Understanding the Significance of Research in the Treatment of Kidney Diseases
Release Date: 01/24/2023
Polycystic Kidney Disease (PKD) Centers of Excellence
Let’s Talk About Kidneys
Polycystic kidney disease (PKD) is a genetic disorder that can lead to chronic kidney disease, hypertension, and kidney failure. Affecting between 500,000 and 600,000 Americans, treatment targets symptom management with diet, medications, and, if needed, dialysis or a kidney transplant.
info_outline
What is Polycystic Kidney Disease (PKD)?
Let’s Talk About Kidneys
Polycystic Kidney Disease (PKD) affects about 600,000 people in the United States, according to the PKD Foundation. It is one of the most common genetic kidney disorders, yet many people don’t even know they have it until later in life. Today, we’ll break down what PKD is, how it’s diagnosed, and how people can live well with it.
info_outline
Kidney Stones
Let’s Talk About Kidneys
In this episode of Let’s Talk About Kidneys, Dr. Jayasree Grandhi of Dallas Nephrology Associates breaks down kidney stones—what they are, what causes them, and how to prevent and treat them. Affecting up to 1 in 5 men and 1 in 10 women, kidney stones are common but manageable with the right care.
info_outline
Pregnancy and Kidney Disease: What to expect?
Let’s Talk About Kidneys
Chronic Kidney Disease (CKD) is a condition that affects how the kidneys work over time. For women with CKD who are planning to have a family, there are important factors to consider to ensure the best possible outcomes. Can I have a baby if I have CKD?
info_outline
Kidney Disease: From Diagnosis, Staging and Common Lab Tests
Let’s Talk About Kidneys
In this episode of Let's Talk About Kidneys, Dr. Lauren McDonald, a nephrologist with Dallas Nephrology Associates, discusses the diagnosis, staging, and common tests for patients with chronic kidney disease (CKD). Dr. McDonald explains how kidney disease is diagnosed, common symptoms, and some of the key tests, including BUN, creatinine, GFR, hemoglobin A1C, kidney biopsies, and more. She also discusses the importance of being your own healthcare advocate, family histories, how to maintain health records, and the importance of monitoring your diabetes, and...
info_outline
What is New in Kidney Transplant?
Let’s Talk About Kidneys
This episode of Let's Talk About Kidneys, Dr. Saim, a nephrologist with Dallas Nephrology Associates, discusses what is new in kidney transplant. The podcast discusses advancements in kidney transplantation, focusing on the benefits and risks of living and deceased donor transplant. Dr. Saim highlights that over 25,000 transplants were performed last year, with nearly 7,000 from living donors. Living donor transplants offer better survival rates and shorter waiting time. The waiting list has nearly 100,000 patients, with blood group O having the longest wait. ...
info_outline
Dialysis Patients and Their Diet
Let’s Talk About Kidneys
Let's Talk About Kidneys Dialysis Patients and Their Diet In this episode of Let’s Talk About Kidneys, Dr. Rao, a nephrologist at Dallas Nephrology Associates, discusses the importance of diet for all dialysis patients. She emphasizes the need for dietary modifications even before dialysis, focusing on reducing salt intake, managing potassium and phosphorus levels, and maintaining adequate protein consumption. Introduction Dr. Rao shares her background, mentioning that she joined Dallas Nephrology Associates fifteen years ago and sees patients mostly in Mesquite, Sunnyvale, and...
info_outline
New Treatment Therapies In Kidney Care
Let’s Talk About Kidneys
In this episode of the Let’s Talk About Kidneys podcast, Dr. Roberto Collazo addresses the development of new treatments for kidney disease that are essential for slowing disease progression, improving patient outcomes, and preventing kidney failure. Throughout his discussion, he will examine various therapeutic options currently available, as well as those expected in the future. What types of treatments have there been in the past for patients with Chronic Kidney Disease (CKD)? Dr. Collazo addressed the medications available during the 1990s and early 2000s. He also discussed newly...
info_outline
Weight Management Strategies with CKD
Let’s Talk About Kidneys
In this episode of the Let’s Talk About Kidneys podcast, Dallas Nephrology Associates Dietitian, Nadiya Lakhani, RDN, CSR, LD, FNKF, explains why weight management is important to the general population and how it affects the kidneys. How does weight affect the kidneys? When the body carries more weight than it can handle, it increases the demand on the kidneys to hyper filtrate. In other words, it forces your kidneys to work harder, which will eventually cause them to be overworked. On the flip side, unintentional weight loss increases the risk of that person having increased...
info_outline
Kidney Transplant - Getting Started
Let’s Talk About Kidneys
In this episode of the Let’s Talk About Kidneys podcast, Dr. Muhammad Qureshi talks about the benefits of a kidney transplant, why it’s a good choice after kidney failure, and what the process looks like before, during and after. Why should a CKD patient consider a kidney transplant? Dr. Qureshi talks about the fact that there are both mortality and morbidity benefits of a kidney transplant. In other words, not only do you live longer, but you live better. Who qualifies for a kidney transplant? Anyone who has a kidney function less than 20% or someone who has already...
info_outlineListen in to hear Dr. Mehta fill us in on how DNA is involved in chronic kidney disease research, including the types of kidney disease that are under investigation within DNA medication clinical trials, the team roles in clinical trials, and what to consider if you are interested in applying to a clinical trial as a patient with kidney disease.
What is a Clinical Trial?
A clinical trial is a process in which a drug or medical procedure is tested on an adult patient with a specific illness or condition. In this case, DNA has participated and conducted research with different clinical trials ranging in study time from several weeks to several years. DNA conducts clinical trials on different types and stages of kidney disease. DNA currently has over twenty clinical studies in progress.
Team Roles in a Clinical Trial
The principal investigator is responsible for the conduct of the trial. Components of a clinical trial include patient safety, wellbeing, the eligibility of the patient, and events that may happen to a patient during the trial. Team members will communicate several times daily about patients in a current clinical trial.
Clinical Trial Phases
There are four clinical trial phases, phases one through four. The first phase is testing on humans, and the fourth involves after-market trials. Some drugs in trials can be directed towards specific types of kidney disease, such as diabetic or high blood pressure kidney disease. In addition, there are rare genetic kidney diseases that have medications in our clinical trials.
Should You Consider Enrolling in a Clinical Trial?
As a patient, if you enroll in a trial with DNA, you will receive the standard of care treatment that includes monitoring the disease and treatment with medications. Then, if you are assigned to the treatment phase, you’ll be able to receive treatment inside the clinical trial.