Cows Producing Human Antibodies for a New Type 1 Diabetes Treatment with Samuel Reich SAB Bio
Release Date: 09/17/2026
Bridging the Veterans Healthcare Access Gap with Ross Donahue Guardian Recovery TRANSCRIPT
Empowered Patient Podcast
Ross Donahue, Chief Administrative Officer at Guardian Recovery, highlights the dangerous gap between the time veterans request medical treatment, particularly for mental health and substance abuse issues, and actually receiving the necessary care. Guardian Recovery is addressing the need to treat mental health crises by deploying a 24/7 response with availability of beds and in partnership with other community service providers. Ross emphasizes that veterans are a diverse community, often with multimorbidities, and that reducing delays in accessing care could save lives and prevent...
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Bridging the Veterans Healthcare Access Gap with Ross Donahue Guardian Recovery
Empowered Patient Podcast
Ross Donahue, Chief Administrative Officer at Guardian Recovery, highlights the dangerous gap between the time veterans request medical treatment, particularly for mental health and substance abuse issues, and actually receiving the necessary care. Guardian Recovery is addressing the need to treat mental health crises by deploying a 24/7 response with availability of beds and in partnership with other community service providers. Ross emphasizes that veterans are a diverse community, often with multimorbidities, and that reducing delays in accessing care could save lives and prevent...
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Using Precision Routing to Match Patients with the Right Specialist with Andy Parham Brado AI TRANSCRIPT
Empowered Patient Podcast
Andy Parham, Chief Executive Officer at Brado AI, has developed an AI platform that acts as an orchestration layer between patient demand and health system capacity. The platform uses conversational AI and precision routing to match patients to the appropriate provider, reducing time to reaching the correct treatment. Utilizing this approach also provides an opportunity to optimize the use of existing clinical resources, enabling providers to work more productively without requiring additional hiring or infrastructure. Andy explains, "We think of our platform as the orchestrator...
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Using Precision Routing to Match Patients with the Right Specialist with Andy Parham Brado AI
Empowered Patient Podcast
Andy Parham, Chief Executive Officer at Brado AI, has developed an AI platform that acts as an orchestration layer between patient demand and health system capacity. The platform uses conversational AI and precision routing to match patients to the appropriate provider, reducing time to reaching the correct treatment. Utilizing this approach also provides an opportunity to optimize the use of existing clinical resources, enabling providers to work more productively without requiring additional hiring or infrastructure. Andy explains, "We think of our platform as the orchestrator...
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How Hospitals Are Fighting Back Against AI-Driven Claim Denials with Brian Kenah EnableComp TRANSCRIPT
Empowered Patient Podcast
Brian Kenah, Chief Technology Officer at EnableComp, specializes in complex claims and has developed an AI plaform boosting efficiency and quality by incorporating new codes and regulatory changes while learning from approval and denial patterns. The ability to deliver predictive revenue intelligence enables hospitals to identify issues before claims are submitted, prevent denials and negotiate better payer contracts using data-driven insights. The need for this solution is in part a result of the use of AI by payers which have increasingly deployed AI to accelerate claims denials and...
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How Hospitals Are Fighting Back Against AI-Driven Claim Denials with Brian Kenah EnableComp
Empowered Patient Podcast
Brian Kenah, Chief Technology Officer at EnableComp, specializes in complex claims and has developed an AI plaform boosting efficiency and quality by incorporating new codes and regulatory changes while learning from approval and denial patterns. The ability to deliver predictive revenue intelligence enables hospitals to identify issues before claims are submitted, prevent denials and negotiate better payer contracts using data-driven insights. The need for this solution is in part a result of the use of AI by payers which have increasingly deployed AI to accelerate claims denials and...
