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Science News: Biogen and the FDA

Mad in America: Science News

Release Date: 08/31/2021

Science News: No Link Between Serotonin and Depression - What Does That Mean for Antidepressants? show art Science News: No Link Between Serotonin and Depression - What Does That Mean for Antidepressants?

Mad in America: Science News

In this 30-minute podcast, Peter Simons reports on the latest scientific articles in psychiatry. The goal is to provide more detail than is usually found in conventional research news and to help listeners understand how to interpret the findings. This month, Peter Simons covers in detail a new systematic review that debunks the widely popularized myth of low serotonin in depression, the “chemical imbalance theory.” He then follows up with a study that found less than 25% of people respond to depression treatment in real life, and a study that found that screening for depression in...

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Science News: Pharma Corruption, Dangers of Antidepressants, And More show art Science News: Pharma Corruption, Dangers of Antidepressants, And More

Mad in America: Science News

In this 30-minute podcast, Peter Simons reports on the latest scientific articles in psychiatry. The goal is to provide more detail than is usually found in conventional research news and to help listeners understand how to interpret the findings. Articles covered in this podcast include: How the is of ; How ; How pharma company on its Alzheimer’s research and outcome data; How ; Researchers document how ; A study finding that ; A study on if taken during pregnancy; A paper explaining ; A paper on the ; A study finding that ; and A paper by Joanna Moncrieff on the ties between .

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Science News: Psychology: Flawed as a Science and as Evidence-Based Medicine show art Science News: Psychology: Flawed as a Science and as Evidence-Based Medicine

Mad in America: Science News

In this 30-minute podcast, Peter Simons reports on the latest scientific articles in psychiatry. The goal is to provide more detail than is usually found in conventional research news and to help listeners understand how to interpret the findings. Articles covered in this podcast include: Researchers write that ; Researchers suggest that than reliable science; Psychiatrists of any medical specialty; A promotes non-coercive mental health treatment; Black patients in the US were to be described negatively in electronic health records; A peer-supported Open Dialogue program shows ;...

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Science News: Brain Imaging Results False; Unpublished and Missing Trials; Why Meditation May Not Work for You show art Science News: Brain Imaging Results False; Unpublished and Missing Trials; Why Meditation May Not Work for You

Mad in America: Science News

Peter Simons covers a study in Nature finding that the positive results of psychiatry’s brain imaging studies are false; a study demonstrating that more than half of negative antidepressant trials remain unpublished or are misleadingly “spun” as positive; an article that may explain why some people don’t find meditation to be helpful; and more!

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Science News: How Effective Are Therapy and Medication, and What Do They Treat? show art Science News: How Effective Are Therapy and Medication, and What Do They Treat?

Mad in America: Science News

Peter Simons covers a study that found both therapy and medication to have very limited effectiveness; an article suggesting that general practitioners need to prescribe fewer antidepressants; a study that concluded no brain imaging test has been able to identify a meaningful brain difference in depression; and more!

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Science News: Lithium, Antidepressants, Esketamine—All No Better Than Placebo? show art Science News: Lithium, Antidepressants, Esketamine—All No Better Than Placebo?

Mad in America: Science News

Peter Simons covers a clinical trial that found lithium ineffective at preventing suicide attempts, an essay by Allen Frances on the overdiagnosis of depression and overprescription of antidepressants, a review of the ineffectiveness and dangers of antidepressants, and an analysis that revealed that esketamine failed five of its six clinical trials.  

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Science News: Unscientific Diagnoses Medicalize Normal Human Experiences show art Science News: Unscientific Diagnoses Medicalize Normal Human Experiences

Mad in America: Science News

Peter Simons covers articles about the validity of psychiatric diagnoses, the medicalization of normal human experiences like grief, and how the pharmaceutical industry co-opts feminist messaging to gain approval for ineffective drugs.

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Science News: Antidepressant Research - Placebos and Withdrawal show art Science News: Antidepressant Research - Placebos and Withdrawal

Mad in America: Science News

This week, Peter Simons covers a study about the controversial practice of placebo run-in periods in antidepressant studies, a study about withdrawal symptoms being mistaken for relapse, and a book chapter that addresses stigma and discrimination.

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Science News: Reducing Stigma/Psychotherapy for Depression in Children show art Science News: Reducing Stigma/Psychotherapy for Depression in Children

Mad in America: Science News

This week, Peter Simons covers studies examining whether mental health literacy and essentialist thinking are associated with stigma against those with mental health problems. He also covers a study finding that psychotherapy is ineffective for the majority of children with depression.

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Science News: Antipsychotics and Cancer, Screening for Depression, and Alzheimer's Drug Controversy show art Science News: Antipsychotics and Cancer, Screening for Depression, and Alzheimer's Drug Controversy

Mad in America: Science News

This week, Peter Simons covers a study that found prolactin-increasing antipsychotics associated with increased breast cancer risk, an analysis that found no convincing evidence that screening for depression improves outcomes, and the continuing controversy around the FDA's approval of Biogen's failed Alzheimer's drug aducanumab.

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More Episodes
This week, Peter Simons covers a BMJ investigation that found the FDA's "accelerated approval" process has left ineffective drugs on the market, some for more than 20 years, without follow-up studies to demonstrate efficacy. He also covers further developments in the FDA and Biogen controversy around Alzheimer's drug aducanumab (Aduhelm).