Critically Speaking
What starts as advice on fitness, dating, or success can lead young men into a world of grievance and reshape how they see women, masculinity, and themselves. Dr. Alice Marwick unpacks how the manosphere works, why it’s growing, and the real-world harm it can cause. In this episode, Therese Markow and Dr. Alice Marwick examine the manosphere’s origins, business models, influence on young men, and links to misogyny, harassment, and extremist movements. They discuss what the manosphere is, how it appears in different environments, and the social impact of these manosphere influencers....
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CTE isn’t just an NFL story, and a diagnosed concussion isn’t the only warning sign. Dr. Jonathan Cherry explains how years of repetitive impacts may quietly change the brain, and why researchers are racing to find a way to detect it during life. In this episode, Therese Markow and Dr. Jonathan Cherry discuss his research into understanding how repetitive head injuries cause progressive brain changes and their work to learn how to detect the disease during life. They break down the difference between CTE and concussions, explain who is more likely to get CTE, and explain the links...
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Things you do or are exposed to early in life, including during fetal development, can actually affect your health later in adulthood. Normally, we're unaware of it, and it's difficult to make the connection. Today, Dr. Cheryl Rosenfeld dives into some of the research regarding placentas and their key implications in every life. In this episode, Therese Markow and Dr. Cheryl Rosenfeld discuss how prenatal exposures can alter placental function, fetal brain development, and later-life health, with varying effects based on fetal sex. They expose the dangers of BPA and substitutes such as BPS,...
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The U.S. declared measles eliminated in 2000 — so why are we seeing more cases and deaths than in the last 30 years? Dr. Jennifer Nuzzo reveals the hyper-local vaccination gaps driving the resurgence, and why preparing for the next pandemic starts on your block, not in Washington. In this episode, Therese Markow and Dr. Jennifer Nuzzo discuss the recurring nature of pandemics that require prevention, preparedness, and coordinated action from global, national, and local organizations, institutions, and communities. They discuss the current preparedness systems, where they are working, and...
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In this episode, Therese Markow and Dr. Daniel Aaron discuss the inadequate oversight of food additives by the FDA, particularly the agency's GRAS or “Generally Recognized as Safe” process, which allows unsafe additives to reach the market without proper scrutiny. Dr. Aaron highlights industry conflicts of interest, the lack of reporting requirements, the need for stricter regulation to protect public health, and discusses what is needed for the FDA to be better able to make impactful changes. Key Takeaways: The majority of food additives in the US are not vetted by...
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Have you ever wondered what the purpose of staying up to date on your vaccines is? Well, new research is showing that not only does it help to prevent the disease the vaccine is protecting you from, but it may also reduce your risk of Alzheimer’s and other dementia related diseases. In this episode, Therese Markow and Dr. Paul Schulz discuss the exciting discovery that influenza vaccines may reduce the risk of Alzheimer’s by up to 40%. Dr. Schulz’s research suggests that high-dose vaccines (offered to those over the age of 65) are more effective, particularly in women....
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Worried about what your forgetfulness really means and whether it’s just aging or the start of something more serious? Listen in as memory expert Dr. Zaldy Tan breaks down the different types of dementia, how early detection really works, and what you can do now to protect your brain and plan for the future. In this episode, Therese Markow and Dr. Zaldy Tan discuss his new book, “What to Remember When You Are Forgetting,” which addresses cognitive decline and dementia. Dr. Tan discusses the main types of dementia, the importance of early diagnosis, and how dementia varies from...
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Have you ever wondered how trolls, bots, and paid influencers are quietly manipulating what you see online and why even smart, skeptical people fall for it? Today, disinformation expert Dr. Darren Linvill pulls back the curtain on the tactics that bad actors are using to try and shape our beliefs. In this episode, Therese Markow and Dr. Darren Linvill discuss the various forms of digital deception and the strategies used by state actors to manipulate global discourse. Dr. Linvill distinguishes between misinformation, disinformation, and malinformation and gives examples of each,...
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Drowning in wellness hype, viral “experts,” and five-star opinions that feel more real than facts? In this episode, law and public health scholar Timothy Caulfield exposes the certainty illusion — how “scienceploitation”, predatory journals, and weaponized opinions quietly shape what we believe about our health. Today, Therese Markow and Timothy Caulfield discuss Tim’s latest book, break down the misinformation drivers that are contributing to the delegitimization of scientific expertise, and the three illusions that are being used to distort public perception. From...
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The last few decades have seen a continuing rise in really serious and often fatal health problems. The list is long: cancer, heart disease, diabetes, infertility, autoimmune diseases, and autism, just to name a few. While vulnerability to disease often has an underlying genetic predisposition, there have to be environmental triggers to set these diseases in motion. In this episode, Therese Markow and Dr. Aly Cohen discuss just these topics and what we can look for on a daily basis, as well as the small changes that we can, individually, do to make our lives a little healthier. ...
info_outlineHave you or someone you loved considered taking antidepressants for mental health, but had concerns? Listen in as Dr. Andrew Novick talks about the research and the science behind these drugs and other options for those struggling with MDD and other mental health concerns.
In this episode, Therese Markow and Dr. Andrew Novick discuss major depressive disorder (MDD) and its treatment options. Dr. Novick explains the key characteristics of MDD and discusses some of the many treatment options, which include psychotherapy, particularly cognitive-behavioral therapy, and pharmacological interventions like SSRIs. He highlights the effectiveness of esketamine for treatment-resistant MDD, and also addresses the controversy surrounding SSRIs and the potential of new treatments like psilocybin, noting ongoing research and regulatory challenges.
Key Takeaways:
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Major Depressive Disorder (MDD) can begin in childhood, but can often show up as irritability rather than other traditional depressive symptoms that we would see in adults. It’s also more common to see it manifest during puberty, rather than before.
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Treating MDD does not require starting with psychotherapy. Medication can help more immediately, especially because there is an obstacle to accessible therapy for a lot of people. It can also be a tool used in tandem with therapy.
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While there are no blood tests or simple diagnostic tests to see if you have depression, like with an infectious disease model, there are some brain scans that can show signs of depression, especially across wide populations of individuals.
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There is no one gene that is associated with MDD. However, through research, many different genes have been identified, often related to brain function and stress response.
"If depression goes untreated, the most awful consequence of that is potential suicide." — Dr. Andrew Novick
Connect with Dr. Andrew Novick:
Professional Bio: https://som.cuanschutz.edu/Profiles/Faculty/Profile/29109
ResearchGate: https://www.researchgate.net/profile/Andrew-Novick
LinkedIn: linkedin.com/in/annovick
Connect with Therese:
Website: www.criticallyspeaking.net
Bluesky: @CriticallySpeaking.bsky.social
Instagram: @criticallyspeakingpodcast
Email: theresemarkow@criticallyspeaking.net
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