Psychedelics in Research & Practice | James W. Jesso ~ ATTMind 200
Release Date: 09/19/2025
Adventures Through The Mind
This episode of the podcast is going to explore what actually happens inside psilocybin assisted therapy, from the first conversation to the last integration session. Specifically, we are going to be walking the entire arc of a legal psilocybin therapy engagement through the lens of naturopathic medicine: preparation, the session itself, integration, the risks, and how to tell whether any of it is right for you. Our guest is Dr. JJ Pursell. What You'll Learn About: πΏ What naturopathic medicine actually is, and how its root-cause approach differs from the conventional model π What...
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Is your attention being trained the same way an algorithm is trained? In this micro, Carl Hayden Smith joins me to unpack what he calls the attention war: how algorithms and short-form media shape the brain toward ADHD-like patterns, whether you have ADHD or not. We also talk about what surfaces in the mind after a few phone-free days, and why Carl believes AI's real danger isn't sentience, but a mass hallucination of it: one that's already changing how we see ourselves. Watch this MICRO on This is a clip from 'Hyperhumanism: Reclaiming Our Humanity in the Age of AI | Carl Hayden Smith',...
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Leonardo Mercado, known as The Peyote Lorax, joins me for Episode 209 to talk about the ecological and legal crisis threatening peyote, the sacred cactus at the center of Native American Church ceremonies. We get into peyote's collapse in its only natural range, the contradictions inside the federal exemption that governs who can legally possess and cultivate it, and the Seed to Ceremony conservation project Leo is building through Morningstar Conservancy in Arizona. π ποΈThe Morningstar Conservancy: The Peyote Lorax's website: Check Out Leo on Instagram: ...
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Ibogaine is regularly categorized as a psychedelic β but that label may be misleading in ways that matter. In this micro, James offers a crash course in what ibogaine actually is: where it comes from, how its unusual pharmacology works, what it does to the mind, and why it holds a position in addiction medicine that no other drug on earth can claim. The risk profile is part of the picture too. This is a clip from 'Psychedelics in Research & Practice | James W. Jesso', Adventures Through The Mind Podcast, episode 200 FULL EPISODE MORE IBOGAINE EPISODES SUPPORT THE PODCAST π₯° ...
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You can buy Lanmaoa asiatica at a food market in Yunnan. Cook it thoroughly and it's just a bolete. Undercook it, and roughly 12 to 24 hours later you may spend the next three to seven days seeing hyper-realistic miniature people moving through your environment β documented across three independent cultures, mechanism completely unknown. Ethnobotanist Colin Domnauer (Dentinger Lab, Natural History Museum of Utah) is one of the few people actively trying to understand why. Colin and I get into what's actually documented about Lanmaoa asiatica β the three independent cultural accounts, the...
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Psychedelics don't just "alter" your state β they can dissolve the self, surface the unconscious, and open the door to mystical experience. Your host, James, shares what's actually happening. ... This is a clip from 'Psychedelics in Research & Practice | James W. Jesso ~ ATTMind Podcast 200" FULL INTERVIEW SUPPORT THE PODCAST π₯° Other options Support Once on PayPal: Toss Me a Tip on Ko-Fi: Buy Some Merchandise: More Options: Connect with Me Bluesky: LinkedIn: X: Newsletter: Substack: Telegram...
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This episode of the podcast is going to explore an intersection of psychotherapy and spirituality. Specifically, we are going to be exploring the intersection between Internal Family Systems, spiritual healing, and the work of 16c Christian philosopher and mystic Emanuel Swedenborg. Our guests are Bob Falconer, Chelsea Odhner, and Jonathan Rose. What You'll Learn About: π Introduction to Internal Family Systems (IFS) and the teachings of Emmanuel Swedenborg π The intersection and synthesis between these two systems of thinking π§ Fundamental metaphysical concepts: the nature of the...
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This episode is going to be a deep dive into extended-state dimethyltryptamine, otherwise known as DMTx. Our guests for this episode are Hayley Mann and Kevin Thorbahn, who run one of only a handful of places in the world where DMTx is available outside of clinical trials. They are on the show to talk about: 𧬠What DMTx is and how it works π What people experience during a DMTx session π Why people choose to undergo the experience β±οΈ How long people stay in for π‘ What people get out of the experience π₯ Where DMTx may fit in the growing psychedelic medical and personal use...
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Research Psychologist Jessica Corneille discusses the complex integration process that follows spontaneous spiritual experiencesβparticularly the disorientation, vocational tension, and identity shifts that can arise when a transformed worldview no longer aligns with oneβs work or social context. The conversation explores the emergence of spiritual crisis during integration, the importance of non-hierarchical support spaces, and how connection, community, and spiritual literature (including reflections on Alan Watts) can help individuals rebuild a coherent sense of self and purpose after...
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Thomas Hatsis joins us for episode 205 to discuss his new book Psychedelic Injustice: How Identity Politics Poisons the Psychedelic Renaissance. Together we discuss some pretty divisive topics: the distinction between social justice and critical social justice, how certain narratives are being imposed on the psychedelic movement, implicit bias research, decolonization rhetoric, the drug war's actual causes, and contested claims about psychedelic history. This one might get spicy for you. Enjoy responsibly. This episode was nearly taken down RELEVANT LINKS π π GET THE BOOK: π€...
info_outlineWe are doing something special in celebreation of episode 200. Instead of an interview, I recorded a straight-talk lecture on psychedelics.
Together, we are going to explore what psychedelics are; why they are so interesting to research; and the chemistry, pharmacology, phenomenology, history, and current research on Psilocybin, DMT, MDMA, Ketamine, and Ibogaine.
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FULL TOPICS BREAKDOWN BELOW
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Episode Breakdown
- (00:00) Opening
- (00:47) Introduction
- (08:07) Lecture Begins
- (13:30) What is a psychedelic
- (27:53) What makes psychedelics so interesting to research
- (37:18) Splitters vs Lumpers
- (39:01) Psilocybin (magic mushrooms)
- (59:50) DMT
- (1:07:08) Ayahuasca
- (1:13:21) MDMA
- (1:39:51) Patreon Thanks
- (1:44:24) Ketamine
- (2:04:58) Ibogaine (Iboga)
- (2:36:27) Outro