History of Eosinophils with Dr. Gerald Gleich
Real Talk: Eosinophilic Diseases
Release Date: 01/25/2022
Bone Mineral Density in Pediatric Eosinophilic Esophagitis
Real Talk: Eosinophilic Diseases
Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED’s Health Sciences Advisory Council, interview Anna Henderson, MD, a pediatric gastroenterologist at Northern Light Health in Maine, about bone mineral density in EoE patients. They discuss a paper she co-authored on the subject. Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship that exists between listeners...
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Common Nutritional Deficiencies that Affect Those with Non-EoE EGIDs
Real Talk: Eosinophilic Diseases
Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED’s Health Sciences Advisory Council, interview Bethany Doerfler, MS, RDN, a clinical research dietician specializing in lifestyle management of digestive diseases at Northwestern Medicine. Ryan and Holly discuss managing nutritional deficiencies in patients with non-EoE EGIDs and a study Bethany worked on. Disclaimer: The information provided in this podcast is...
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Comparing Pediatric and Adult EoE
Real Talk: Eosinophilic Diseases
Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED’s Health Sciences Advisory Council, interview Dr. Melanie Ruffner, an Attending Physician with the Division of Allergy and Immunology and the Center for Pediatric Eosinophilic Disorders at Children’s Hospital of Philadelphia. Dr. Ruffner describes her work in clinic and the paper she co-authored about pediatric and adult eosinophilic esophagitis (EoE). She covers...
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Full Circle: An Immunologist’s Unexpected EoE Journey
Real Talk: Eosinophilic Diseases
Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED’s Health Sciences Advisory Council, interview Dr. John Accarino, an allergist and immunologist at Massachusetts General Hospital and Mass General for Children, on the topic of immunology support for eosinophilic esophagitis (EoE). Dr. Accarino shares his experiences as a person living with food allergies, allergic asthma, peanut allergy, and eosinophilic...
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The Intersection of Food Allergy and Eosinophilic Esophagitis
Real Talk: Eosinophilic Diseases
Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED’s Health Sciences Advisory Council, interview Dr. Wayne Shreffler, Chief of Pediatric Allergy and Immunology and Co-Director of The Food Allergy Center at Massachusetts General Hospital. Dr. Shreffler is also an investigator at The Center for Immunology and Inflammatory Disease and The Food Allergy Science Initiative. His research is focused on understanding how...
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Guidelines for Childhood non-EoE EGIDs
Real Talk: Eosinophilic Diseases
Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED’s Health Sciences Advisory Council, interview Dr. Margaret Collins, a professor of pathology at the University of Cincinnati and a staff pathologist at Cincinnati Children’s Hospital Medical Center. Dr. Collins was a member of the task force that produced the Guidelines on Childhood EGIDs Beyond EoE. In this interview, Dr. Collins discusses the guidelines and how they were...
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Eosinophilic Fasciitis (EF), with Dr. Catherine Sims and Jason Ingraham
Real Talk: Eosinophilic Diseases
Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED’s Health Sciences Advisory Council, interview Jason Ingraham, an adult living with eosinophilic fasciitis (EF), and Dr. Catherine Sims, a rheumatologist at Duke University and a Health Services Research Fellow at the Durham Veterans’ Affairs Hospital. They discuss Jason’s experiences living with EF and Dr. Sims’s experience treating EF. They share Jason’s...
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The Evolution of Eosinophilic Gastrointestinal Disorders, with Dr. Dan Atkins
Real Talk: Eosinophilic Diseases
Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED’s Health Sciences Advisory Council, interview Dr. Dan Atkins about Children’s Hospital Colorado’s multidisciplinary treatment program for eosinophilic gastrointestinal disorders (EGIDs). In this episode, Ryan and Holly interview their friend, Dr. Dan Atkins. Ryan was a long-time patient of Dr. Atkins and Holly worked as a feeding specialist with Dr....
