Driving Healthcare Not Sick Care Through an Integrated Approach with James Keppel Sarana Health TRANSCRIPT
Release Date: 08/04/2025
Developing Immunotherapy to Fight Bone Cancer with Paul Romness and Olivia Egge OS Therapies TRANSCRIPT
Empowered Patient Podcast
Paul Romness, Chairman, CEO, and President of OS Therapies, and Olivia Egge, a member of the Board of Directors of OS Therapies, discuss osteosarcoma, a rare and aggressive form of bone cancer that primarily affects teenagers. OS Therapies is developing an immunotherapy that utilizes a weakened form of the listeria bacteria to stimulate the immune system and prevent the spread of cancer cells to the lungs and brain. Olivia's experience as a patient has motivated her to advocate for better treatment options and join the board of OS Therapeutics. Paul explains, "So osteosarcoma is quite...
info_outline
Developing Immunotherapy to Fight Bone Cancer with Paul Romness and Olivia Egge OS Therapies
Empowered Patient Podcast
Paul Romness, Chairman, CEO, and President of OS Therapies, and Olivia Egge, a member of the Board of Directors of OS Therapies, discuss osteosarcoma, a rare and aggressive form of bone cancer that primarily affects teenagers. OS Therapies is developing an immunotherapy that utilizes a weakened form of the listeria bacteria to stimulate the immune system and prevent the spread of cancer cells to the lungs and brain. Olivia's experience as a patient has motivated her to advocate for better treatment options and join the board of OS Therapeutics. Paul explains, "So osteosarcoma is quite...
info_outline
New Inhibitor Drug Transforms Cancer Treatment Accessibility with Dan Schmitt Actuate Therapeutics TRANSCRIPT
Empowered Patient Podcast
Dan Schmitt, President and CEO of Actuate Therapeutics, is developing a cancer therapy that inhibits GSK3β, a key enzyme that is hijacked in cancer cells to drive tumor growth. Inhibiting this enzyme can impact the cancer cells and stimulate an immune response against the tumor. Actuate selected metastatic pancreatic cancer as their first target due to unmet need and promising data for their lead drug candidate. This could represent a significant advancement in the treatment of metastatic pancreatic cancer, offering a new standard-of-care option. Dan explains, "So, GSK-3β is a known...
info_outline
New Inhibitor Drug Transforms Cancer Treatment Accessibility with Dan Schmitt Actuate Therapeutics
Empowered Patient Podcast
Dan Schmitt, President and CEO of Actuate Therapeutics, is developing a cancer therapy that inhibits GSK3β, a key enzyme that is hijacked in cancer cells to drive tumor growth. Inhibiting this enzyme can impact the cancer cells and stimulate an immune response against the tumor. Actuate selected metastatic pancreatic cancer as their first target due to unmet need and promising data for their lead drug candidate. This could represent a significant advancement in the treatment of metastatic pancreatic cancer, offering a new standard-of-care option. Dan explains, "So, GSK-3β is a known...
info_outline
Democratizing Molecular Diagnostics Transforming Transplant Success with Andrea James iMDx TRANSCRIPT
Empowered Patient Podcast
Andrea James, Chief Financial Officer at iMDx, is focused on expanding access to innovative molecular diagnostic testing staring with a test for monitoring transplanted organ health. The test measures the donor-derived cell-free DNA which can indicate the need for drugs to target organ rejection before invasive procedures are required. The company is developing a kit-based version of the test that can be run by hospitals rather than relying on centralized labs, to increase access to this diagnostic and improve transplant outcomes. Andrea explains, "We changed our name on June 17th from...
info_outline
Democratizing Molecular Diagnostics Transforming Transplant Success with Andrea James iMDx
Empowered Patient Podcast
Andrea James, Chief Financial Officer at iMDx, is focused on expanding access to innovative molecular diagnostic testing staring with a test for monitoring transplanted organ health. The test measures the donor-derived cell-free DNA which can indicate the need for drugs to target organ rejection before invasive procedures are required. The company is developing a kit-based version of the test that can be run by hospitals rather than relying on centralized labs, to increase access to this diagnostic and improve transplant outcomes. Andrea explains, "We changed our name on June 17th from...
