loader from loading.io

Psychedelic Medicine: Updates from the field with Lynn Marie Morski, JD, MD

Psychedelic Medicine Podcast with Dr. Lynn Marie Morski

Release Date: 11/13/2025

Psychedelics and Neurodiversity with Dr. WaiFung Tsang, DClinPsy show art Psychedelics and Neurodiversity with Dr. WaiFung Tsang, DClinPsy

Psychedelic Medicine Podcast with Dr. Lynn Marie Morski

In this episode, Dr. WaiFung Tsang, DClinPsy joins to discuss the intersection of psychedelics and neurodiversity. Dr. Tsang is a clinical research psychologist from Hong Kong, musician, and student of Shipibo curanderismo. He is the co-founder of Onaya, an organisation dedicated to bridging Indigenous tradition and Western science, and research advisor for psychedelic veteran charity Heroic Hearts Project. In this conversation, Dr. Tsang explores the emerging intersection of psychedelics and neurodiversity, reframing neurodivergence as a context-dependent spectrum shaped by biology, culture,...

info_outline
Spravato: The Accessible Psychedelic Medicine with Amy Della Rocca, PMHNP show art Spravato: The Accessible Psychedelic Medicine with Amy Della Rocca, PMHNP

Psychedelic Medicine Podcast with Dr. Lynn Marie Morski

In this episode Amy Della Rocca, PMHNP joins to discuss Spravato, the FDA-approved prescription esketamine nasal spray, and its place in the field of psychedelic medicine. Amy is a psychiatric nurse practitioner and the Clinical Director of Marpa, a Spravato treatment center in New York. In this conversation, Amy offers a grounded and practical look at Spravato as one of the most accessible forms of psychedelic medicine currently available, especially for patients with treatment-resistant depression who may be priced out of intravenous or intramuscular ketamine treatments. She explains how...

info_outline
Low-Dose Ketamine for Chronic Pain: A Biopsychosocial Approach with Michelle Weiner, DO, MPH show art Low-Dose Ketamine for Chronic Pain: A Biopsychosocial Approach with Michelle Weiner, DO, MPH

Psychedelic Medicine Podcast with Dr. Lynn Marie Morski

In this episode, Michelle Weiner, DO, MPH returns to share her expertise on low-dose ketamine for chronic pain. Dr. Weiner is double board-certified in Interventional Pain Medicine, Physical Medicine, and Rehabilitation. She is founder of Neuropain Health delivering personalized integrative care treating the root cause of pain and suffering, both physical and emotional, using a multidisciplinary biopsychosocial approach with many years of clinical experience with ketamine-assisted therapy. In this conversation, Dr. Weiner reframes chronic pain as more than a symptom of tissue damage,...

info_outline
Ayahuasca for PTSD with Dr. Simon Ruffell MBChB, MRCPsych, PhD show art Ayahuasca for PTSD with Dr. Simon Ruffell MBChB, MRCPsych, PhD

Psychedelic Medicine Podcast with Dr. Lynn Marie Morski

In this episode Dr. Simon Ruffell joins to discuss the research on ayahuasca for PTSD. Dr. Ruffell is a psychiatrist, researcher, and student of curanderismo (Amazonian shamanism) working at the intersection of Western psychiatry, traditional plant medicine, and Indigenous knowledge systems. He is Executive Director of Onaya, Lecturer in Psychology and Psychedelics at the University of Exeter, and Chief Medical Officer of MINDS, with a focus on integrative and relational approaches to healing and consciousness. In this conversation, Dr. Ruffell explores the emerging research on ayahuasca as a...

info_outline
Impacts of Social Inequality on Psychedelic Healing with Sean Viña, PhD show art Impacts of Social Inequality on Psychedelic Healing with Sean Viña, PhD

Psychedelic Medicine Podcast with Dr. Lynn Marie Morski

In this episode, Dr. Sean M. Viña joins to discuss the ways that social inequality can impact psychedelic healing. Dr. Viña is a sociologist with a PhD from Indiana University whose research focuses on psychedelics and mental health, and social inequality. In this conversation, Dr. Viña explains that while psychedelics are often framed as transformative treatments, their benefits appear unevenly distributed and frequently constrained by structural factors such as income inequality, education, stigma, caregiving burden, segregation, and social isolation. The discussion highlights how...

info_outline
Psychedelics and Religion with Hunt Priest, MDiv show art Psychedelics and Religion with Hunt Priest, MDiv

Psychedelic Medicine Podcast with Dr. Lynn Marie Morski

In this episode, Hunt Priest joins to discuss the intersection of psychedelic experiences and religion. Hunt is the founder of Ligare: A Christian Psychedelic Society and was a participant in the Johns Hopkins/NYU Psilocybin Study for Religious Leaders in 2016. The epiphanies he had at Hopkins forever changed the trajectory of his work and led him to start Ligare in 2021. In this conversation, Hunt Priest reflects on how participating in the Johns Hopkins study reshaped his understanding of Christianity, embodiment, and spiritual experience. Drawing on his background as an Episcopal priest, he...

info_outline
Encore Episode: How Psychedelics Affect the Brain with Manesh Girn, PhD show art Encore Episode: How Psychedelics Affect the Brain with Manesh Girn, PhD

