Ep. 250 "The Future of Psoriasis Care: Dr. Mona Shahriari Breaks Down New AAD Research & Personalized Treatments"
Release Date: 04/29/2025
Psoriasis Uncovered
Description: Do you wonder if TB testing is needed when on a biologic for psoriasis and/or psoriatic arthritis and why? Hear the answer to such questions and more from dermatologist Dr. G. Scott Drew as he addresses recent recommendations. Join host Archie Franklin as he discusses the latest recommendations from NPF and the International Psoriasis Council about routine testing for tuberculosis (TB) with treatments for psoriasis and psoriatic arthritis such as TNF-inhibitors, IL-17’s, IL-23’s and others with NPF Medical Board member and...
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Description: How do GLP-1 receptor agonists or GIP agonists work and what is the impact for my psoriatic disease? Hear dermatologist Dr. Ronald Prussick and cardio-immunologist Dr. Brittany Weber answer such questions and more. Join host Archie Franklin as he takes a deep dive into the use of GLP-1 receptor agonists and GIP agonists and the convergence of systemic inflammation related to psoriatic disease with renowned dermatologist and Vice Chair of the NPF Medical Board, Dr. Ronald Prussick from Washington Dermatology Center...
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Description: “When joint pain is present, the diagnosis of psoriatic arthritis needs to be made as soon as possible, ideally within six months to limit joint inflammation” Dr. Vinod Chandran mentions as he discusses efforts to identify a diagnostic test for those at risk of developing psoriatic arthritis. Join host Jeff Brown as he speaks with leading rheumatologist and clinician scientist Dr. Vinod Chandran, Director of the Gladman Krembil Psoriatic Arthritis Program, Schroeder Arthritis Institute, University Health Network and the...
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Description: “What is metabolic disease and why do I have it on top of psoriatic disease?” Hear dermatologist Dr. Ronald Prussick and registered dietitian Danielle Cahalan explore this collision of diseases and how you can take control to help reduce the impact of inflammation. Join host Corinne Rutkowski as she discusses why metabolic disease occurs with psoriasis and psoriatic arthritis and what can be done to improve overall health with dermatologist and Vice Chair of the NPF Medical Board, Dr. Ronald Prussick from Washington...
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Description: Coping with psoriasis can be challenging when your routine changes. Hear NPF Youth Ambassadors Aditi, Alyssa, and Pierce offer what they do to overcome such challenges when out of their routine. Join host Kaleigh Welch as she discusses tips for coping with changes that occur when traveling to visit family or friends, going on vacation, camping, or a change in schedule with three amazing NPF Youth Ambassadors Aditi, Alyssa, and Pierce who live with psoriasis. Hear their story from challenges with their initial diagnosis,...
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After being diagnosed with psoriasis and psoriatic arthritis, finding a community that understood how life changed meant everything to Jody Quinn, Ben and Kathryn Rifenbark. Join host Alan Simmons as he addresses life with psoriasis and psoriatic arthritis before and after finding the National Psoriasis Foundation with 3 amazing volunteers – Jody Quinn, Ben and Kathryn Rifenbark. Hear their story from struggles with initial diagnosis, being an advocate for their own health care, to how they chose to become part of a community and help...
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Description: Learn why advocating for care is crucial when moderate to severe plaque psoriasis develops at a young age or in high-impact sites, and how advanced biologic therapies can offer effective solutions for those that may be undertreated. Join moderator Kaitlin Walden, patient advocate Carolyn, and dermatologist Dr Candrice Heath as they discuss the realities of living with moderate to severe plaque psoriasis at a young age, as well as adult patients with plaque psoriasis in high-impact sites, like the scalp, nails, and face. Carolyn shares her personal journey with moderate to severe...
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Hear leading dermatologist Dr. E. James Song and patient advocate Ana Rinck share their perspectives on the use of biosimilars to manage psoriasis and psoriatic arthritis. The use of biosimilars is growing with 24 currently on the market and more on the way for the treatment of psoriasis and psoriatic arthritis. What does this mean for you? Find out as we explore the use of biosimilars, the impact of interchangeability, what it’s like switching to a biosimilar, and what questions to ask your health care provider with leading dermatologist and NPF Medical Board member Dr. E. James Song,...
