Data-Driven Medication Management Intelligence Platform with Yoona Kim Arine
Release Date: 11/04/2024
Aligning Incentives and Leveraging Technology to Improve Clinical Trials for Sponsors and Participants with Meri Beckwith Lindus Health TRANSCRIPT
Empowered Patient Podcast
Meri Beckwith, Co-Founder of Lindus Health, aims to transform clinical trials by changing the CRO model to leverage technology to improve patient recruitment, retention, and the experience of the sponsors and trial participants. While the compensation model for contract research organizations is often not aligned with trial outcomes, Lindus ties compensation to hitting milestones and outcomes. They emphasize the need for more flexible trial design and a decentralized and hybrid approach to reduce participant burden and bring drugs to market sooner. Meri explains, "This comes back to...
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Aligning Incentives and Leveraging Technology to Improve Clinical Trials for Sponsors and Participants with Meri Beckwith Lindus Health
Empowered Patient Podcast
Meri Beckwith, Co-Founder of Lindus Health, aims to transform clinical trials by changing the CRO model to leverage technology to improve patient recruitment, retention, and the experience of the sponsors and trial participants. While the compensation model for contract research organizations is often not aligned with trial outcomes, Lindus ties compensation to hitting milestones and outcomes. They emphasize the need for more flexible trial design and a decentralized and hybrid approach to reduce participant burden and bring drugs to market sooner. Meri explains, "This comes back to...
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AI-Powered Cancer Biomarker Digital Detection Informs and Accelerates Decisions of Pathologists and Oncologists with Greg Hamilton io9 TRANSCRIPT
Empowered Patient Podcast
Greg explains, "For many of these cancers, determining the right cancer treatment is the difference between life and death. When we look at how we treat cancer today, what hasn’t changed is that there’ll be a biopsy. So, they take a piece of the tumor out and send that tumor to a pathologist. Pathologists will take that tumor and put it in a glass slide. They usually use what’s called H&E, they kind of stain it to read it better. But basically, a pathologist is looking under a microscope at the cells, and that’s how we diagnose cancer. That’s the formal way that we diagnose...
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AI-Powered Cancer Biomarker Digital Detection Informs and Accelerates Decisions of Pathologists and Oncologists with Greg Hamilton io9
Empowered Patient Podcast
Greg Hamilton, CEO of io9, aims to enable precision oncology treatments for patients globally. The company has developed an AI-powered biomarker analysis platform called OncoGaze that can rapidly analyze digital pathology images to identify cancer biomarkers. This enables pathologists to efficiently and quickly digitize and analyze tumor samples and oncologists to start patients on the appropriate targeted therapy much faster. Greg explains, "For many of these cancers, determining the right cancer treatment is the difference between life and death. When we look at how we treat...
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Leveraging Antibody Phage Display Library to Generate Unique Bispecific Antibodies for Solid Tumors with Dr. Jeng Her AP Biosciences TRANSCRIPT
Empowered Patient Podcast
Dr. Jeng Her, Founder and CEO of AP Biosciences, is developing T-Cube bispecific antibodies that can target cancer cells and engage T-cells to kill them more effectively and safely than existing treatments. The company is focused on treating hard-to-treat cancers such as HER2-positive breast cancer, lung cancer, head and neck cancer, and pancreatic cancer. The T-Cube bispecific antibodies use CD137 instead of CD3 to activate T-cells, which can lead to better efficacy and safety compared to other T-cell engager antibodies. Jeng explains, "So why not just take two, let's say, monospecific...
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Leveraging Antibody Phage Display Library to Generate Unique Bispecific Antibodies for Solid Tumors with Dr. Jeng Her AP Biosciences
Empowered Patient Podcast
Dr. Jeng Her, Founder and CEO of AP Biosciences, is developing T-Cube bispecific antibodies that can target cancer cells and engage T-cells to kill them more effectively and safely than existing treatments. The company is focused on treating hard-to-treat cancers such as HER2-positive breast cancer, lung cancer, head and neck cancer, and pancreatic cancer. The T-Cube bispecific antibodies use CD137 instead of CD3 to activate T-cells, which can lead to better efficacy and safety compared to other T-cell engager antibodies. Jeng explains, "So why not just take two, let's say, monospecific...
