ANA Investigates Thrombectomy in Patients with Large Ischemic Strokes
Release Date: 03/21/2023
ANA Investigates the Making of Women Leaders in Academic Neurology
ANA Investigates
Women are reshaping leadership in academic neurology, representing a growing share of the field yet remaining underrepresented in its most senior roles. In this episode of ANA Investigates, we had the privilege of speaking with two former women presidents of the American Neurological Association. Dr. Elizabeth Ross is a professor of neurology and neuroscience and director of the Center for Neurogenetics at Weill Cornell Medicine. Dr. Frances E. Jensen is professor and chair of the Department of Neurology and co-director of the Translational Neuroscience Program at the University of...
info_outline
ANA investigates Mechanical Thrombectomy for Medium Vessel Occlusions
ANA Investigates
In this episode, we are discussing one of the most rapidly evolving areas in acute stroke care, mechanical thrombectomy for medium vessel occlusions, or MEVO. While thrombectomy is well established for large vessel occlusions, whether patients with smaller, more distal occlusions benefit has remained an important unanswered question. In the recent years, several landmark trials have evaluated endovascular treatment for MEVO with differing results, some suggesting benefits while others suggesting no benefit. Together, these studies have shifted the conversation from whether thrombectomy...
info_outline
ANA Investigates Pediatric Epilepsy Surgeries
ANA Investigates
In this episode, we'll discuss pediatric epilepsy surgery. Pediatric epilepsy surgery has undergone a remarkable evolution, moving from a treatment of last resort to a critical option for children with drug-resistant epilepsies. Yet major barriers remain, including delayed referrals, fear of brain surgery, and uncertainty around risks and benefits. At the same time, advances in imaging, genetics, and neuromodulation are shaping the utility of epilepsy surgery. For an update in pediatric epilepsy surgery, we spoke with Dr. Ahsan Moosa Naduvil Valappil, a pediatric epileptologist and an...
info_outline
ANA investigates ALS Research and Healey ALS MyMatch
ANA Investigates
In this episode, we will focus on the latest in the research on ALS. ALS remains a devastating disease, but the field is now at an inflection point with a growing pipeline of precision therapies, trial-ready sites, and a new generation of clinician scientists - yet barriers persist. There is disease heterogeneity, limited trial access for patients, and rising development costs. For an update on ALS clinical trials and the Healey ALS MyMatch program, a centralized platform that matches participants to trials, we spoke with Dr. Suma Babu. Dr. Suma Babu is an associate professor of neurology...
info_outline
ANA investigates the Evolution of the ANA Podcast
ANA Investigates
ANA Investigates is the official podcast of the American Neurological Association, featuring conversations that highlight the latest discoveries, controversies, and trends in academic neurology. After the successful release of over 80 podcast episodes, In today’s episode, we’ll explore the creation and evolution of the ANA Investigates podcast since its launch in September 2019. We have the privilege of hosting four legends who were instrumental in bringing this podcast to life. First, Dr. Adeline Goss, Assistant Professor at Highland Hospital in Oakland, California, whose background as a...
info_outline
ANA Investigates Debates in Idiopathic Normal Pressure Hydrocephalus
ANA Investigates
The diagnosis and management of idiopathic normal pressure hydrocephalus (NPH) is evolving. However, skepticism about this diagnosis persists among neurologists based upon lack of disease specific pathology, overlap with other neurodegenerative processes, and a lack of uniform diagnostic criteria. Also, prior reports of minimal or transient improvement after treatment with an invasive procedure and lack of high-quality studies has concerned some neurologists. We are joined by 2 experts in the field of movement disorders and CSF flow – Dr. Alberto Espay and Dr. Michael Williams – to discuss...
info_outline
ANA Investigates Adaptive DBS
ANA Investigates
Last year, the FDA approved adaptive deep brain stimulation for the treatment of people with Parkinson's disease. This is a major step forward in neurology. It allows personalized therapy by adjusting deep brain stimulation settings in real-time based on an individual's brain signals. Our guest on this episode is Dr. Helen Bronte-Stewart, the John E. Cahill Family Professor of Neurology and Director of the Human Motor Control and Neuromodulation Lab at Stanford University. Dr. Bronte-Stewart was interviewed by Dr. Karlo Lizarraga, Associate Professor of Neurology and Director of the Motor...
