ANA Investigates Thrombectomy in Patients with Large Ischemic Strokes
Release Date: 03/21/2023
ANA Investigates the Glymphatic System & Neurodegenerative Diseases
ANA Investigates
Until recently, the Glymphatic System was a neglected corner of neuroscience. Now it’s increasingly clear that the brain’s system for the flow of fluid, nutrients, and waste plays an important role in sleep and brain disease. With glymphatics in the spotlight, researchers are coming up with innovative ways to study this slow, constant flow of cerebrospinal fluid throughout the brain. Dr. Daniel Claassen is a Professor of Neurology and Chief of the Behavioral and Cognitive Neurology Division at Vanderbilt University, who researches the glymphatic system in humans. He’ll talk about new...
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**Bonus Episode** ANA Investigates ANA2024
ANA Investigates
Just last week, we wrapped up another exciting annual meeting of the American Neurological Association, ANA2024. Right before we packed up to head home, the President of the American Neurological Association, Dr. Betsy Ross, sat down with Dr. Allison Willis, the 2024 chair of the ANA’s Annual Meeting Programming Committee, to reflect on some of the highlights of this year's meeting. Series 5, Episode 12 Featuring: Guest: Dr. Allison Willis, the 2024 chair of the ANA’s Annual Meeting Programming Committee Interviewer: Dr. Betsy Ross, President of the American Neurological Association -...
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ANA Investigates Psychedelics & Unlocking Critical Periods
ANA Investigates
Listen as Dr. Adeline Goss, Associate Chief of Neurology at Highland Hospital, discusses the groundbreaking potential of psychedelics in neurology with Dr. Steve Zeiler, a Vascular Neurologist and Associate Professor at Johns Hopkins, and Dr. Ghul Dölen, a Professor of Psychology and Neuroscience at UC Berkeley. The conversation explores the newfound excitement surrounding psychedelics like MDMA, LSD, and psilocybin for treating mood disorders like depression and neurologic conditions such as stroke recovery. The experts also delve into research showing psychedelics' ability to reopen...
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ANA Investigates AI in Academia
ANA Investigates
AI is everywhere, whether you are a fan of it or not. This month, join us for a deep dive into the AI revolution with our guest Dr. Ethan Mollick, professor at The Wharton School at the University of Pennsylvania and author of the New York Times bestseller, "Co-Intelligence." Discover how this AI revolution stands apart from past technological advancements and how it is transforming academic research. Ethan was interviewed for this episode by Dr. Zach London, an Associate Professor at the University of Michigan Medical School.
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ANA Investigates Minimally Invasive Neurosurgeries for Spontaneous Intracerebral Hemorrhage
ANA Investigates
There has been tremendous progress in recent decades in the management of ischemic strokes. Meanwhile, hemorrhagic strokes have stubbornly resisted this progress. Interventions for these types of strokes have failed again and again to show a benefit over standard medical management, until this year. The recently published ENRICH trial is the first to show that minimally invasive neurosurgery may improve functional outcomes for patients with hemorrhagic stroke. Study lead author, Dr. Gustavo Pradilla joins us today to talk about the differences between ENRICH and previous negative trials, and...
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ANA Investigates MMA Embolization
ANA Investigates
2024 has been a year of exciting trials on minimally invasive techniques in intracranial hemorrhage. This month we're focusing on Chronic Subdural Hematoma, where a minimally invasive strategy called Middle Meningeal Artery (MMA) Embolization is offering expanded treatment options for select patients. Dr. Chris Kellner is a cerebrovascular neurosurgeon and associate professor of neurosurgery at Mount Sinai. He'll talk about the promise of MMA embolization with Dr. Sarah Nelson, neurointensivist and neurohospitalist at Tufts Medical Center. We'll have more on these trials on the podcast in our...
