Dr. Alice Marwick: The Manosphere, Feminism, Misandry, Misogyny
Critically Speaking
What starts as advice on fitness, dating, or success can lead young men into a world of grievance and reshape how they see women, masculinity, and themselves. Dr. Alice Marwick unpacks how the manosphere works, why it’s growing, and the real-world harm it can cause. In this episode, Therese Markow and Dr. Alice Marwick examine the manosphere’s origins, business models, influence on young men, and links to misogyny, harassment, and extremist movements. They discuss what the manosphere is, how it appears in different environments, and the social impact of these manosphere influencers....
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Dr. Jonathan Cherry: CTE - Repeated Head Injuries
Critically Speaking
CTE isn’t just an NFL story, and a diagnosed concussion isn’t the only warning sign. Dr. Jonathan Cherry explains how years of repetitive impacts may quietly change the brain, and why researchers are racing to find a way to detect it during life. In this episode, Therese Markow and Dr. Jonathan Cherry discuss his research into understanding how repetitive head injuries cause progressive brain changes and their work to learn how to detect the disease during life. They break down the difference between CTE and concussions, explain who is more likely to get CTE, and explain the links...
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Dr. Cheryl Rosenfeld: Placentas - How They Affect Later Adult Health
Critically Speaking
Things you do or are exposed to early in life, including during fetal development, can actually affect your health later in adulthood. Normally, we're unaware of it, and it's difficult to make the connection. Today, Dr. Cheryl Rosenfeld dives into some of the research regarding placentas and their key implications in every life. In this episode, Therese Markow and Dr. Cheryl Rosenfeld discuss how prenatal exposures can alter placental function, fetal brain development, and later-life health, with varying effects based on fetal sex. They expose the dangers of BPA and substitutes such as BPS,...
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Dr. Jennifer Nuzzo: The Next Pandemic - Are We Prepared?
Critically Speaking
The U.S. declared measles eliminated in 2000 — so why are we seeing more cases and deaths than in the last 30 years? Dr. Jennifer Nuzzo reveals the hyper-local vaccination gaps driving the resurgence, and why preparing for the next pandemic starts on your block, not in Washington. In this episode, Therese Markow and Dr. Jennifer Nuzzo discuss the recurring nature of pandemics that require prevention, preparedness, and coordinated action from global, national, and local organizations, institutions, and communities. They discuss the current preparedness systems, where they are working, and...
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Daniel Aaron, M.D., J.D.: Lack of FDA Food Safety Oversight
Critically Speaking
In this episode, Therese Markow and Dr. Daniel Aaron discuss the inadequate oversight of food additives by the FDA, particularly the agency's GRAS or “Generally Recognized as Safe” process, which allows unsafe additives to reach the market without proper scrutiny. Dr. Aaron highlights industry conflicts of interest, the lack of reporting requirements, the need for stricter regulation to protect public health, and discusses what is needed for the FDA to be better able to make impactful changes. Key Takeaways: The majority of food additives in the US are not vetted by...
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Dr. Paul Schulz: Hot News About Preventing Alzheimer's
Critically Speaking
Have you ever wondered what the purpose of staying up to date on your vaccines is? Well, new research is showing that not only does it help to prevent the disease the vaccine is protecting you from, but it may also reduce your risk of Alzheimer’s and other dementia related diseases. In this episode, Therese Markow and Dr. Paul Schulz discuss the exciting discovery that influenza vaccines may reduce the risk of Alzheimer’s by up to 40%. Dr. Schulz’s research suggests that high-dose vaccines (offered to those over the age of 65) are more effective, particularly in women....
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Dr. Zaldy Tan: What if it's Dementia?
Critically Speaking
Worried about what your forgetfulness really means and whether it’s just aging or the start of something more serious? Listen in as memory expert Dr. Zaldy Tan breaks down the different types of dementia, how early detection really works, and what you can do now to protect your brain and plan for the future. In this episode, Therese Markow and Dr. Zaldy Tan discuss his new book, “What to Remember When You Are Forgetting,” which addresses cognitive decline and dementia. Dr. Tan discusses the main types of dementia, the importance of early diagnosis, and how dementia varies from...
