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#68 Advances in Management of Sickle Cell Disease

Pedia Pain Focus

Release Date: 06/24/2021

#92. Is Physical Therapy, The Panacea of Chronic Pain? show art #92. Is Physical Therapy, The Panacea of Chronic Pain?

Pedia Pain Focus

Have you ever had any of your patients say that they don't think physical therapy helps their pain? Or that the physical therapy made their pain worse? It would certainly not surprise me, if you said yes. And in that case, this is definitely is the episode you want to listen to carefully.  And if your answer to my question was no, this is an episode for you too, my friend. Because sooner or later you too will join this elite club with rest of us. However, this episode will give you the framework and tools to change that in your practice.  Learn it from our guest who magically...

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#91. Mental Health and Pediatric Pain; Chicken or the Egg? show art #91. Mental Health and Pediatric Pain; Chicken or the Egg?

Pedia Pain Focus

Pain and mental illnesses coexist, often more than any of other illnesses. Both of them have a profound effect on a child's child’s quality of life, individually.  Now imagine the magnitude of impact  when they co-exist.   In this episode, Dr. Anjana Kundu, with guest speaker Dr. Mirabelle Mattar, a child, and adolescent psychiatrist, discusses the intricate and dynamic relationship between pediatric pain and mental health, likely cause or affect and prognosis for a child with pain in the setting of mental health issues or vice-versa.  They also discussed the factors...

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#90. Can We Prevent Pain from Becoming Chronic? show art #90. Can We Prevent Pain from Becoming Chronic?

Pedia Pain Focus

Acute pain may be a protective and adaptive phenomenon, but chronic pain is nothing but damaging and a burden in every way possible and for all involved directly or indirectly. So how do we reduce or can we reduce burden?   Join me in this episode to learn the factors that contribute to chronicity of pain and whether we can prevent it.   Takeaways in This Episode Complexities of pain and its impact for the individuals and the society What differentiates acute from chronic pain and why that is important Various factors contributing to pain and its chronicity Modifiable vs....

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#89. The Pain of Being a Redhead show art #89. The Pain of Being a Redhead

Pedia Pain Focus

An anesthesiologist or a dentist might tell you that redheads need more anesthesia or local anesthetic. Yet research around their pain perception, tolerance, modulation and response to different pain medications is much more variable and complicated. Join me to learn the recent and emerging evidence about the pain among redheads and what you can do for effectively and safely managing it!

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#88. Pharmacovigilance to Evaluate Efficacy and Net Clinical Benefit in Pediatric Pain Medicine show art #88. Pharmacovigilance to Evaluate Efficacy and Net Clinical Benefit in Pediatric Pain Medicine

Pedia Pain Focus

What if you had the lessons from the hindsight AND the foresight while managing children's pain? How would that change your practice? How would that change the outcomes of pediatric pain treatments?

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87. Shifting the Paradigm in Pediatric Pain Medicine show art 87. Shifting the Paradigm in Pediatric Pain Medicine

Pedia Pain Focus

Pediatric pain has long been and continues to be neglected for many reasons and because of many challenges. In this episode we discuss those factors and more importantly, the way forward to make the paradigm shift, overcoming challenges and recognizing opportunities.

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#86. Essential Elements of a Successful Patient Encounter show art #86. Essential Elements of a Successful Patient Encounter

Pedia Pain Focus

A clinical care visit is like flying a plane. It has to be smooth (charming), safe (thorough) yet efficient and on time!

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#85. Pain Amongst Children with Autism Spectrum Disorder show art #85. Pain Amongst Children with Autism Spectrum Disorder

Pedia Pain Focus

Rising prevalence of Autism Spectrum Disorders, contradicting opinions and misconceptions around pain sensitivity and expression among these patients pose unique challenges for clinicians.

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#84. Post-Concussive Headache and Symptom Management in Children show art #84. Post-Concussive Headache and Symptom Management in Children

Pedia Pain Focus

Headache is a presenting symptom in 90% of children after a traumatic head injury and for many it may persist for years. It can be extremely debilitating and difficult to treat, posing several unique diagnostic and therapeutic challenges. Join me in conversation with Blake Windsor, MD a pediatrician with a subspecialty in training for pediatric pain medicine, a board certified headache specialist and Chief of Primas Health Pediatric Pain Medicine.

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#83. Reengineering Pediatric Perioperative Care for Optimal Outcomes show art #83. Reengineering Pediatric Perioperative Care for Optimal Outcomes

Pedia Pain Focus

Postoperative outcomes and success of the interventions is certainly dependent on the analgesia and anesthesia care, but what truly drives the outcomes is a complex interplay of biopsychosocial factors; an alignment between the patients and family's goals and medical as well as surgical interventions. How one goes about achieving that is what this episode is all about!

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More Episodes

pain is the most common and devastating symptom of Sickle Cell Disease. Despite the slow and elusive developement of therapeutic intervention in Sickle cell disease that would halt the vasocclusive crisis and the related pain, last few decades have brought about good progress with successful hemopoetic stem cell transplant as well as several therapeutic agents targeting various aspect of teh pathophysiliogy of SCD.

 

In this episode, I review the 4 major targets in the pathophysiology of SCD and approved therapeutic interventions and agents as well as those that are further along clinical trial with very promising results.

 

Takeaways in This Episode

  • What prompted me to do this update
  • How this episode is different from and how it complements the earlier published episode about sickle cell disease
  • The challenges presented by sickle cell disease
  • The major presentation and impact of sickle cell disease
  • 4 main therapeutic targets with advances and ongoing trials
  • Newer FDA approved agents in management of vasocclusive crisis and pain
  • The success and challenges of stem cell transplant for SCD

 

Links

Pedia Pain Focus Episode #12. Master Your Sickle Cell Pain Care Skills

Pedia Pain Focus Episode #62. Metaphors for Better Pediatric Pain Management 

Pedia Pain Focus Episode #21. How to Counsel your Patients on Off-Label Medication Use

Proactive Pain Solutions Physicians Academy

Proactive Pain Solutions