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ANA Investigates Neuroprognostication After Cardiac Arrest: Nihilism vs. Over Optimism
ANA Investigates
Football fans may remember in January 2023 when Damar Hamlin, a player for the Buffalo Bills, suffered a cardiac arrest and collapsed on the field during a game on live television. He had a remarkable neurologic recovery, prompting us to focus our podcast that month on the need to avoid nihilism when we prognosticate after cardiac arrest. But what is the right balance between pessimism and optimism? Today, we'll hear from Dr. Karen Hirsch, neuro intensivist and associate professor of neurology at Stanford, about finding the Goldilocks zone in neuro prognostication after cardiac arrest. Dr....
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ANA Investigates Advanced Therapies for Glioblastoma
ANA Investigates
Glioblastoma is the most common malignant brain tumor and one of the most aggressive solid tumors. Much progress has been made in the understanding and classification of gliomas, but progress in terms of prolonging survival has been limited. Several recent investigational therapies are bringing new hope. Our guest today is Dr. Eric Wong from Brown University. He is an international expert on advanced treatments for glioblastoma and a Professor of Medicine, Radiation Oncology, Neurosurgery, and Neurology at Brown University. He was interviewed by Dr. Christoph Stretz, a Vascular and Critical...
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ANA Investigates Updated Brain Death Determination Guidelines
ANA Investigates
Brain death is one of the most controversial and ethically complex topics in neurology, but it's a regular part of our clinical practice. Late last year, a new set of guidelines was published that address some of the thorniest technical and ethical issues in the clinical determination of brain death. For this discussion, we are joined by Dr. Ariane Lewis, a professor in the departments of Neurology and Neurosurgery, as well as the director of the Division of Neurocritical Care at NYU Langone Medical Center, and Dr. Matthew Kirschen, an assistant professor of Anesthesiology and Critical Care...
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ANA Investigates Auto-Antibodies for Small Fiber Neuropathy
ANA Investigates
Small fiber neuropathy is one of those conditions in neurology that can feel frustratingly intangible. Even for patients with severe neuropathic pain and autonomic symptoms, in about half of cases, the usual lab testing doesn't reveal a cause. There's increasing evidence that autoimmunity may be a factor in some of these cases of idiopathic small fiber neuropathy, but how to test and who to treat with immunosuppression is less clear. Our guest today, Anne Louise Oaklander, is an Associate Professor of Neurology at Massachusetts General Hospital and an Assistant in Neuropathology. She's known...
info_outlineAmong several highlights of the recent International Stroke Conference was new evidence supporting endovascular thrombectomy for patients with so-called “large core” ischemic strokes. In current practice, thrombectomy is considered for patients with occlusions of the internal carotid or middle cerebral artery who are less than 24 hours since the last known well and have a small “core” of ischemia on non-contrast head CT or CT or MR perfusion imaging -- in other words, there’s radiographic evidence that only a small core of the brain has suffered permanent injury and a larger penumbra of tissue can be saved. SELECT-2 is a multicenter randomized controlled trial that examined whether patients with LARGE cores of ischemic tissue could ALSO benefit from thrombectomy. On our show today we have SELECT-2 principal investigator Dr. AM-rou sou-RAJ, who is also Professor of Neurology at Case Western Reserve University School of Medicine. He was interviewed by Dr. Michelle Johansen, vascular neurologist at Johns Hopkins University, about what the study results might mean for stroke care -- and stroke imaging -- going forward. Series 4, Episode 6. Featuring:
- Guest: Amrou Sarraj, MD FAHA, Professor of Neurology, Case Western Reserve University School of Medicine, George M. Humphrey II Endowed Chair, University Hospitals Neurological Institute, Director, Comprehensive Stroke Center and Stroke Systems, University Hospitals
- Interviewer: Dr. Michelle Johansen, Johns Hopkins Medicine
- Producer: Dr. Joseph Carrera, University of Michigan
Disclosures: Dr. Sarraj discloses the following relationships: SELECT2 principal investigator - funded by Stryker Neurovascular with research grant to University Hospitals Cleveland Medical Center and UT McGovern Medical School SELECT principal investigator - funded by Stryker Neurovascular with research grant to UT McGovern Medical School Member, Speaker bureau and advisory board - Stryker Neurovascular Provided advisory services to AstraZeneca, Genentech and Lumosa Theraputics