info_outline
Healthcare Financial Recovery Driven by Focus on People First with James Hereford Fairview Health Services TRANSCRIPT
Empowered Patient Podcast
James Hereford, President and CEO of Fairview Health Services, describes this Minnesota-based healthcare system's $600 million turnaround and the importance of focusing on people and processes, not just technology changes. Addressing staff shortages, quality of care, and patient experience led to finding a holistic approach that improved financial outcomes and changed the culture in a sustainable way. Investments have been made in community programs like food access and vaccination events, recognizing the impact of social determinants of health on patient outcomes. James explains, "When doing...
info_outline
Healthcare Financial Recovery Driven by Focus on People First with James Hereford Fairview Health Services
Empowered Patient Podcast
James Hereford, President and CEO of Fairview Health Services, describes this Minnesota-based healthcare system's $600 million turnaround and the importance of focusing on people and processes, not just technology changes. Addressing staff shortages, quality of care, and patient experience led to finding a holistic approach that improved financial outcomes and changed the culture in a sustainable way. Investments have been made in community programs like food access and vaccination events, recognizing the impact of social determinants of health on patient outcomes. James explains, "When doing...
info_outline
Innovative Homeostasis Focused Drugs to Treat Root Causes of Disease with Steve Butts Arrivo BioVentures TRANSCRIPT
Empowered Patient Podcast
teve Butts, Co-Founder and CEO of Arrivo BioVentures, is a biopharmaceutical company focused on developing therapies that target the root causes of disease rather than just treating the symptoms. Their drugs treat major depressive disorder and acute pancreatitis through novel epigenetic mechanisms of action. Sex-based differences were observed in clinical trials where the drug SP-624 showed efficacy in females but not in males, which could lead to a paradigm shift in how depression is treated in men and women. Steve explains, "We've evolved over time at Arrivo and with our previous companies....
info_outline
Innovative Homeostasis Focused Drugs to Treat Root Causes of Disease with Steve Butts Arrivo BioVentures
Empowered Patient Podcast
Steve Butts, Co-Founder and CEO of Arrivo BioVentures, is a biopharmaceutical company focused on developing therapies that target the root causes of disease rather than just treating the symptoms. Their drugs treat major depressive disorder and acute pancreatitis through novel epigenetic mechanisms of action. Sex-based differences were observed in clinical trials where the drug SP-624 showed efficacy in females but not in males, which could lead to a paradigm shift in how depression is treated in men and women. Steve explains, "We've evolved over time at Arrivo and with our previous...
info_outlineJames Keppel, Founder and CEO of Sarana Health, is focused on an integrated healthcare model that addresses chronic health challenges and preventative care. By providing personalized care, advanced lab testing, and one-on-one coaching with healthcare professionals, Sarana aims to fill the gaps in the traditional healthcare system, which often focuses on sick care rather than keeping people healthy. The company's integrated care model looks at the interconnected body systems to identify underlying causes of health issues, rather than just treating symptoms.
James explains, "What we provide is a totally personalized client-led and client-centric approach to wellness. We do that through an advanced series of lab tests and also you get to actually talk to the people who care for you, which I know is rare. Everything is very much about you and the person that you are, as opposed to charts and graphs about past history and that sort of thing with other doctors. So we get very dialed into the person."
"We've got a lot of different ranges that we can hit. So you mentioned people with chronic conditions. Yes, absolutely. We can deal with that. A lot of times, those people have not gotten any good answers from the legacy healthcare system. So they go and see their doctor every six months. They do the same test, they get the same, we don't know what's going on, or it's just you're older and that's the way it is, sort of thing. And then the other end of the spectrum is on the preventative side and looking at being in front of your health as opposed to waiting until you have a problem, which unfortunately the legacy healthcare system kind of does - they wait till you have a problem, they give you a prescription, and tell you, that's the way it goes. Whereas if you're on the preventive end, the easiest way to stay healthy is to never get sick."
#SaranaHealth #IntegratedHealth #Wellness #OptimalWellness #Wholebody #PersonalizedHealth