info_outline
ANA investigates NORSE and FIRES
ANA Investigates
In this episode, we'll focus on new onset refractory status epilepticus or NORSE, and its closely related presentation, febrile and infection related epilepsy syndrome, known as FIRES. NORSE and FIRES are clinical presentations where the evidence is limited, stakes are high, and treatment often has to begin before the diagnosis is clear. They also raise broader questions about how neurology can respond to rare but catastrophic illness, including how patients, families and researchers can work together to move the field forward. For an update on NORSE and FIRES, we spoke with Dr. Howard...
info_outline
ANA Investigates Emerging Strategies to Enhance Stroke Recovery
ANA Investigates
In this episode, we'll explore emerging strategies to enhance recovery after stroke. Stroke rehabilitation has long relied on physical, occupational, and speech therapy, but advances in neuroscience are opening new opportunities to directly modulate brain networks, promote plasticity, and hopefully help patients regain function. Dr. Sean Dukelow's work focuses on neurorehabilitation and the mechanisms of recovery after stroke. He's a professor and head of Physical Medicine and Rehabilitation in the Department of Clinical Neurosciences at the University of Calgary. Dr. Dukelow was interviewed...
info_outline
ANA Investigates Stroke and its Future: Reflections of a Legend
ANA Investigates
Today, we’ll talk with one of the true giants of stroke neurology - Dr. Louis Caplan, Professor of Neurology at Harvard Medical School and Senior Neurologist at Beth Israel Deaconess Medical Center. For decades, Dr. Caplan has shaped how we think about stroke. He’s authored an enormous body of work -- landmark papers, books, and clinical descriptions that have changed how neurologists around the world recognize and classify strokes. But today, rather than revisiting the past, we’ll ask how he sees the future - of stroke, clinical reasoning in an era of AI, and of medicine itself. Dr....
info_outlineAmong several highlights of the recent International Stroke Conference was new evidence supporting endovascular thrombectomy for patients with so-called “large core” ischemic strokes. In current practice, thrombectomy is considered for patients with occlusions of the internal carotid or middle cerebral artery who are less than 24 hours since the last known well and have a small “core” of ischemia on non-contrast head CT or CT or MR perfusion imaging -- in other words, there’s radiographic evidence that only a small core of the brain has suffered permanent injury and a larger penumbra of tissue can be saved. SELECT-2 is a multicenter randomized controlled trial that examined whether patients with LARGE cores of ischemic tissue could ALSO benefit from thrombectomy. On our show today we have SELECT-2 principal investigator Dr. AM-rou sou-RAJ, who is also Professor of Neurology at Case Western Reserve University School of Medicine. He was interviewed by Dr. Michelle Johansen, vascular neurologist at Johns Hopkins University, about what the study results might mean for stroke care -- and stroke imaging -- going forward. Series 4, Episode 6. Featuring:
- Guest: Amrou Sarraj, MD FAHA, Professor of Neurology, Case Western Reserve University School of Medicine, George M. Humphrey II Endowed Chair, University Hospitals Neurological Institute, Director, Comprehensive Stroke Center and Stroke Systems, University Hospitals
- Interviewer: Dr. Michelle Johansen, Johns Hopkins Medicine
- Producer: Dr. Joseph Carrera, University of Michigan
Disclosures: Dr. Sarraj discloses the following relationships: SELECT2 principal investigator - funded by Stryker Neurovascular with research grant to University Hospitals Cleveland Medical Center and UT McGovern Medical School SELECT principal investigator - funded by Stryker Neurovascular with research grant to UT McGovern Medical School Member, Speaker bureau and advisory board - Stryker Neurovascular Provided advisory services to AstraZeneca, Genentech and Lumosa Theraputics