History of Eosinophils with Dr. Gerald Gleich
Real Talk: Eosinophilic Diseases
Release Date: 01/25/2022
The Spoon Theory and Eosinophilic Disorders
Real Talk: Eosinophilic Diseases
Co-host Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and co-host Holly Knotowicz, a speech-language pathologist living with EoE, who serves on APFED’s Health Sciences Advisory Council, have a conversation about the Spoon Theory. In this episode, Ryan and Holly discuss the origin of the Spoon Theory, their experiences, and what the Spoon Theory means in their lives. Listen to this episode to learn how the Spoon Theory could work for you. Disclaimer: The information provided in this podcast is designed to...
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Gastro Girl and GI Diseases: Conversation With Jacqueline Gaulin
Real Talk: Eosinophilic Diseases
Description: Co-host Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and co-host Holly Knotowicz, a speech-language pathologist living with EoE, who serves on APFED’s Health Sciences Advisory Council, speak with Jacqueline Gaulin, the Founder of Gastro Girl, a source of information for people living with various gastrointestinal disorders. In this episode, Ryan and Holly interview Jacqueline Gaulin about her career, how she started Gastro Girl, its podcast, and the partnership between Gastro Girl, the American College...
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The Family Risk of Eosinophilic Gastrointestinal Diseases
Real Talk: Eosinophilic Diseases
Description: Co-host Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and co-host Mary Jo Strobel, APFED’s Executive Director, speak with Dr. Kathryn Peterson, MD, MSCI, a Professor of Gastroenterology at the University of Utah Health. In this episode, Ryan and Mary Jo interview Dr. Peterson about the family risk of eosinophilic gastrointestinal diseases, discussing the studies she has done, future work she is planning, and other studies of related topics. She shares that she is a parent to a patient living with an...
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Remodeling and Eosinophilic Esophagitis (EoE)
Real Talk: Eosinophilic Diseases
Description: Co-host Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and co-host Holly Knotowicz, a speech-language pathologist living with EoE, who serves on APFED’s Health Sciences Advisory Council, speak with Dr. Amanda Muir, an Assistant Professor of Pediatrics at the Children’s Hospital of Philadelphia. In this episode, Ryan and Holly interview Dr. Muir about tissue remodeling and eosinophilic esophagitis (EoE). Dr. Muir describes remodeling and stiffening, its effects, and how it relates to treatment and...
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Journey to an Eosinophilic Esophagitis (EoE) Diagnosis
Real Talk: Eosinophilic Diseases
Description: Co-host Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and co-host Holly Knotowicz, a speech-language pathologist living with EoE, who serves on APFED’s Health Sciences Advisory Council, speak with Moises Velasquez-Manoff, a health and science writer living with EoE. He is a contributing writer for the New York Times Magazine. He writes about the human microbiome and its impact on health, as well as climate, COVID-19, and other health and science topics. In this episode, Ryan and Hollyinterview Moises...
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Community Perspective: Eosinophilic Gastritis (EoG)
Real Talk: Eosinophilic Diseases
Description: Co-host Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and co-host Mary Jo Strobel, APFED’s Executive Director, speak with Dr. Jenny Huang, an allergy and immunology fellow at Scripps Clinic, who has a unique perspective of also living with eosinophilic gastritis (EoG). In this episode, Ryan and Mary Jo interview Dr. Jenny Huang about various EGIDs, her allergy and immunology fellowship, her EoG diagnosis, and the elimination diet she follows to treat her EoG. Dr. Huang speaks about patients she sees,...
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Community Perspective: Eosinophilic Esophagitis
Real Talk: Eosinophilic Diseases
Description: Co-host Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist and feeding specialist living with EoE, who serves on APFED’s Health Sciences Advisory Council, talk with Declan, a teenager living with eosinophilic esophagitis. In this episode, Ryan and Holly interview Declan about his EoE diagnosis, his dietary restrictions, how he receives support from his parents and friends, and upcoming milestones such as transitioning clinical care to an adult provider and...
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Esophageal String Test: Monitoring Tool Use and Development
Real Talk: Eosinophilic Diseases
Description: Co-host Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist and feeding specialist living with EoE who serves on APFED’s Health Sciences Advisory Council, talk with Drs. Robin Shandas and Steven Ackerman, are scientists who work together at EnteroTrack. In this episode, Ryan and Holly interview Drs. Shandas and Ackerman about the development of the esophageal string test (EST), or simply the string test. They discuss the initial concept and the work that led...
