Psychedelics in Research & Practice | James W. Jesso ~ ATTMind 200
Release Date: 09/19/2025
Adventures Through The Mind
Psychotherapist Marc AixalΓ of ICEERS explains what psychedelic integration is, and what it isn't. Marc offers some metaphors to help psychedelic integration, his seven dimensions of integration, and outlines why each of these has to be custom tailored to the needs of the individual person. Marc also offers us his perspective as to why integration is not psychotherapy, and why it should end once the person no longer needs a practitioner. Finally, he makes the case that preparation matters even more than integration, because psychedelic healing is a process, not an event. (00:00) What...
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What is it actually like to take ibogaine? Jonathan Dickinson, CEO of Ambio Life Sciences and author of Ibogaine and the Bicameral Mind, takes us inside the flood dose: why you can't stand up for hours, why it's closer to a waking dream than a psychedelic trip, and what the people he's treated say they saw. We also get into the book's big ideas (Lacan's "the Real" and Julian Jaynes's bicameral mind), why the benefits can arrive even when nothing seems to happen, and the real medical risk, including deaths. π π Jonathan's book and work: Β· Ambio Life Sciences: π Sponsored by...
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Justin Townsend of MycoMeditations explains the "golden shadow" and why psychedelic facilitators need to be well-trained to hand that projection back rather than take it on. The dark shadow is the unsavory stuff we don't want to admit to: the shame, the disgust, the fear. The golden shadow, however, is the beautiful stuff about ourselves: our strengths, our creativity and our capacities for success. However, the golden shadow can get buried and projected just as much as the dark shadow. The way it shows up is as a kind of intense admiration for someone else. Putting them up on a pedestal,...
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This episode is going to explore the state of the psychedelic movement right now β the money, the policy, the ethics, and the stories that are not getting told. Specifically, we are going to be exploring what is actually happening across the so-called psychedelic renaissance: the for-profit pharmaceutical track, city and state level decriminalization, the unregulated market selling products that mostly do not contain what they claim to, the biopiracy question that almost nobody in mainstream media will ask about, and why one of the field's most trusted journalists says psychedelics are a...
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In this Adventures Through The Mind micro, I explain what MDMA is and why it makes us feel love. I explain why MDMA is an entactogen rather than a classic psychedelic, and how it floods the brain with serotonin. I also discuss how it raises our sense of safety, lowers our sense of danger, and drops the emotional boundaries we normally hold, which is what made it work in couples therapy. Finally, I cover the PTSD research, and why MDMA with someone new can leave you holding an intimacy you have not earned. (00:00) What MDMA is, and how it works in the brain (06:25) Love with a capital L...
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This episode of the podcast is going to explore what actually happens inside psilocybin assisted therapy, from the first conversation to the last integration session. Specifically, we are going to be walking the entire arc of a legal psilocybin therapy engagement through the lens of naturopathic medicine: preparation, the session itself, integration, the risks, and how to tell whether any of it is right for you. Our guest is Dr. JJ Pursell. What You'll Learn About: πΏ What naturopathic medicine actually is, and how its root-cause approach differs from the conventional model π What...
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Is your attention being trained the same way an algorithm is trained? In this micro, Carl Hayden Smith joins me to unpack what he calls the attention war: how algorithms and short-form media shape the brain toward ADHD-like patterns, whether you have ADHD or not. We also talk about what surfaces in the mind after a few phone-free days, and why Carl believes AI's real danger isn't sentience, but a mass hallucination of it: one that's already changing how we see ourselves. Watch this MICRO on This is a clip from 'Hyperhumanism: Reclaiming Our Humanity in the Age of AI | Carl Hayden Smith',...
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Leonardo Mercado, known as The Peyote Lorax, joins me for Episode 209 to talk about the ecological and legal crisis threatening peyote, the sacred cactus at the center of Native American Church ceremonies. We get into peyote's collapse in its only natural range, the contradictions inside the federal exemption that governs who can legally possess and cultivate it, and the Seed to Ceremony conservation project Leo is building through Morningstar Conservancy in Arizona. π ποΈThe Morningstar Conservancy: The Peyote Lorax's website: Check Out Leo on Instagram: ...
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Ibogaine is regularly categorized as a psychedelic β but that label may be misleading in ways that matter. In this micro, James offers a crash course in what ibogaine actually is: where it comes from, how its unusual pharmacology works, what it does to the mind, and why it holds a position in addiction medicine that no other drug on earth can claim. The risk profile is part of the picture too. This is a clip from 'Psychedelics in Research & Practice | James W. Jesso', Adventures Through The Mind Podcast, episode 200 FULL EPISODE MORE IBOGAINE EPISODES SUPPORT THE PODCAST π₯° ...
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You can buy Lanmaoa asiatica at a food market in Yunnan. Cook it thoroughly and it's just a bolete. Undercook it, and roughly 12 to 24 hours later you may spend the next three to seven days seeing hyper-realistic miniature people moving through your environment β documented across three independent cultures, mechanism completely unknown. Ethnobotanist Colin Domnauer (Dentinger Lab, Natural History Museum of Utah) is one of the few people actively trying to understand why. Colin and I get into what's actually documented about Lanmaoa asiatica β the three independent cultural accounts, the...
info_outlineWe are doing something special in celebreation of episode 200. Instead of an interview, I recorded a straight-talk lecture on psychedelics.
Together, we are going to explore what psychedelics are; why they are so interesting to research; and the chemistry, pharmacology, phenomenology, history, and current research on Psilocybin, DMT, MDMA, Ketamine, and Ibogaine.
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π BUY MY BOOKS: DECOMPOSING THE SHADOW: LESSONS FROM THE PSILOCYBIN MUSHROOM | THE TRUE LIGHT OF DARKNESS
FULL TOPICS BREAKDOWN BELOW
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Episode Breakdown
- (00:00) Opening
- (00:47) Introduction
- (08:07) Lecture Begins
- (13:30) What is a psychedelic
- (27:53) What makes psychedelics so interesting to research
- (37:18) Splitters vs Lumpers
- (39:01) Psilocybin (magic mushrooms)
- (59:50) DMT
- (1:07:08) Ayahuasca
- (1:13:21) MDMA
- (1:39:51) Patreon Thanks
- (1:44:24) Ketamine
- (2:04:58) Ibogaine (Iboga)
- (2:36:27) Outro