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Protecting Against Healthcare Workplace Violence with Jeanne Vennella Canopy TRANSCRIPT
Empowered Patient Podcast
Jeanne Vennella, Clinical Strategy Director at Canopy, shines a light on workplace violence in healthcare and the need to recognize the problem and implement solutions to reduce risk. The majority of violent incidents originate with patients, families, and visitors, often triggered by poor communication and the stress of receiving difficult news. Canopy offers a wearable duress button worn behind a staff member's ID badge, allowing discreet and immediate alerts to security and providing actionable intelligence to enable proactive security measures. Jeanne explains, "Workplace violence has...
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Protecting Against Healthcare Workplace Violence with Jeanne Vennella Canopy
Empowered Patient Podcast
Jeanne Vennella, Clinical Strategy Director at Canopy, shines a light on workplace violence in healthcare and the need to recognize the problem and implement solutions to reduce risk. The majority of violent incidents originate with patients, families, and visitors, often triggered by poor communication and the stress of receiving difficult news. Canopy offers a wearable duress button worn behind a staff member's ID badge, allowing discreet and immediate alerts to security and providing actionable intelligence to enable proactive security measures. Jeanne explains, "Workplace violence has...
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Neurostimulation Therapy for Stroke Rehabilitation with Richard Foust Mobia Medical TRANSCRIPT
Empowered Patient Podcast
Richard Foust, President and CEO of Mobia Medical, discusses their FDA-approved implantable neurostimulation technology designed to improve hand and arm function in ischemic stroke survivors. When paired with task-specific rehabilitation therapy, this process enhances neuroplasticity, allowing the brain to form stronger neural connections around areas affected by stroke. With clinical results showing durable, meaningful improvements, the American Heart Association and American Stroke Association have included Mobia Medical in their guidelines for adult stroke rehabilitation and...
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Neurostimulation Therapy for Stroke Rehabilitation with Richard Foust Mobia Medical
Empowered Patient Podcast
Richard Foust, President and CEO of Mobia Medical, discusses their FDA-approved implantable neurostimulation technology designed to improve hand and arm function in ischemic stroke survivors. When paired with task-specific rehabilitation therapy, this process enhances neuroplasticity, allowing the brain to form stronger neural connections around areas affected by stroke. With clinical results showing durable, meaningful improvements, the American Heart Association and American Stroke Association have included Mobia Medical in their guidelines for adult stroke rehabilitation and...
info_outlineSamuel Reich, Chief Executive Officer at SAB Bio, is developing a fully human antibody therapy designed to transform type 1 diabetes treatment by preserving patients' beta cells and their ability to produce insulin, rather than just managing symptoms with insulin and glucose monitoring. The drug is produced using the company's bovine platform which uses genetically modified cows to generate human immunoglobulins offering a safer more scalable alternative to rabbit-derived therapies. If successful, this approach could represent a functional cure, potentially transforming type 1 diabetes from a disease requiring daily insulin management to one requiring only periodic infusions.
Samuel explains, "Our mission at SAB Bio is to transform what it means to get a type 1 diabetes diagnosis by changing the course of the disease, and not just treating the symptoms, with our new medicine, which is called SAB-142. Why type 1 diabetes? It's a major global unmet medical need that has largely been underserved in research until recently."
"Insulin and glucose monitoring are the standard of care, but they don't treat the disease. They don't treat the patient's illness. They just manage the symptoms and allow the patient to survive. So, they're essential, but they're not helping the patient be healthier or manage the disease process. Our mission is to treat the disease causing type 1 diabetes by saving the patient's beta cells and saving the patient's ability to make their own insulin. And exogenous insulin is no substitute for the patient's own ability to make insulin."
"So we have a platform at SAB called the TcBovine, which is a transchromosomal bovine. And these are cows that are healthy and happy cows that look like normal dairy cows, but the cows make human IgG, or human antibodies, instead of cow IgG. And we vaccinate our cows with human thymocytes and purify the IgG from the cow plasma. And our drug is a fully human immunoglobulin, which targets human thymocytes. So, it does what the rabbit drug does, thymoglobulin, but it's human and can be given more safely without making the patient sick, and can be given for the life of the patient to continue to preserve their beta cells for the long term."
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