Beyond the Delivery Room: Data, Doulas, and Patient-Centered OB-GYN
MD Newsline
In this episode of MD Newsline, Dr. Dillon Bannis, an OB-GYN practitioner based in the South Side of Chicago, shares his insights on the evolving challenges and innovations in obstetric and gynecological care. Dr. Bannis explores how listening, collaboration, and technology are reshaping the patient experience—from prenatal care and delivery practices to addressing health disparities and integrating AI into medicine.
With a strong emphasis on patient-centered communication, interdisciplinary col
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Infant Feeding, Early Habits & Childhood Obesity: What Parents Need to Know
MD Newsline
In this episode of MD Newsline, Dr. Wanda Averhart, a general pediatrician and obesity medicine specialist, explores the complex causes and lifelong impacts of childhood obesity, emphasizing how early feeding practices, maternal health, and social disparities shape children's long-term outcomes.
Dr. Averhart provides a comprehensive look at how environmental, cultural, and biological factors contribute to rising obesity rates among children—especially in underrepresented communities. She discuss
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The Future of Myeloma: Quadruplets, CAR-T & Beyond
MD Newsline
In this episode of MD Newsline, Dr. Shaina A. Rozell, a hematologist-oncologist at Affiliate Oncology in Chicago, Illinois, explores the rapidly advancing field of multiple myeloma treatment. She discusses how quadruplet therapies, MRD monitoring, and novel immunotherapies like bispecific antibodies and CAR-T are transforming outcomes for patients. Dr. Rozell also examines disparities in access to care, the growing role of community practices in clinical trials, and the balance between extending survival
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HPV Throat Cancer Misdiagnoses And How Technology Shapes ENT Health
MD Newsline
In this episode of MD Newsline, Dr. Tonia L. Farmer, a board-certified otolaryngologist and head & neck surgeon, discusses the gaps in ENT care, the growing impact of HPV-related cancers, and the importance of education and early detection in improving outcomes—particularly for underserved communities. Drawing from years of practice, Dr. Farmer explores how social, behavioral, and environmental factors shape ENT health and shares insights on emerging research and technologies revolutionizing the field.
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Personalized Approaches to Metabolic Liver Disease and MASH Management
MD Newsline
In this episode of MD Newsline, Dr. Christopher Kaisa, Assistant Professor of Medicine in the Section of Gastroenterology, Hepatology, and Nutrition at the University of Chicago Medicine, provides an in-depth discussion on Metabolic Dysfunction-Associated Steatohepatitis (MASH) and the evolving strategies for its management. He explains the latest non-invasive diagnostic tools, pharmacologic advancements, and the importance of multidisciplinary care in improving outcomes for patients with metabolic liver
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What's Next in Diabetes Care: New Treatments and Tech Insights
MD Newsline
In this episode of MD Newsline, Dr. Rachael Sood, a diabetes nurse practitioner and certified diabetes care and education specialist from New Orleans, Louisiana, shares her insights from the 85th American Diabetes Association Scientific Sessions. As the founder of The Diabetes Collective, Dr. Sood discusses the evolution of diabetology—a specialized field focused solely on the identification, treatment, and management of diabetes across all patient populations.
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High-Risk Multiple Myeloma & Personalized Treatment
MD Newsline
In this episode of MD Newsline, Dr. Martin Kaiser, Consultant Hematologist at the Royal Marsden Hospital and Professor of Hematology at the Institute of Cancer Research, London, discusses groundbreaking advances in the diagnosis and management of high-risk multiple myeloma. Drawing insights from the OptiMUM trial and related studies, Dr. Kaiser explores how genetic profiling, long-term treatment intensity, and personalized approaches are transforming patient outcomes. He also examines the challenges of t
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Clinical Trials vs Real World Practice in Leukemia Treatment
MD Newsline
In this episode of MD Newsline, Dr. Mark R. Litzow, Professor of Medicine at the Mayo Clinic in Rochester, Minnesota, discusses the groundbreaking findings from the ECOG-ACRIN E1910 trial and the evolving role of immunotherapy in acute lymphoblastic leukemia (ALL). He explores how real-world evidence complements clinical trials, the challenges of standardizing measurable residual disease (MRD) testing, and the future of personalized treatment strategies in hematologic malignancies.
Dr. Litzow shares deep
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A New Way to Treat Adrenal Insufficiency with an Insulin Pump
MD Newsline
In this episode of MD Newsline, Dr. Sassan Mirfakhraee, adult endocrinologist and associate professor at the University of Texas Southwestern Medical Center, shares groundbreaking insights into the management of adrenal insufficiency. At the Endocrine 2025 conference, Dr. Mirfakhraee presented his research on utilizing insulin pumps to deliver hydrocortisone—an innovative off-label approach that is showing promising results for patients who remain symptomatic on oral therapy.
He explains how thi
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Fighting Bone Metastasis in Breast Cancer
MD Newsline
In this episode of MD Newsline, we welcome Dr. Emily Zboril, a PhD candidate at Virginia Commonwealth University, to discuss her groundbreaking research on ER-positive breast cancer with bone metastasis. Emily sheds light on the unique challenges of treating this condition, the role of the bone microenvironment, and how novel therapies like lazophoxifene may change the landscape of care.
She explains how endocrine therapies currently used to block estrogen signaling often worsen bone fragility, leading t
info_outlineDr. Litzow shares deep insights into how immunotherapy has transformed survival outcomes, how clinicians can balance efficacy and neuropsychiatric side effects, and why cross-disciplinary collaboration is key to advancing oncology care.
Episode HighlightsReal-World Evidence and Clinical Practice Dr. Litzow explains the growing importance of real-world data in validating and refining clinical trial outcomes. While clinical trials have strict eligibility criteria, real-world settings introduce more patient diversity, offering valuable insights into treatment efficacy and tolerability across broader populations.
The ECOG-ACRIN E1910 Trial and Immunotherapy Advances Dr. Litzow details the E1910 trial, which compared standard chemotherapy with and without blinatumomab, an immunotherapy agent targeting CD19 and CD3. The study demonstrated a significant survival benefit—85% versus 68%— for patients receiving blinatumomab, establishing it as a new standard of care for MRD-negative ALL patients.
Integrating MRD and Genomic Profiling in Decision-Making He highlights how MRD testing and molecular risk profiling are shaping treatment pathways, enabling clinicians to better identify patients who can potentially avoid bone marrow transplantation through effective immunotherapy.
Adapting Pediatric Regimens for Adult Patients Dr. Litzow discusses the use of pediatric-inspired chemotherapy regimens in younger adults and the challenges in adapting these treatments for older or high-risk patients. He emphasizes careful monitoring for toxicities such as hepatic and neuropsychiatric effects.
Balancing Treatment Intensity and Quality of Life With immunotherapy showing strong efficacy, Dr. Litzow anticipates future strategies that reduce chemotherapy exposure, lower toxicity, and improve patient quality of life—especially for older adults or those with comorbidities.
Future Directions: AI, Cross-Specialty Collaboration, and Inflammation Research Dr. Litzow shares his optimism about artificial intelligence enhancing trial data analysis and calls for cross-disciplinary collaboration between cancer biologists and clinicians. He also emphasizes the emerging role of inflammation in cancer development, urging broader, non-linear approaches to understanding disease mechanisms.
Key TakeawayDr. Litzow underscores a new era in ALL treatment—where immunotherapy, real-world evidence, and molecular diagnostics intersect to personalize care, extend survival, and minimize toxicity. As clinical science evolves, the focus is shifting from intensifying chemotherapy to optimizing immune-based precision therapies that improve both outcomes and quality of life.
Resources
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