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Live from APFED’s EOS Connection 2023
Real Talk: Eosinophilic Diseases
Description: Ryan Piansky, a college student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech pathologist living with EoE who specializes in feeding therapy and serves on APFED’s Health Sciences Advisory Council recorded this episode live at APFED’s annual patient education conference in Denver, CO. They shared their experiences with this year’s conference, discussed takeaways from the conference presentations, and offered ways to continue the conversation. Recordings of the conference presentations are available to...
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Proton Pump Inhibitors and EoE
Real Talk: Eosinophilic Diseases
Description: Co-host Mary Jo Strobel, APFED’s Executive Director, is joined by co-host Holly Knotowicz, a speech-language pathologist and feeding specialist living with eosinophilic esophagitis (EoE) who serves on APFED’s Health Sciences Advisory Council. They talk with guest Dr. James Franciosi, Chief of the Division of Gastroenterology, Hepatology, and Nutrition at Nemours Children’s Health in Orlando, Florida. In this episode, Mary Jo Strobel and Holly Knotowicz interview Dr. James Franciosi about his research with proton pump inhibitors, personalized medicine, the different factors...
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Co-host Beth Allen is the parent of a child who was diagnosed with eosinophilic gastrointestinal disease at a time when very little information about these conditions were available. She co-founded APFED in 2001 and is now serving as Senior Director of Strategic Sales at EvoEndo, which develops systems that enable unsedated endoscopic procedures.
In this episode, Dr. Gleich shares more about what sparked his interest in researching eosinophils and how he has contributed to various related research studies. He sheds light on his discovery of Gleich syndrome, some of the studies that have contributed to a better understanding of eosinophilic conditions and their treatment, and his hopes for further research in this area. Beth Allen also talks about the history of APFED and patient advocacy in relation to eosinophil-associated diseases, and how patients have contributed to research. Tune in to find out more.
Disclaimer: The information provided in this podcast is designed to support, not replace the relationship that exists between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.
Key Takeaways:
[1:08] Ryan introduces his co-host for this episode, Beth Allen.
[2:47] Ryan introduces the guest for this episode — Dr. Gerald Gleich.
[3:15] As a specialist in dermatology, how did Dr. Gleich get interested in researching eosinophils and related diseases?
[6:34] Where did Dr. Gleich’s research begin and how did his initial research play out?
[9:08] At what point did Dr. Gleich start seeing other eosinophilic cases or associated disorders?
[12:12] Dr. Gleich shares more about why eosinophils are named as such.
[16:21] Dr. Gleich discovered an eosinophil-associated disease called Gleich syndrome. How did he discover this condition?
[22:03] What did patient advocacy look like 20 years ago? Beth Allen shares how APFED got started and what things were like in the early days.
[31:03] How did Dr. Gleich get involved with APFED?
[34:08] Dr. Gleich shares a little about some of the studies that have been done around granule proteins and eosinophils.
[39:45] Dr. Gleich shares an anecdote of a patient who had a child while on eosinophil suppressing treatment.
[42:24] Despite advances being made in research in this area, there is still a lot that we don’t know and a lot more to learn. Patients have a huge role to play in contributing to research about eosinophils.
[46:43] What are Dr. Gleich’s biggest hopes for research in the field of eosinophil-associated diseases going forward?
[52:32] What is Dr. Gleich currently working on?
[54:08] Dr. Gleich reflects on the importance of being ready and prepared for things we may not predict or expect in the future.
Mentioned in This Episode:
American Partnership for Eosinophilic Disorders (APFED)
APFED on YouTube, Twitter, Facebook, Pinterest, Instagram
2021 EOS Connection Patient Education Conference
EOS Connections Online Community
This episode is brought to you thanks to the support of our Education Partners: GlaxoSmithKline.
Tweetables:
“The eosinophil has its roots in Greek mythology, in German chemistry, and then in the wonderful insights that Ehrlich had to apply these dyes to tissues.” - Dr. Gleich
“The drive to discover the syndrome was really a matter of necessity.” - Dr. Gleich
“Advocacy in this community actually started with just trying to bring together education in a more uniform way [and] finding other avenues of support between us.” - Beth Allen
“The amount of support that came back from the simple asks that we had was surprising.” - Beth Allen