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All’s Not Lost: A Roadmap to Treating Hepatitis C on the Prairies

Researchers Under the Scope

Release Date: 03/31/2025

Not Just Numbers: Vaidehee Lanke Tracks Opiate Use & Perinatal Health show art Not Just Numbers: Vaidehee Lanke Tracks Opiate Use & Perinatal Health

Researchers Under the Scope

In this episode, medical student and researcher  shares what large provincial datasets reveal about opioid use disorder, maternal mental health, and pregnancy. Armed with data, she hopes better support —before, during, and after birth—can change outcomes for mothers and babies.   Lanke spent her summer working with epidemiologist  and the Saskatchewan Population Health and Evaluation Research Unit on a pan-Canadian project tracking opioid use in perinatal populations across five provinces. “The question we set out to answer was: What is the association between...

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Cross-Linked Clues: Jack Walther on Depression and Alzheimer's show art Cross-Linked Clues: Jack Walther on Depression and Alzheimer's

Researchers Under the Scope

As a student, Jack Walther's friends often came to him when they needed a listening ear, or help with relationship struggles. This summer, Walther took his fascination with the brain and mood disorders to , learning to untangle some of the tiny molecular threads that might explain why depression so often shows up alongside dementia. Walther and the research team dug into the physical interactions between serotonin and the beta amyloid peptides that build up in patients with Alzheimer's disease. . He admits going from the classroom to the laboratory felt like a sharp learning curve. "It was...

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EEEV-ident Passion: Eve Simpson on Doubt, Persistence and Viral Spread show art EEEV-ident Passion: Eve Simpson on Doubt, Persistence and Viral Spread

Researchers Under the Scope

Eve Simpson knows from experience scientific research doesn’t always follow a linear path. In the first of three student research episodes, the fourth-year biochemistry, microbiology and immunology student looks back at a summer spent decoding Eastern Equine Encephalitis Virus (EEEV) in ’s lab. Simpson said she loved doing bench research, but felt frustrated in the moments where she hit setbacks and moments of doubt. “I felt like I was letting everyone down,” she said. “But everyone I spoke to said they'd been through that. It's part of being a researcher. That's what drives us to do...

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That’s So Metal: Dr. Jessica Sheldon Targets Acinetobacter Baumannii show art That’s So Metal: Dr. Jessica Sheldon Targets Acinetobacter Baumannii

Researchers Under the Scope

Jessica Sheldon (PhD) is on a mission to starve out Acinetobacter baumannii —one of the world’s most virulent hospital-borne pathogens. Notorious for its speedy evolution and multi-drug resistance, the hospital-borne bacteria lingers on dry surfaces and infects critically-ill patients, leading to sepsis, pneumonia and high mortality rates. In this episode, delves into the real-life events that drove her to investigate histamine, and its role in bacterial survival and immune response. In 2022, Sheldon joined the University of Saskatchewan’s College of Medicine as an assistant professor...

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Fluid Endeavour: Kirk Haan's Medical Balancing Act show art Fluid Endeavour: Kirk Haan's Medical Balancing Act

Researchers Under the Scope

Kirk Haan graduated from high school, thinking he’d study pharmacy at the University of Saskatchewan, and walk out five years later. After one summer at a pharmacy, Haan realized he was after a more ‘hands-on’ career in medicine. “I’ve kind of worked with my hands my whole life, just between rummaging around on a farm and always kind of building things,” he said.  “Now it’s using them to help people in a direct way.” Then, Haan found his passion — inside the laboratory. In 2018, Haan landed a summer position in , studying osmoregulation — the mechanisms that govern...

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Dr. Sébastien Gauvrit: Fishing for Answers in Vascular Development show art Dr. Sébastien Gauvrit: Fishing for Answers in Vascular Development

Researchers Under the Scope

Sébastien Gauvrit (PhD) was only ten when his family let him have his first tank of guppies. Within weeks, he was hooked. “I actually had to understand genetics directly by mixing these different fish together to get the colour or fin shape I was interested in,” said the vascular biologist and genetic modelling pioneer. From his home in France, to post-doctoral work pioneering new models for vascular disease in Germany, to his current position as an assistant professor of Anatomy, Physiology and Pharmacology at the University of Saskatchewan’s College of Medicine —  tropical fish...

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Dr. Stu Skinner & Mobile Medicine: Halting Syphilis & HIV show art Dr. Stu Skinner & Mobile Medicine: Halting Syphilis & HIV

Researchers Under the Scope

Stuart Skinner (MD) knew something was wrong three years ago, when patients started coming to him with vision loss, fever, rashes, and meningitis. Almost every case could be traced back to untreated syphilis — a sexually transmitted infection with caseloads exploding 1,200 per cent from 2017.  Saskatchewan saw this spike just as Covid-19 entered the picture. “With the pandemic, testing dropped dramatically,” Skinner said, noting this , often travelling alongside HIV. Syphilis often spreads through sores, and can remain unnoticed for months or years on end, making early detection...