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Increasing Focus of Medical Device Companies on Regulations and Compliance with Sonia Veluchamy Celegence TRANSCRIPT
Empowered Patient Podcast
Sonia Veluchamy, CEO and Co-founder of Celegence discusses the increasing regulatory requirements and complexities faced by the medical device industry. Celegence works with companies to streamline their regulatory data management processes and adopt advanced technology solutions to manage compliance efficiently. Medical device companies are often slower than pharmaceutical companies to recognize the need to invest in data governance and process optimization to maintain compliance and avoid fines, delays in product approval, and loss of market access. Sonia explains, "The awareness is there,...
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Increasing Focus of Medical Device Companies on Regulations and Compliance with Sonia Veluchamy Celegence
Empowered Patient Podcast
Sonia Veluchamy, CEO and Co-founder of Celegence discusses the increasing regulatory requirements and complexities faced by the medical device industry. Celegence works with companies to streamline their regulatory data management processes and adopt advanced technology solutions to manage compliance efficiently. Medical device companies are often slower than pharmaceutical companies to recognize the need to invest in data governance and process optimization to maintain compliance and avoid fines, delays in product approval, and loss of market access. Sonia explains, "The awareness is there,...
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Dissolvable Stent to Treat Peripheral Artery Disease Below the Knee with Dr. Ethan Korngold Abbott TRANSCRIPT
Empowered Patient Podcast
Dr. Ethan Korngold is the chief medical officer and divisional vice president of medical affairs at Abbott’s vascular business, which has developed a dissolvable stent technology to treat peripheral artery disease. PAD disproportionately affects Black and Hispanic communities and is often overlooked because early symptoms can be mistaken for other conditions. The Esprit BTK stent can help open up the smaller arteries below the knee and improve blood flow to the legs and feet to treat PAD and prevent severe complications and amputations. Ethan explains, "So peripheral artery disease...
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Dissolvable Stent to Treat Peripheral Artery Disease Below the Knee with Dr. Ethan Korngold Abbott
Empowered Patient Podcast
Dr. Ethan Korngold is the chief medical officer and divisional vice president of medical affairs at Abbott’s vascular business, which has developed a dissolvable stent technology to treat peripheral artery disease. PAD disproportionately affects Black and Hispanic communities and is often overlooked because early symptoms can be mistaken for other conditions. The Esprit BTK stent can help open up the smaller arteries below the knee and improve blood flow to the legs and feet to treat PAD and prevent severe complications and amputations. Ethan explains, "So peripheral artery disease...
info_outlineYoona Kim, CEO of Arine, a medication intelligence company, works with health plans and payers to ensure safe and effective medication therapy for patients. The Arine platform addresses polypharmacy, medication mismanagement, drug interactions, and proper dosing. Using AI and integrated databases, Arine is identifying patients who would benefit from medication management and shifting from reactive to proactive and preventative care.
Yoona explains, "Our clients are health plans and risk-bearing providers. So these are the payers of the healthcare system, those who bear the financial burden of healthcare costs because medications can be very powerful, they can cure, or they can lead to detrimental consequences and even unnecessary fatalities and high-cost events like hospitalizations. So it's important to these customers to make sure that their members are on the right medications to avoid these unnecessary clinical and financial outcomes."
"I think it pertains to all of these situations. One of our biggest problems in healthcare is that 66% of Americans are on some prescription drugs, and in fact, more than 50% use more than three drugs a year. We need to search through a population and find who would benefit from a medication change with the population-based approach. This is why we spent so much time at Arine building our patient targeting model to identify in which patients would a small medication change lead to a difference in outcomes."
"We're looking through all that patient's data, their medication history, their medical history, their demographics, and what their current clinical social, and behavioral risk factors are so we can identify that they're on the best medications, the safest and most effective for where they are in their health trajectory today. And, of course, the challenge is that their patient evolving health needs constantly change over time. On top of that, we have new medications being approved constantly and new advances being made. Our platform puts all this information together so that we can ensure that the best medication regimen is prescribed to the patients."
#Arine #Medication #MedicationManagement #MedicationMismanagement #Prescription #SDOH #ArtificialIntelligence #Polypharmacy #Deprescribing #Overprescribing #MedicationAdherence
