50k, Fake “Landmarks,” R&D Cuts & Can You Teach Common Sense?
Note to File: A Clinical Research Podcast
Welcome to another “Sticky Notes” live session of Note to File – the only clinical research podcast that’s part insightful conversation, part general nonsense. Today, we’re braving the December chill, celebrating a totally wild (and possibly confusing) 50k YouTube subscribers, and pondering whether people forget how to drive in snow every single year (spoiler: they do). We dig into the latest so-called “landmark” UK/US pharma trade deal (cue eye rolling at historic headlines), the gritty truths about public sector R&D cuts, and why axing funding and getting stingy on...
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Site Centricity, Private Equity, and Circling Back After the New Year
Note to File: A Clinical Research Podcast
This week, we dive headfirst into the holiday madness: the fine art of pretending things can wait till January, how stuffing a week’s worth of chaos into three days is our new normal, and why Thanksgiving is synonymous with “eating a regrettable amount of food” (parades optional). But don’t worry, we’re not just here for turkey talk. We rip into site centricity (is it more than branding?), the never-ending sponsor/CRO shuffle, and why clinical research still can’t figure out standardization to save its life. Private equity’s creeping fingers? NIH funding’s real impact?...
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Abbott’s $20B Buy, CRO Controversies & the Changing Face of Clinical Trials
Note to File: A Clinical Research Podcast
In this episode, we discuss the Abbott-Exact Sciences mega-acquisition, the nuanced world of CROs, challenges and opportunities in decentralized clinical trials (DCT), the explosive growth of clinical trial technology, and the real-world impact of NIH grant funding cuts. We also debate the ethics of drug availability in international trials and dig into site-centricity, innovation, and the ever-changing clinical research landscape. Also, Denali says "niche" wrong. Enjoy candid commentary, industry news, and some laughs along the way! Got feedback or want to be a guest? Reach out via LinkedIn...
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Communication Fails, (more) AI Hype & Job Market Truths
Note to File: A Clinical Research Podcast
In this episode: does AI really want your job, or is it just here for the snacks? Why does “communication” mean “good luck finding my phone number,” and can the job market get any weirder (spoiler: yes)? Brad and Denali banter about the latest “new normal,” classic tech headaches, and why public awareness still needs new batteries. You’ll get poetry, wild tangents, a little outrage, and a lot of the good stuff they never put in the company newsletter
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AI, Ads & Awkward Phone Calls with Steve Wimmer
Note to File: A Clinical Research Podcast
In this episode, Denali and Brad are joined by the ever-chill Steve Wimmer of 1nHealth for a wide-ranging, caffeine-fueled chat about everything from AI-powered patient recruitment to why running clinical trials sometimes feels like herding digital cats. We take you behind the scenes of recruitment campaigns, hash out whether AI is the solution or just a new sticker for your PowerPoint, and dig into why some sites treat digital ads like cryptic hieroglyphs. Along the way, you’ll hear hot takes on industry best practices, cold weather in Orlando (spoiler: “frigid” means below 70°F), and...
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Del Smith, Acclinate, on Representation & the Future of Clinical Research
Note to File: A Clinical Research Podcast
In this episode, Denali and Brad sit down with Del Smith, founder of Acclinate, to explore the challenges and opportunities in increasing representation in clinical research. They discuss the intersection of technology and trust, the importance of community-first approaches, the role of sites and sponsors, and offer actionable tips for sites of all sizes. Del shares his personal journey from business school dean to healthcare entrepreneur, highlighting real-world solutions for building trust and engagement in underrepresented communities.
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Walt Bogdanich, New York Times, Exposes Private Equity's Influence on IRBs
Note to File: A Clinical Research Podcast
Join us for an insightful conversation with Walt Bogdanich, three-time Pulitzer Prize-winning investigative reporter from The New York Times, as we dive deep into the world of clinical research oversight. Walt discusses his investigations into institutional review boards (IRBs), the growing influence of private equity in healthcare, transparency issues within drug trials, and the broader implications for patient safety and trust in medical innovation. Whether you’re a clinical researcher, healthcare professional, or simply interested in the intersection of medicine, business, and ethics,...
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Coordinators, Carbon, and Crime
Note to File: A Clinical Research Podcast
Denali and Brad talk about horror movies, take a deep dive into the real experiences of clinical research coordinators, and discuss whether degrees or work experience matter more. We also explore the environmental impact of clinical trials, issues of trust in research roles, and take a look at Nike's latest innovation—motorized sneakers. Join us for thoughtful discussion and some lighthearted moments.
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CRA Burnout, Global R&D Shifts, and Clinical Trial Patient Realities
Note to File: A Clinical Research Podcast
Denali and Brad tackle a wide range of critical topics in clinical research. We dive deep into the realities of CRA burnout, the shifting landscape of global clinical trials, and the implications of the U.S. focusing more on manufacturing than R&D. We also explore the challenges faced by patients navigating site errors and expanded access, discuss how technology and AI are changing the field, and reflect on the human element that underpins the industry. Along the way, you’ll hear honest perspectives, industry insights, and some lighthearted banter—including a surprise appearance from a...
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Passwords on Sticky Notes, Silos & Why EDC Still Sucks with Doug Bain
Note to File: A Clinical Research Podcast
In this episode, Denali and Brad welcome Doug Bain (ClinFlo) for a no-holds-barred chat about why site tech still stinks, EDC headaches, AI hype (and hope), platform silos, and why so many research sites are still using sticky notes for passwords. From the joys of Italian coffee breaks to Black Mirror references, Doug shares war stories, practical fixes, and predictions for where real change might finally happen. If you’ve ever wondered why clinical research tech feels 20 years behind (and how AI could actually help), don’t miss this episode!
info_outlineWhitney Stewart is the director of clinical project management at Curebase. She has served the clinical research space for more than 10 years, and holds bachelors' degrees in Molecular and Cellular biology, and Italian Studies.
In this episode we discuss evidence standards for digital therapeutics and the recent Digital Therapeutics Alliance publication “Setting the Stage for a Fit-For-Purpose DTx Evidentiary Standard”.
Whitney on LinkedIn: https://www.linkedin.com/in/whitney-stewart-b9969326/
Digital Therapeutics Alliance and Curebase release publication setting the stage for a fit-for-purpose evidence standard for digital therapeutics (DTx): https://www.curebase.com/news/digital-therapeutics-alliance-and-curebase-release-publication-setting-the-stage-for-a-fit-for-purpose-evidence-standard-for-digital-therapeutics-dtx
Learn more about our sponsor, Inato: https://go.inato.com/41YxjXY