation and clinical...
info_outlineWhen a globally respected infectious disease expert is abruptly sidelined by an anti‑vaccine administration, what does it reveal about the future of public health and scientific integrity?
In this episode, Therese Markow and Dr. Jeanne Marrazzo discuss her termination and whistleblower lawsuit against the U.S. government. She highlighted NIAID's critical role in infectious disease research, funding $6.6 billion annually. Dr. Marrazzo criticized the new administration's anti-vaccine stance, cessation of global HIV/AIDS funding, and termination of clinical trials, which she argued endangered public health. Dr. Marrazzo filed a whistleblower complaint in September 2025, leading to her firing in October. She now leads the Infectious Disease Society of America, advocating for evidence-based policies and scientific integrity.
Key Takeaways:
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Tuberculosis (TB, formerly known as Consumption) is now the top global killer as an infectious disease.
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Shutting down clinical trials and cutting international research funding mid‑stream doesn’t just waste taxpayer dollars; it endangers patients who rely on those therapies and violates core ethical standards.
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Political ideology overriding scientific evidence can rapidly dismantle decades of progress in vaccines, global health research, and public trust.
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Independent professional societies and medical organizations now play a critical role in evidence above ideology, preserving rigorous guidelines, publishing unbiased research, and speaking truth to power when government agencies are silenced or hollowed out.
"What I don't think people realize is the power of the platform that the Secretary and indeed the President have. The tragic part about this is that we've spent decades building up that trust, trying to make sure that it was justified, and to see that just summarily destroyed, there's no other word for it, is really, really tragic. I don't know what it's going to take to build it up again." — Jeanne Marrazzo, MD
Connect with Jeanne:
Professional Bio: https://www.niaid.nih.gov/about/jeanne-marrazzo-md-mph
Website: https://www.idsociety.org/
LinkedIn: https://www.linkedin.com/in/jeanne-marrazzo-203463179
Connect with Therese:
Website: www.criticallyspeaking.net
Bluesky: @CriticallySpeaking.bsky.social
Instagram: @criticallyspeakingpodcast
Email: theresemarkow@criticallyspeaking.net
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