Psychedelic Medicine Podcast with Dr. Lynn Marie Morski

In this encore episode of the Psychedelic Medicine Podcast, psychedelic science researcher and educator Dr. Manesh Girn discusses his studies investigating psychedelic brain action. Manesh earned PhD in neuroscience at McGill University and is an author on over a dozen peer-reviewed articles on psychedelics and related topics. He is also chief research officer at EntheoTech Bioscience and runs the YouTube channel the Psychedelic Scientist.  In this conversation, Manesh discusses his recent article in Trends in Cognitive Sciences titled He explains the complexity science approach used...

info_outline
Which Psychedelic for Which Condition? with Will Van Derveer, MD show art Which Psychedelic for Which Condition? with Will Van Derveer, MD

Psychedelic Medicine Podcast with Dr. Lynn Marie Morski

In this episode, Will Van Derveer, MD joins to unpack what we know about which psychedelic medicines are best suited to particular mental health conditions. Dr. Van Derveer has trained several thousand mental health professionals in psychedelic-assisted psychotherapy, provided ketamine assisted therapy to hundreds of people, and has staffed MDMA therapy trials with MAPS. His book, Psychedelic Therapy: A Revolutionary Approach to Restoring Your Mental Health and Reclaiming Your Life, will be published by Shambala in the spring of 2026. In this conversation, Dr. Van Derveer offers a...

info_outline
Psychedelics for the Menopause Transition with Alicia Bigelow, ND show art Psychedelics for the Menopause Transition with Alicia Bigelow, ND

Psychedelic Medicine Podcast with Dr. Lynn Marie Morski

In this episode, Alicia Bigelow, ND joins to discuss the potential of psychedelic medicine to support the menopause transition. Dr. Ali Bigelow is a naturopathic physician, ketamine provider and licensed psilocybin facilitator in Portland, OR. She leads individual and group retreats, enjoys incorporating live music into her sessions when desired, and is passionate about supporting those navigating life transitions, such as end of life and menopause, through her low dose group, Menomorphosis. Dr. Bigelow will be doing retreats in 2026 with Rise Up Journeys at In this conversation, Dr. Bigelow...

info_outline
Psychedelics as Catalysts for Human Agency with Matthew W. Johnson, PhD show art Psychedelics as Catalysts for Human Agency with Matthew W. Johnson, PhD

Psychedelic Medicine Podcast with Dr. Lynn Marie Morski

In this episode, Matthew W. Johnson, PhD returns to discuss how psychedelics can be leveraged to catalyze human agency. Dr. Johnson has been at the forefront of psychedelic research for 21 years, having conducted seminal research on the effects of psilocybin on mystical experience, personality, and treatment of cancer distress, major depressive disorder, and tobacco addiction. His work with tobacco addiction received the first federal funding for a classic psychedelic in the modern era of research. In this conversation, Dr. Johnson explores psychedelics as powerful enhancers of human...

info_outline
 
More Episodes

In this episode, Psychedelic Medicine Podcast host, Dr. Lynn Marie Morski, provides the latest updates from the field of psychedelic medicine. Dr. Morski discusses the breakthrough therapy designation which a number of psychedelic compounds have received in the past few years, the most recent of which is BPL-003, a nasal spray formulation of 5-MeO-DMT. One of the exciting aspects of this new compound, Dr. Morski notes, is that it is shorter-acting than most serotonergic psychedelics—a feature which may make treatment with this substance less expensive and more accessible. 

Another exciting development is the COMPASS Pathways phase 3 trial of COMP360 psilocybin. Dr. Morski shares that the company believes they are nine to twelve months ahead of schedule, which means that if all goes well, this psilocybin compound could be approved for treatment resistant depression as early as sometime in 2027. She also discusses why the US FDA said they rejected MDMA for PTSD and what this governing body would like to see from subsequent research before reconsidering this decision. In closing, Dr. Morski shares excitement about the development of novel psychoplastogens—the non-hallucinogenic psychedelics—which may help bring many of the same healing benefits to populations currently unable to be served by the existing compounds under investigation.

 

In this episode, you'll hear:

  • Which psychedelics currently have breakthrough therapy designation and for which indications
  • Details of recent ketamine research for inpatient depression care and why these results are not as negative as they may seem
  • The current horizons of psychedelic research and what indications may soon be explored
  • Sources of hope in the current state of psychedelic research and the legal landscape

 

Quotes:

“[BPL-003] showed rapid and durable antidepressant outcomes after a single dose. … here we have something that is under an hour [of psychedelic experience] for treatment resistant depression.” [7:43]

“Keeping patients blinded to whether or not they got the placebo or MDMA is a big focus that [the FDA] wanted to emphasize for these future phase 3 trials.” [19:07]

“I know we had a big setback last year. I think a lot of us thought by this time we'd be a year into MDMA being approved and we're not. However, there are so many things on the horizon that are worth being excited about.” [23:48]

 

Links:

Psychedelic Medicine Podcast on Instagram

Psychedelic Medicine Podcast on YouTube

Jelovac A, McCaffrey C, Terao M, et al. “Serial Ketamine Infusions as Adjunctive Therapy to Inpatient Care for Depression: The KARMA-Dep 2 Randomized Clinical Trial” JAMA Psychiatry, 2025.

Beckley Psytech Limited Phase 2 Trial: BPL-003 Efficacy and Safety in Treatment Resistant Depression

COMPASS Pathways Phase 3 Trial: Efficacy, Safety, and Tolerability of COMP360 in Participants With TRD

Food and Drug Administration (FDA) Complete Response Letter (CRL) to Lykos Therapeutics, declining to approve MDMA-assisted therapy for Posttraumatic Stress Disorder

Psychedelic Alpha Psychedelic Drug Development Bullseye Chart

Psychedelic Medicine Association

Porangui