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534: Why You're Still Deficient After Taking All the Right Supplements (The Absorption Problem Gets Worse in Midlife) with Lindsey Burwell

Midlife Conversations with Natalie Jill: Fat Loss, Hormones & Health for Women Over 40

Release Date: 06/26/2026

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Tired of choking down pills and wondering if any of it is showing up? Transdermal could be the answer. The Patch Method bypasses our digestion and liver completely. Super easy, just slap it on. Code NATALIEJILL for 20% off at http://thepatchmethod.com  PLUS… DM "NatalieJill" to @the.patchmethod on Instagram and the first 50 people will receive a free patch kit of their choice plus four free samples.

What if the drawer full of supplements you have been faithfully taking every morning is actually making your liver work harder without making you feel any better?

If you have ever walked out of a functional medicine or naturopathic appointment with a list of twelve supplements, spent hundreds of dollars filling that order, and then showed up to your next appointment still deficient in the very things you were supplementing, you are not alone. And according to Lindsey Burwell, founder of The Patch Method, you are also not the problem.

Lindsey was one of my most talked-about guests ever, and she is back for part two because your questions did not stop after our first conversation. Today we go even deeper into why swallowing supplements is often a losing game for midlife women, and what transdermal delivery actually does differently at a physiological level.

We cover the science of first-pass metabolism and why your liver, already under enormous strain from modern life, is simply not prioritizing breaking down your vitamin C. We talk about what "pill fatigue" really is and why it is only getting louder. And we get into the specific patches Lindsey has developed, including the detox patch, the cortisol fix, the menopause patch, and the one I have been waiting to try: the GHKCU copper peptide glow patch, which has serious research behind it for skin regeneration, hair growth, and cellular repair.

I also finally get Lindsey to walk me through why the injectable version of that copper peptide causes that intense, all-day throbbing sensation, and why the transdermal version sidesteps that entirely. Spoiler: it comes back to dose.

If you have MTHFR or a slow COMT and have had bad reactions to methylated B vitamins, Lindsey explains exactly why the patch form does not cause that same stimulant response. We also dig into who should and should not be using these patches, how to stack them, and why you do not have to give up the supplements that are already working for you.

This is one of those episodes that makes you want to go audit your entire supplement cabinet.

 

WE GO DEEP ON: 

  • Why your liver may be working 3,000x harder than it used to

  • Why supplements are dosed at 10,000% of your daily need

  • What actually happens to a pill before it reaches your bloodstream

  • Why MTHFR carriers react badly to B vitamins in pill form, not patches

  • The detox patch protocol for clearing excess estrogen on HRT

  • Why the GHKCU injectable causes all-day throbbing, and the patch doesn't

  • What 90 days of copper peptide use can do for hair and skin

  • The adaptogen blend behind some of the best sleep scores Lindsey has seen

  • Whether you can stack multiple patches at once

  • Who should never use these patches

 

Catch the full episode on YOUTUBE HERE: https://bit.ly/MidlifeConversationsYouTube

 

Learn More About Lindsey Burwell

Instagram ➜ http://www.instagram.com/the.patchmethod 

Website ➜ http://thepatchmethod.com use code NATALIEJILL to save 

 

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Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen. 

Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.