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Does PACAP 38 Work Differently Than CGRP? show art Does PACAP 38 Work Differently Than CGRP?

Migraine Minute News Update

New research shows CGRP monoclonal antibody treatment may not prevent migraine attacks triggered by the neuropeptide PACAP-38. This study suggests PACAP-38 may act through a different pathway and could become a future preventive option for people who don’t respond to CGRP-based treatments. Molly O’Brien explains in this Migraine Minute News Update.  Read More: Images courtesy: Springer Nature. The Journal of Headache and Pain. doi: 10.1186/s10194-025-02022-2 Creative Commons license: Script: Does PACAP 38 Work Differently Than CGRP? A new study published in the Journal of Headache...

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Can Erenumab Treat Medication Overuse Headache? show art Can Erenumab Treat Medication Overuse Headache?

Migraine Minute News Update

A study published in JAMA Neurology shows that monthly erenumab injections may help treat medication overuse headache (MOH) in people with chronic migraine. While the 140 mg dose was effective for treating MOH, the 70 mg dose did not show a meaningful difference compared to placebo. Molly O’Brien explains in this Migraine Minute News Update. Read More: Image Courtesy: JAMA Neurology doi:10.1001/jamaneurol.2024.3043 Transcript: A study published in JAMA Neurology looked at the safety and efficacy of a CGRP monoclonal antibody for treating Medication Overuse Headache in people with...

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Predicting if a Preventive Migraine Treatment Will Work show art Predicting if a Preventive Migraine Treatment Will Work

Migraine Minute News Update

Most people with migraine go through trial and error to find a preventive treatment that works. But researchers at the Mayo Clinic may have found a way to change that. Using AI, they developed a tool to predict how someone might respond to certain migraine medications—particularly CGRP monoclonal antibodies. Molly O’Brien has more in this Migraine Minute News Update. Read More:    

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Can This Preventive Drug Bring Immediate Migraine Relief? show art Can This Preventive Drug Bring Immediate Migraine Relief?

Migraine Minute News Update

Rapid relief from a preventive migraine treatment? A study published in Neurology shows that one oral gepant medication may start working right away to prevent migraine attacks. Molly O’Brien fills you in, in this Migraine Minute News Update. Read more:

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FDA Approves Axsome’s New Migraine Drug Symbravo® show art FDA Approves Axsome’s New Migraine Drug Symbravo®

Migraine Minute News Update

The FDA has approved a new drug for the acute treatment of migraine with or without aura in adults. Molly O’Brien has the details and when it becomes available in this Migraine Minute News update.    Learn More:

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Can CGRP Blocking Drugs Help Endometriosis? show art Can CGRP Blocking Drugs Help Endometriosis?

Migraine Minute News Update

Researchers in Boston found that CGRP-blocking drugs commonly used for migraine may help with endometriosis pain and lesion size. Molly O’Brien has the details in this Migraine Minute news update recognizing Endometriosis Awareness Month.  Read More: https://bit.ly/4jp0cG2 AMD Comorbidities Library: https://bit.ly/3CIrLtd

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Cluster Headache Often Coexists with Fibromyalgia & Migraine show art Cluster Headache Often Coexists with Fibromyalgia & Migraine

Migraine Minute News Update

Cluster Headache Awareness Day is March 21st. In this Migraine Minute News Update Molly O’Brien explains findings from a study that found cluster headache, fibromyalgia, and migraine are frequently comorbid conditions. Learn More: 

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Ubrogepant Reduced Migraine-Related Limitations When Taken During the Prodrome Phase show art Ubrogepant Reduced Migraine-Related Limitations When Taken During the Prodrome Phase

Migraine Minute News Update

According to a study published in Neurology, when compared to placebo, this gepant led to significantly greater ability to function normally and a greater reduction in activity limitation when taken during the prodrome phase of an attack. Molly O’Brien has the details in this Migraine Minute News Update.  Read More: https://bit.ly/3BY2J9d

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FDA Clears Nerivio Device for Children 8+ show art FDA Clears Nerivio Device for Children 8+

Migraine Minute News Update

Kids age 8+ now have access to a non-drug migraine treatment option. In this Migraine Minute News Update, Molly O’Brien explains the FDA clearance of Theranica’s Nerivio device for acute and preventive migraine treatment in kids.   Read more:

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MERTK as a Potential Novel Target for Cluster Headache show art MERTK as a Potential Novel Target for Cluster Headache

Migraine Minute News Update

Researchers have identified elevated levels of the gene MERTK, (which is linked to cluster headaches) and its ligand Gal-3, in the nerve tissues of rats and in blood samples of people with cluster headache. In this Migraine Minute News Update Molly O’Brien breaks down what it means for people living with Cluster. Read More:

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Rapid relief from a preventive migraine treatment? A study published in Neurology shows that one oral gepant medication may start working right away to prevent migraine attacks. Molly O’Brien fills you in, in this Migraine Minute News Update.

Read more: https://bit.ly/3Wvb1fU