#Epi 123 - SWITCH Trial - Decompressive Craniectomy with Medical treatment Vs Best medical treatment for Deep intra-cerebral haemorrhage
eCritCare Podcast
In this episode, we discuss the recently published SWITCH trial which compared the efficacy of decompressive craniectomy with best medical treatment vs best medical treatment alone for deep intra-cerebral hemorrhage.
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#Epi 122 - Diaphragmatic Dysfunction in Critically Ill patients
eCritCare Podcast
In this episode, we discuss the etiology of diaphragmatic dysfunction, its management and strategies for prevention.
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# Epi 121 - AMIKINHAL Trial - Inhaled Amikacin to prevent Ventilator associated pneumonia
eCritCare Podcast
In this episode, we discuss the recently published RCT AMIKINHAL, which tested the efficacy of inhaled amikacin in preventing VAP in ICU patients who were ventilated for> 72 hours. Although, this trail demonstrated reduced incidence of VAP in intervention arm, it's premature to adopt these practices widely in intensive care.
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#Epi 120 - NICO Trial - Intubation in Acute Drug Overdose - Does GCS matter?
eCritCare Podcast
In this episode, we discuss recently published RCT in JAMA "NICO trial", which evaluated the role of GCS based intubation vs non-invasive airway management. It is important to understand the nuances before generalising the conclusion of this trial.
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#Epi 119 - The role of IV Thyroxine in Brain Dead Organ Donor
eCritCare Podcast
In this episode, we discuss the recently published RCT in NEJM, which challenged the current dogma regarding the role of IV thyroxine in potential organ donor patient population.
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#Epi 118 - ECLS Shock Trial - Extra-corporeal support in Cardiogenic shock post-MI
eCritCare Podcast
In this episode, we discuss the recently published RCT "ECLS-Shock" trial in NEJM. This trial tested the benefit of instituting early extra-corporeal support in cardiogenic shock and suggested more harm in intervention arm compared to control arm.
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#Epi 117 - ELAN Trial - Early Vs Late Anticoagulation in Ischaemic stroke post -AF
eCritCare Podcast
In this episode, we discuss recently published landmark RCT which compared the timing for initiation of oral anticoagulation in patients who presented with ischaemic stroke with rapid AF.
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#Epi 116 - Steroids in Community Acquired Pneumonia
eCritCare Podcast
In this episode, we discuss the controversy surrounding the usage of steroids in Community-acquired pneumonia. This controversy arose after the CAPE-COD trial was published recently in NEJM. We discuss the pros and cons of administering steroids as a blanket treatment. We recommend caution and suggest considering the external validity of this trial before changing your practices.
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#Epi 115 - ICU Journal Club - MERCY Trial
eCritCare Podcast
In this episode, we discuss recently published RCT "MERCY Trial" which evaluated the efficacy of continuous infusion vs intermittent dosing strategy of Meropenem.
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#Episode 114- ICU Journal Club - PATCH Trial
eCritCare Podcast
In this episode, we discuss the recently published RCT "PATCH Trial", which evaluated the efficacy of pre-hospital tranexamic acid in patients with severe trauma. This trial confirmed the results of CRASH-2 trial, which demonstrated 28-day mortality benefit with the use of tranexaic acid in trauma if administered in < 3 hours. However, it failed to demonstrate any significant benefit with favourable neurological output at 6 months. This highlights the importance of Post-ICU care which at this stage is not standardised and varies across the globe.
info_outlineIn this episode, we discuss the landmark trial published in JAMA, which evaluated the efficacy of eCPR over standard strategy. We believe although a well-conducted trial, it's still not enough evidence to decide one way or the other w.r.t performing eCPR in patients with out of hospital cardiac arrest.