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Dr. Darren Linvill: Detecting Rampant Disinformation
Critically Speaking
Have you ever wondered how trolls, bots, and paid influencers are quietly manipulating what you see online and why even smart, skeptical people fall for it? Today, disinformation expert Dr. Darren Linvill pulls back the curtain on the tactics that bad actors are using to try and shape our beliefs. In this episode, Therese Markow and Dr. Darren Linvill discuss the various forms of digital deception and the strategies used by state actors to manipulate global discourse. Dr. Linvill distinguishes between misinformation, disinformation, and malinformation and gives examples of each,...
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Timothy Caulfield: The Certainty Illusion
Critically Speaking
Drowning in wellness hype, viral “experts,” and five-star opinions that feel more real than facts? In this episode, law and public health scholar Timothy Caulfield exposes the certainty illusion — how “scienceploitation”, predatory journals, and weaponized opinions quietly shape what we believe about our health. Today, Therese Markow and Timothy Caulfield discuss Tim’s latest book, break down the misinformation drivers that are contributing to the delegitimization of scientific expertise, and the three illusions that are being used to distort public perception. From...
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Dr. Aly Cohen: Killers in the Environment
Critically Speaking
The last few decades have seen a continuing rise in really serious and often fatal health problems. The list is long: cancer, heart disease, diabetes, infertility, autoimmune diseases, and autism, just to name a few. While vulnerability to disease often has an underlying genetic predisposition, there have to be environmental triggers to set these diseases in motion. In this episode, Therese Markow and Dr. Aly Cohen discuss just these topics and what we can look for on a daily basis, as well as the small changes that we can, individually, do to make our lives a little healthier. ...
info_outlineWhat if the biggest risk factor for cancer, heart disease, and dementia isn’t your genes, diet, or blood pressure but aging itself? Listen in as biogerontologist Dr. Matt Kaeberlein reveals how understanding the biology of aging could add not just years to our lives, but healthy decades, and why your dog might hold some of the most important clues.
In this episode, Therese Markow and Dr. Matt Kaeberlein discuss aging research. He explains that aging is characterized by damage accumulation and loss of resilience, leading to functional decline. Matt highlights the hallmarks of aging, such as deregulation of nutrient sensing and DNA damage, and the potential of interventions like rapamycin to slow aging. He notes that biological age is a significant risk factor for major diseases, and that understanding and addressing aging biology could significantly extend human lifespan. They also discuss the Dog Aging Project, with 55,000 participating dogs, which aims to uncover genetic and environmental factors influencing health and longevity in pets.
Key Takeaways:
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Our bodies are constantly being exposed to stress, and stress can move us out of the optimal zone of function. When we're young, we're very resilient and able to come back to optimal function. As we get older, we lose that resilience.
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When we slow aging in laboratory animals, we prevent the onset and progression of all of the major age-related functional declines and diseases simultaneously, because we've slowed biological aging. Based on what’s possible in mice, it is estimated that we could potentially gain 2-3 additional decades of life if we can achieve this in humans.
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There is a genetic component to longevity; however, how big that genetic component is to longevity is hotly debated. The environment is also a large contributor.
"Biological age is the single greatest risk factor for nine of the top 10 killers in the United States, and it's not a small effect. The magnitude of effect from biological aging dwarfs all of the other risk factors combined…it’s useful to appreciate how important biological age is to the risk of developing many of the chronic diseases and functional declines that limit quality and quantity of life for most people." — Dr. Matt Kaeberlein
Episode References:
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Dog Aging Project: https://dogagingproject.org/
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Dog Aging Institute: https://dogaginginstitute.org/
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Longevity for Dogs: https://www.youtube.com/@LongevityForDogs
Connect with Dr. Matt Kaeberlein:
Professional Bio: https://halo.dlmp.uw.edu/people/matt-kaeberlein/
Publications: https://pubmed.ncbi.nlm.nih.gov/?term=%22kaeberlein+m%22[author]
YouTube: https://www.youtube.com/@mkaeberlein
LinkedIn: https://www.linkedin.com/in/mkaeberlein/
Connect with Therese:
Website: www.criticallyspeaking.net
Bluesky: @CriticallySpeaking.bsky.social
Instagram: @criticallyspeakingpodcast
Email: theresemarkow@criticallyspeaking.net
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