Developing Accessible Virus-Specific T-Cell Therapies to Treat Solid Tumors with Dr. Ivan Horak Tikva Allocell
Release Date: 03/12/2026
Empowered Patient Podcast
Tom Looby, CEO of Conavi, is focused on developing hybrid intravascular imaging technology that combines two established modalities into a single imaging catheter to provide a comprehensive view of the coronary arteries. This eliminates blind spots when using either intravascular ultrasound (IVUS) or optical coherence tomography (OCT) alone and is driving a shift away from relying solely on traditional angiography toward the use of advanced intravascular imaging to guide coronary procedures. Using AI to analyze dual-stream co-registered data allows interventional cardiologists to more...
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Tom Looby, CEO of Conavi, is focused on developing hybrid intravascular imaging technology that combines two established modalities into a single imaging catheter to provide a comprehensive view of the coronary arteries. This eliminates blind spots when using either intravascular ultrasound (IVUS) or optical coherence tomography (OCT) alone and is driving a shift away from relying solely on traditional angiography toward the use of advanced intravascular imaging to guide coronary procedures. Using AI to analyze dual-stream co-registered data allows interventional cardiologists to more...
info_outlineEmpowered Patient Podcast
Theresa Lyons, CEO and Founder of Navigating AWEtism, is providing parents with current, accurate information about autism to help them focus on manageable issues for their child. She strongly cautions about information about autism from social media, which is often over-generalized and incorrect. Autism spectrum disorder presents a wide range of behaviors from mild communication difficulties to complex challenges requiring lifelong care, and Theresa advocates for an individual approach, including lab testing, before choosing a treatment plan. Theresa explains, "What we strive to do is...
info_outlineEmpowered Patient Podcast
Theresa Lyons, CEO and Founder of Navigating AWEtism, is providing parents with current, accurate information about autism to help them focus on manageable issues for their child. She strongly cautions about information about autism from social media, which is often over-generalized and incorrect. Autism spectrum disorder presents a wide range of behaviors from mild communication difficulties to complex challenges requiring lifelong care, and Theresa advocates for an individual approach, including lab testing, before choosing a treatment plan. Theresa explains, "What we strive to do is...
info_outlineEmpowered Patient Podcast
Lori Runion, a director at Resultant, identifies inadequate scheduling and related staffing unpredictability as a central cause of clinician burnout. Healthcare organizations traditionally rely on historical averages for scheduling, often resulting in a mismatch between patient demand and clinician capacity. Breaking down data silos and using analytics and AI to create predictive staffing models can help forecast demand, anticipate seasonal spikes, and enable proactive staffing to reduce clinician burnout. Lori explains, " From my perspective, burnout is driven at the operational level. To say...
info_outlineEmpowered Patient Podcast
Lori Runion, a director at Resultant, identifies inadequate scheduling and related staffing unpredictability as a central cause of clinician burnout. Healthcare organizations traditionally rely on historical averages for scheduling, often resulting in a mismatch between patient demand and clinician capacity. Breaking down data silos and using analytics and AI to create predictive staffing models can help forecast demand, anticipate seasonal spikes, and enable proactive staffing to reduce clinician burnout. Lori explains, " From my perspective, burnout is driven at the operational level. To say...
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Bill Heller, Chief Operating Officer at CHG Healthcare, is focused on the significant and growing demand for physicians across numerous specialties and on providing a flexible solution for healthcare facilities to maintain services with temporary physician staffing. Rural healthcare facilities are especially dependent on temporary staffing to overcome challenges in attracting and keeping permanent medical professionals. Physicians at all career stages are drawn to locum tenens work, and it has evolved from a niche practice to a mainstream strategy for healthcare facilities and...
info_outlineEmpowered Patient Podcast
Bill Heller, Chief Operating Officer at CHG Healthcare, is focused on the significant and growing demand for physicians across numerous specialties and on providing a flexible solution for healthcare facilities to maintain services with temporary physician staffing. Rural healthcare facilities are especially dependent on temporary staffing to overcome challenges in attracting and keeping permanent medical professionals. Physicians at all career stages are drawn to locum tenens work, and it has evolved from a niche practice to a mainstream strategy for healthcare facilities and...
info_outlineEmpowered Patient Podcast
Jean-Philippe Vert, the Co-Founder and CEO of Bioptimus, is building a foundational AI model for biology to solve the problem of siloed biomedical research. Key goals are to bridge the translational gaps between drug discovery and development, and between clinical research and real-world patient outcomes, and to redesign clinical trials for greater efficiency and improved results. Creating digital twins of patients is a way to simulate treatment outcomes and create synthetic control arms for clinical trials, ultimately lowering the risk and cost of drug development and enabling the creation...
info_outlineEmpowered Patient Podcast
Jean-Philippe Vert, the Co-Founder and CEO of Bioptimus, is building a foundational AI model for biology to solve the problem of siloed biomedical research. Key goals are to bridge the translational gaps between drug discovery and development, and between clinical research and real-world patient outcomes, and to redesign clinical trials for greater efficiency and improved results. Creating digital twins of patients is a way to simulate treatment outcomes and create synthetic control arms for clinical trials, ultimately lowering the risk and cost of drug development and enabling the creation...
info_outlineDr. Ivan Horak, Founder and CEO of Tikva Allocell, is focused on next-generation allogeneic cell therapies using modified T-cells from healthy donors to make these therapies more scalable, accessible, and affordable. Using virus-specific T-cells, this approach is showing effectiveness against solid tumors, which are difficult for traditional CAR-T therapies to treat. The primary target is an antigen found particularly in Epstein-Barr virus-associated malignancies and is showing potential for treating autoimmune diseases as well as cancer.
Ivan explains, "Cell therapy has a long history. We started with many scientists, but probably the godfather of the technology, Zelig Eshhar, who's not with us anymore. He passed away last year. The idea behind that was to use patient cells and modify them and use them as a fighter against the cancer. But over time, we realized over the last two decades that it's very useful, very successful in the treatment of hematologic malignancies, but it's very expensive and labor-intensive. The question was how to enhance this technology and bring it to more patients in a friendly and affordable way."
"The second generation are therapies where we are using healthy people's cells, primarily T-cells, but can be NK cells, can be gamma-delta T-cells. And these cells are being modified, and they are infused into a patient. The advantage of this technology is that patients are identified, and the provider can request the cell from different biotechnology companies, which can be available within the next few days, because from one healthy donor, you can make multiple doses for patients."
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