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Description: Nail psoriasis is tough to treat. Hear Rebecca, a patient who lives with nail psoriasis, and dermatologist Dr. Paul Yamauchi discuss the diagnosis, care, and treatment for this high-impact site. Join host Roy Pankey as he addresses the complexities of nail psoriasis from diagnosis to coping and the latest research and treatments with leading dermatologist, Dr. Paul Yamauchi from the Dermatology Institute and Skin Care Center and Clinical Science Institute, and Rebecca, a patient advocate with the National Psoriasis...
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“Help! It’s winter and my psoriasis and psoriatic arthritis is flaring.” Listen as certified physician assistant Eileen Cheever offers tips to help manage psoriasis and psoriatic arthritis flares that occur during the winter months. Join host Corinne Rutkowski as she explores tips for managing psoriasis and psoriatic arthritis when cold weather flares the disease with Certified Physician Assistant Eileen Cheever from Clearview Dermatology. Listen as they discuss why flares occur and tips for improving flares from humidity,...
info_outlineExplore groundbreaking updates in psoriasis and psoriatic arthritis research from the 2025 AAD Annual Meeting with dermatologist Dr. Mona Shahriari.
Join host Archie Franklin and renowned dermatologist Dr. Mona Shahriari as they unpack the latest research and clinical insights into managing psoriatic disease. This episode dives into head-to-head therapeutic trials, fast-acting treatments for high-impact areas like scalp and nails, and a preview of emerging oral biologics and GLP-1 weight management therapies. Dr. Shahriari discusses real-world challenges in treating psoriasis and psoriatic arthritis, the rise of precision medicine, and how early intervention could alter disease progression.
Whether you're a patient, clinician, or researcher, this conversation delivers critical updates on psoriasis care, including IL-17, IL-23, and TYK2 inhibitors, and their potential to revolutionize dermatology practice.
Timestamps:
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(00:00) Intro to Psound Bytes & guest welcome Dr. Mona Shahriari
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(01:00) What the AAD 2025 conference revealed about psoriatic disease
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(02:10) Comparing IL-17 and IL-23 inhibitors: Trial results
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(06:00) Treating scalp, palmoplantar, and nail psoriasis
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(10:45) Genital psoriasis & the importance of psychosocial care
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(12:00) What’s new for Generalized Pustular Psoriasis (GPP)
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14:35) The GUIDE Study: Early treatment & immune memory
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(18:00) Personalized medicine, oral IL-23s & emerging TYK2s
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(20:00) GLP-1 therapies for weight & inflammation control
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(23:00) Psoriasis, cardiovascular risk & comorbidities
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(24:00) Mental health, depression & the value of systemic treatment
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(26:00) A hopeful future: matching therapy to the patient
4 Key Takeaways:
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Head-to-head trials show IL-17s like ixekizumab outperform traditional TNF inhibitors and even some IL-23s in early, fast action.
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Precision therapy based on site (scalp, nails, genitalia) and comorbidities is now guiding real-world treatment selection.
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GLP-1 medications are emerging as effective adjuncts for psoriasis patients struggling with weight and inflammation.
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Early intervention—especially with IL-23 inhibitors—may reduce flares, limit disease progression, and improve mental health outcomes.
Guest Bio:
Dr. Mona Shahriari is an Associate Clinical Professor of Dermatology at Yale University and Co-Founder of Central Connecticut Dermatology. A leading voice in inflammatory skin conditions, she serves as Associate Director of Clinical Trials and Senior Editor for the Journal of Psoriasis and Psoriatic Arthritis, a National Psoriasis Foundation peer reviewed journal for health care providers. Dr. Shahriari is also a National Psoriasis Foundation Medical Board Member and frequent contributor to dermatological research and clinical education.
Resources Mentioned:
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National Psoriasis Foundation: https://www.psoriasis.org
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Subscribe to the Advance eNewsletter: https://www.psoriasis.org/subscribe
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AAD Annual Meeting Info: https://www.aad.org
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Learn More About Clinical Trials: https://clinicaltrials.gov
Tags:
psoriasis, psoriatic arthritis, IL-17, IL-23, biologics, personalized medicine, dermatology, GLP-1, weight management, immune memory, AAD 2025, TYK2 inhibitors, Dr. Mona Shahriari, National Psoriasis Foundation, Psound Bytes podcast, Soundbites podcast