Integrating Clinical Trials With the Practice of Medicine
Release Date: 06/03/2024
Zerlasiran, a Small-Interfering RNA That Targets Lipoprotein(a)
JAMA Author Interviews
Elevated lipoprotein(a) levels increase the risk of atherosclerotic cardiovascular disease (ASCVD) and aortic stenosis. Cleveland Clinic’s Steven E. Nissen, MD, speaks with JAMA Executive Editor Gregory Curfman, MD, about how zerlasiran...
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Intratracheal Budesonide for Extremely Preterm Infants
JAMA Author Interviews
Preterm birth is the greatest cause of neonatal mortality and morbidity, with infants born extremely preterm at highest risk. Author Brett J. Manley, PhD, the Royal Women’s Hospital, Melbourne, Australia, discusses a new study of the...
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Digital Health Behavior Intervention to Prevent Childhood Obesity
JAMA Author Interviews
Preventing obesity in early childhood is challenging for clinicians and families. Authors Eliana M. Perrin, MD, MPH, of Johns Hopkins University, and William J. Heerman, MD, MPH, of Vanderbilt University, join JAMA Deputy Editor Tracy...
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Drug Shortages After Supply Chain Issues in the US vs Canada
JAMA Author Interviews
A new study published in JAMA found that drug-related supply chain issue reports were 40% less likely to result in meaningful drug shortages in Canada compared with the US. Authors Kate Suda, PharmD, MS, of University of Pittsburgh School...
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Advanced Birth Centers Raise Safety Concerns for Obstetric Care
JAMA Author Interviews
In the US, childbirth typically occurs in hospitals or accredited birth centers. President of the American College of Obstetricians and Gynecologists Stella Marie Dantas, MD, speaks with JAMA Deputy Editor Linda Brubaker, MD, MS, about...
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Declaration of Helsinki Addresses New Ethical Challenges
JAMA Author Interviews
The Declaration of Helsinki originated in 1964, developed by the World Medical Association (WMA). Process Chair Jack S. Resneck Jr, MD, discusses the 2024 updates to the Declaration of Helsinki with JAMA Editor in Chief Kirsten...
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JAMA Critical Care Research at ESICM Congress 2024
JAMA Author Interviews
Transfusion strategy for patients with acute brain injury, telehealth care, acute kidney injury after cardiac surgery, and weaning ventilatory support are the topics of 4 trials published in JAMA and presented at the 2024 European Society...
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Fecal Immunochemical Test (FIT) and Helicobacter pylori Stool Antigen Co-Testing for Gastric Cancer
JAMA Author Interviews
Gastric cancer is a leading cause of cancer death globally. Chronic H pylori infection is the primary cause of gastric cancer, responsible for at least 80% of the new cases. Constanza Camargo, PhD, of the National Cancer Institute joins...
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Preventing Fever in Patients With Acute Vascular Brain Injury
JAMA Author Interviews
Fever is associated with worse outcomes in patients with stroke, but whether preventing fever improves outcomes is unclear. David M. Greer, MD, MA, speaks with JAMA Associate Editor Jeffrey L. Saver, MD, about fever prevention in patients...
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The Discovery of Glucagon-Like Peptide 1 (GLP-1)
JAMA Author Interviews
The 2024 Lasker–DeBakey Clinical Medical Research Award has been presented for the discovery of GLP-1 and its application to the treatment of obesity. Lasker winner Svetlana Mojsov, PhD, discusses her role in this innovative discovery and...
info_outlineRandomized clinical trials (RCTs) frequently fail to generate knowledge relevant to practice, while practice patterns are frequently unsupported by RCT evidence. Derek C. Angus, MD, MPH, of the University of Pittsburgh, joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss The Integration of Clinical Trials With the Practice of Medicine: Repairing a House Divided.
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