Podcast 879: A Case of Pediatric Anaphylactic Shock
Release Date: 11/27/2023
Emergency Medical Minute
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Carepoint Journal Club is a quarterly series with discussions about a medical topic, brought to you by Carepoint's Emergency Physicians.
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info_outlineContributor: Dr. Taylor Lynch
Educational Pearls:
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Time of arrival until intubation was 26 minutes but nobody tried anterior neck access like a cricothyrotomy until his dad arrived
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Traditional ACLS protocol is not enough for anaphylactic respiratory arrest
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Circulating O2 from compressions alone is not enough to sustain the brain
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Patients need a definitive airway and endotracheal tube is the best method
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BVM ventilation is not enough to get patients the oxygen they need
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Time to anoxic brain injury during a respiratory arrest is 4 minutes
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Definition of anaphylactic shock:
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Acute laryngeal involvement with bronchospasms after known exposure to an allergen
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Do not need to have skin symptoms like the classic wheal and flare
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Must also have either hypotension (from vasodilation or end-organ hypoperfusion) or severe GI symptoms (crampy abdominal pain or repetitive vomiting)
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Treatment of anaphylactic shock:
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Push-dose IV epinephrine is better than IM epinephrine because IM epinephrine takes 4 minutes to circulate and get to the lungs
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Ketamine has broncho-dilating properties so it can be used as an induction agent for intubation
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Albuterol and ipratropium as continuous bronchodilators
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Magnesium and IV steroids
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AMAX4 acronym
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Adrenaline, Muscle relaxant, Airway, Xtra (bronchodilators, ventilation, vasopressors, and consideration of pneumothorax), 4 minutes to anoxic brain injury
References
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Commins SP. Outpatient Emergencies: Anaphylaxis. Med Clin North Am. 2017;101(3):521-536. doi:10.1016/j.mcna.2016.12.003
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Ring J, Beyer K, Biedermann T, Bircher A, Duda D FJ et al. Guideline for acute therapy and management of anaphylaxis. S2 guideline of DGAKI, AeDA, GPA, DAAU, BVKJ, ÖGAI, SGAI, DGAI, DGP, DGPM, AGATE and DAAB. Allergo J Int. 2014;23(23):96-112.
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McKenzie B. AMAX4: Every Second Counts. Accessed Sunday, November 26, 2023. https://www.amax4.org/
Summarized by Jorge Chalit, OMSII | Edited by Meg Joyce & Jorge Chalit, OMSII