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Navigating Eosinophilic Esophagitis in College with Kate Goncalves
Real Talk: Eosinophilic Diseases
Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Mary Jo Strobel, APFED’s Executive Director, interview Kate Goncalves about her diagnosis and treatment journey with EoE. In this episode, Ryan and Mary Jo discuss with Kate Goncalves how she lived with her symptoms for years before finally bringing them to the attention of her primary care physician at age 16, and how she was connected with a gastroenterologist and diagnosed with EoE. Kate discusses her transition from pediatric to adult care, and how...
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Treating EoE as an Allergist with Dr. Priya Bansal
Real Talk: Eosinophilic Diseases
Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED’s Health Sciences Advisory Council, interview Dr. Priya Bansal about an allergist’s role in treating EoE. In this episode, Ryan and Holly discuss with Dr. Priya Bansal her career in internal medicine, pediatrics, allergies, and immunology. She emphasizes the importance of patient advocacy and encourages parents to not accept the diagnosis that their child...
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Co-host Beth Allen is the parent of a child who was diagnosed with eosinophilic gastrointestinal disease at a time when very little information about these conditions were available. She co-founded APFED in 2001 and is now serving as Senior Director of Strategic Sales at EvoEndo, which develops systems that enable unsedated endoscopic procedures.
In this episode, Dr. Gleich shares more about what sparked his interest in researching eosinophils and how he has contributed to various related research studies. He sheds light on his discovery of Gleich syndrome, some of the studies that have contributed to a better understanding of eosinophilic conditions and their treatment, and his hopes for further research in this area. Beth Allen also talks about the history of APFED and patient advocacy in relation to eosinophil-associated diseases, and how patients have contributed to research. Tune in to find out more.
Disclaimer: The information provided in this podcast is designed to support, not replace the relationship that exists between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.
Key Takeaways:
[1:08] Ryan introduces his co-host for this episode, Beth Allen.
[2:47] Ryan introduces the guest for this episode — Dr. Gerald Gleich.
[3:15] As a specialist in dermatology, how did Dr. Gleich get interested in researching eosinophils and related diseases?
[6:34] Where did Dr. Gleich’s research begin and how did his initial research play out?
[9:08] At what point did Dr. Gleich start seeing other eosinophilic cases or associated disorders?
[12:12] Dr. Gleich shares more about why eosinophils are named as such.
[16:21] Dr. Gleich discovered an eosinophil-associated disease called Gleich syndrome. How did he discover this condition?
[22:03] What did patient advocacy look like 20 years ago? Beth Allen shares how APFED got started and what things were like in the early days.
[31:03] How did Dr. Gleich get involved with APFED?
[34:08] Dr. Gleich shares a little about some of the studies that have been done around granule proteins and eosinophils.
[39:45] Dr. Gleich shares an anecdote of a patient who had a child while on eosinophil suppressing treatment.
[42:24] Despite advances being made in research in this area, there is still a lot that we don’t know and a lot more to learn. Patients have a huge role to play in contributing to research about eosinophils.
[46:43] What are Dr. Gleich’s biggest hopes for research in the field of eosinophil-associated diseases going forward?
[52:32] What is Dr. Gleich currently working on?
[54:08] Dr. Gleich reflects on the importance of being ready and prepared for things we may not predict or expect in the future.
Mentioned in This Episode:
American Partnership for Eosinophilic Disorders (APFED)
APFED on YouTube, Twitter, Facebook, Pinterest, Instagram
2021 EOS Connection Patient Education Conference
EOS Connections Online Community
This episode is brought to you thanks to the support of our Education Partners: GlaxoSmithKline.
Tweetables:
“The eosinophil has its roots in Greek mythology, in German chemistry, and then in the wonderful insights that Ehrlich had to apply these dyes to tissues.” - Dr. Gleich
“The drive to discover the syndrome was really a matter of necessity.” - Dr. Gleich
“Advocacy in this community actually started with just trying to bring together education in a more uniform way [and] finding other avenues of support between us.” - Beth Allen
“The amount of support that came back from the simple asks that we had was surprising.” - Beth Allen