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Peptide Puzzle: Dr. Yi-Chun Chen on Early Markers for Diabetes and Obesity show art Peptide Puzzle: Dr. Yi-Chun Chen on Early Markers for Diabetes and Obesity

Researchers Under the Scope

Yi-Chun Chen (PhD) is taking a close-up look at some of the body’s hardest-working cells — the ones often processing an overabundance of modern-day food and nutrients. “From an evolutionary point of view, our cells are not designed to deal with that,” said Chen, who joined the department of Anatomy, Physiology, and Pharmacology at the University of Saskatchewan last year as an assistant professor. She said our bodies are pushed into churning out large amounts of insulin rapidly after snacks and meals, “which makes the beta cells work extra hard.” Raised in Taiwan and inspired by...

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In the Trenches: Dr. James Stempien on Emergency Medicine show art In the Trenches: Dr. James Stempien on Emergency Medicine

Researchers Under the Scope

James Stempien (MD) has navigated some of the most challenging corners of emergency medicine, from the frigid isolation of Inuvik to the bustling corridors of Saskatoon’s emergency departments.  His experience in low-tech outposts has shaped his approach to modern emergency care.   “When things aren’t going well you see it in the emergency department first,” Stempien said. “We’re the front door. We’re always open.”   As provincial department head of emergency medicine, Stempien sees patients on their worst days in hospitals bursting at the seams, struggling to...

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All’s Not Lost: A Roadmap to Treating Hepatitis C on the Prairies show art All’s Not Lost: A Roadmap to Treating Hepatitis C on the Prairies

Researchers Under the Scope

As the world aims to eradicate hepatitis C (HCV) by 2030, Carrielynn Lund and Dr. Alexandra King’s team created a how-to guide.  is a step-by-step guide to tackling a spike of new infections across the three Canadian prairie provinces. Hepatitis C (HCV) causes severe liver disease, and was notoriously difficult to treat until the introduction of direct-acting antivirals a decade ago — antivirals which boast a remarkable 95% success rate. Despite this advancement, Lund and Dr. King say Saskatchewan, Alberta and Manitoba need to know why HCV cases keep rising, particularly in...

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As the world aims to eradicate hepatitis C (HCV) by 2030, Carrielynn Lund and Dr. Alexandra King’s team created a how-to guide.

 Journeys to Wellness: Prairie Hepatitis C Roadmap is a step-by-step guide to tackling a spike of new infections across the three Canadian prairie provinces.

Hepatitis C (HCV) causes severe liver disease, and was notoriously difficult to treat until the introduction of direct-acting antivirals a decade ago — antivirals which boast a remarkable 95% success rate.

Despite this advancement, Lund and Dr. King say Saskatchewan, Alberta and Manitoba need to know why HCV cases keep rising, particularly in jails, in remote communities, and in people who lack adequate housing and nutrition.

The virus is not picky, as Carrielynn Lund learned when she was first diagnosed in the 1990s. Her doctor wrongly told her back then the blood-borne illness could be spread only through injection drug use.

Shocked, Lund said “I went out of that room and drove home thinking, oh my God, I'm gonna die.”

A single mother of two, she resumed her professional life and never disclosed that “dark, dirty secret” until nearly 20 years later, as she became friends with Dr. King.

The Waniska team, led by Saydi Harlton, brought together researchers, health professionals, and people who’ve lived with hepatitis C in sharing circles, workshops and interviews.

“The stigma around this needed to be addressed and I wanted to be a part of it,” said Lund. “People often feel really alone in this journey, and it’s so important that we create spaces where they can share their stories and be heard."

Participants identified barriers to care, including confidentiality breaches, misinformation and inadequate access to testing.

“My priority right now may or may not be my hepatitis C. It might be, where am I going to sleep today? Or, what food am I going to be getting?” said Dr. King.

In the Roadmap, King said the disproportionately high number of cases in Indigenous people shows a need for true elimination strategies, rather than pockets of “little pilot projects.”

"There aren't necessarily a lot of resources, so you're dealing with fairly fragile systems," Dr. King noted.

Recent provincial government decisions to axe needle exchanges, and cut public transportation routes to remote and northern communities have taken their toll, she added.

Given the hurdles faced by Indigenous and two-spirit people, both Dr. King and Lund say prairie people need culturally informed care. They point to Indigenous-led hepatitis C elimination strategies with predictable funding and resources.  

“It really helps you to understand the importance of really good evidence-based policy that supports people and meet them where they're at,” Dr. King said.

Lund and Dr. King believe making a fiscal case for early detection and treatment may also swing policy-makers back toward patient-centred care.

Peer support also plays a role, Lund said.

“When someone who has been through it helps a newly diagnosed person, it can truly change everything for them," she said.