Psychedelics in Research & Practice | James W. Jesso ~ ATTMind 200
Release Date: 09/19/2025
Adventures Through The Mind
This episode is going to be a deep dive into extended-state dimethyltryptamine, otherwise known as DMTx. Our guests for this episode are Hayley Mann and Kevin Thorbahn, who run one of only a handful of places in the world where DMTx is available outside of clinical trials. They are on the show to talk about: ๐งฌ What DMTx is and how it works ๐ What people experience during a DMTx session ๐ Why people choose to undergo the experience โฑ๏ธ How long people stay in for ๐ก What people get out of the experience ๐ฅ Where DMTx may fit in the growing psychedelic medical and personal use...
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Research Psychologist Jessica Corneille discusses the complex integration process that follows spontaneous spiritual experiencesโparticularly the disorientation, vocational tension, and identity shifts that can arise when a transformed worldview no longer aligns with oneโs work or social context. The conversation explores the emergence of spiritual crisis during integration, the importance of non-hierarchical support spaces, and how connection, community, and spiritual literature (including reflections on Alan Watts) can help individuals rebuild a coherent sense of self and purpose after...
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Thomas Hatsis joins us for episode 205 to discuss his new book Psychedelic Injustice: How Identity Politics Poisons the Psychedelic Renaissance. Together we discuss some pretty divisive topics: the distinction between social justice and critical social justice, how certain narratives are being imposed on the psychedelic movement, implicit bias research, decolonization rhetoric, the drug war's actual causes, and contested claims about psychedelic history. This one might get spicy for you. Enjoy responsibly. This episode was nearly taken down RELEVANT LINKS ๐ ๐ GET THE BOOK: ๐ค...
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Dr. David Katz is a board-certified specialist in Preventive Medicine/Public Health. He is on the show to talk about the paper is was author on, titled, โA multiscale inflammatory map: linking individual stress to societal dysfunctionโ. We talk about what stress and inflammation are, and the dynamics between them; how and why inflammation becomes chronic; how inflammation compromises perception and behaviour; how it can spread through a population like a contagion; how these spreading patterns of inflammation degrade our social systems, institutions, and leadership; how social media...
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Psychedelic historian Tom Hatsis outlines why the "mushroom Santa hypothesis" is not based in any historical fact and why. Happy Holidays! ... This is a clip from 'Debunking The Mushroom Santa Hypothesis | Tom Hatsis ~ ATTMind Podcast 89" FULL INTERVIEW SUPPORT THE PODCAST ๐ฅฐ Other options Support Once on PayPal: Toss Me a Tip on Ko-Fi: Buy Some Merchandise: More Options: Connect with Me Bluesky: LinkedIn: X: Newsletter: Substack: Telegram Channel:
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Charley Wininger returns to Adventures Through The Mind to discuss How To Host An MDMA Group Roll Our discussions starts with a quick general overview of MDMA before shifting into a thorough exploration of group rollsโwhat they are, what they can offer us individually and collectively, who to invite, who not to invite, where to do it, what to include, what to exclude, safety protocols, and just a whole number of things. Enjoy! ๐ โ๏ธ ๐ BUY CHARLEY'S BOOK: FULL TOPICS BREAKDOWN BELOW ... SUPPORT THE PODCAST ๐ฅฐ ๐ง ๐ง ๐ ...
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Dr. Mikael Palner discusses how psilocybin microdosing alters synaptic plasticity in rats and how these brain changes align with shifts in stress resiliancy and compulsive behaviors. He then discusses how these data line up with emerging reports on low-dose psilocybin as helpful in cases of OCD, and hypothesizes a plausible biological basis. ... This is a clip from 'Microdosing Psilocybin; Effects on Stress Resiliency and Compulsive Behaviours | Dr. Mikael Palner ~ ATTMind Podcast 194" FULL INTERVIEW SUPPORT THE PODCAST ๐ฅฐ Other options Toss me a tip on PayPal: Buy some...
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Author and psychotherapist Marc Aixalร is on the show to talk to us about psychedelic integration. What You'll Learn About: ๐ก -- What psychedelic integration actually is, what it offers, and why it matters โฐ -- When and how to apply different integration practices over time ๐ค -- Common mistakes made in both practice and understanding of integration ๐งฉ -- Approaches to working with derealization, depersonalization, and difficult or traumatic psychedelic experiences ๐ -- How to integrate experiences of the transcendental and transpersonal ๐ฅ -- Key insights for...
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East Forest (Krishna-Trevor Oswalt) is a musician and documentary filmmaker exploring the intersection of music and psychedelic consciousness. He joins us on this episode of Adventures Through The Mind to talk about what music really is and why it matters so much for our psychedelic journeys. Enjoy ๐ ... ๐ ๐ ๐ East Forest 2025/26 tour and album links Tour: FULL TOPICS BREAKDOWN BELOW ... SUPPORT THE PODCAST ๐ฅฐ ๐ง ๐ง ๐ *** Huge thanks to my patrons on Patreon! In particular, my $23+ patrons; Andreas D, Alex F, and...
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Ed Prideaux discusses the the phenomenon of "Psychedelic Flashbacks" and how they relate to Hallucinogen Perception Persisting Disorder, also known as as HPPD. ... This is a clip from 'Hallucinogen Perception Persisting Disorder (HPPD) | Ed Prideaux ~ ATTMind Podcast 152 FULL INTERVIEW SUPPORT THE PODCAST ๐ฅฐ Other options Toss me a tip on PayPal: Buy some merchandise: More Options: โท Sponsor: Use the promo code JESSO for 15% off your First order Connect with Me Bluesky: Instagram: Newsletter: Substack: Telegram Channel:
info_outlineWe are doing something special in celebreation of episode 200. Instead of an interview, I recorded a straight-talk lecture on psychedelics.
Together, we are going to explore what psychedelics are; why they are so interesting to research; and the chemistry, pharmacology, phenomenology, history, and current research on Psilocybin, DMT, MDMA, Ketamine, and Ibogaine.
๐ Website and Episode Show Notes
๐ BUY MY BOOKS: DECOMPOSING THE SHADOW: LESSONS FROM THE PSILOCYBIN MUSHROOM | THE TRUE LIGHT OF DARKNESS
FULL TOPICS BREAKDOWN BELOW
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SUPPORT THE PODCAST
๐ฅฐ Support ATTMind and join the community on Patreon
๐ง Sub and Review on Apple Podcasts
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*** Huge thanks to my patrons on Patreon!
In particular, my $23+ patrons; Andreas D, Alex F, and Eliz C
Other options
- Toss me a tip on PayPal: https://www.paypal.com/biz/fund?id=383635S3BKJVS
- Buy some merchandise: https://www.jameswjesso.com/shop/
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Episode Breakdown
- (00:00) Opening
- (00:47) Introduction
- (08:07) Lecture Begins
- (13:30) What is a psychedelic
- (27:53) What makes psychedelics so interesting to research
- (37:18) Splitters vs Lumpers
- (39:01) Psilocybin (magic mushrooms)
- (59:50) DMT
- (1:07:08) Ayahuasca
- (1:13:21) MDMA
- (1:39:51) Patreon Thanks
- (1:44:24) Ketamine
- (2:04:58) Ibogaine (Iboga)
- (2:36:27) Outro