Ep 252 "Defining Minimal Disease Activity in Psoriatic Arthritis with rheumatologist Dr. Arthur Mandelin"
Release Date: 05/13/2025
Ep. 279 "To Test for TB or Not: Latest Recommendations for Psoriatic Disease Treatments"
Psoriasis Uncovered
Description: Do you wonder if TB testing is needed when on a biologic for psoriasis and/or psoriatic arthritis and why? Hear the answer to such questions and more from dermatologist Dr. G. Scott Drew as he addresses recent recommendations. Join host Archie Franklin as he discusses the latest recommendations from NPF and the International Psoriasis Council about routine testing for tuberculosis (TB) with treatments for psoriasis and psoriatic arthritis such as TNF-inhibitors, IL-17’s, IL-23’s and others with NPF Medical Board member and...
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Ep. 278 "GLP-1 & GIP Therapies: What They Mean for Psoriasis and Psoriatic Arthritis"
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Description: How do GLP-1 receptor agonists or GIP agonists work and what is the impact for my psoriatic disease? Hear dermatologist Dr. Ronald Prussick and cardio-immunologist Dr. Brittany Weber answer such questions and more. Join host Archie Franklin as he takes a deep dive into the use of GLP-1 receptor agonists and GIP agonists and the convergence of systemic inflammation related to psoriatic disease with renowned dermatologist and Vice Chair of the NPF Medical Board, Dr. Ronald Prussick from Washington Dermatology Center...
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Ep.277 "Progress Towards Identifying a Psoriatic Arthritis Diagnostic Test"
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Description: “When joint pain is present, the diagnosis of psoriatic arthritis needs to be made as soon as possible, ideally within six months to limit joint inflammation” Dr. Vinod Chandran mentions as he discusses efforts to identify a diagnostic test for those at risk of developing psoriatic arthritis. Join host Jeff Brown as he speaks with leading rheumatologist and clinician scientist Dr. Vinod Chandran, Director of the Gladman Krembil Psoriatic Arthritis Program, Schroeder Arthritis Institute, University Health Network and the...
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Ep.276 "The Metabolic Collision and How You Can Take Control with Psoriatic Disease"
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Description: “What is metabolic disease and why do I have it on top of psoriatic disease?” Hear dermatologist Dr. Ronald Prussick and registered dietitian Danielle Cahalan explore this collision of diseases and how you can take control to help reduce the impact of inflammation. Join host Corinne Rutkowski as she discusses why metabolic disease occurs with psoriasis and psoriatic arthritis and what can be done to improve overall health with dermatologist and Vice Chair of the NPF Medical Board, Dr. Ronald Prussick from Washington...
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Ep. 275 "Tips for Managing Psoriasis When Life Takes You Out of Your Routine"
Psoriasis Uncovered
Description: Coping with psoriasis can be challenging when your routine changes. Hear NPF Youth Ambassadors Aditi, Alyssa, and Pierce offer what they do to overcome such challenges when out of their routine. Join host Kaleigh Welch as she discusses tips for coping with changes that occur when traveling to visit family or friends, going on vacation, camping, or a change in schedule with three amazing NPF Youth Ambassadors Aditi, Alyssa, and Pierce who live with psoriasis. Hear their story from challenges with their initial diagnosis,...
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Ep. 274 "Finding Connections Made Us Stronger with the National Psoriasis Foundation"
Psoriasis Uncovered
After being diagnosed with psoriasis and psoriatic arthritis, finding a community that understood how life changed meant everything to Jody Quinn, Ben and Kathryn Rifenbark. Join host Alan Simmons as he addresses life with psoriasis and psoriatic arthritis before and after finding the National Psoriasis Foundation with 3 amazing volunteers – Jody Quinn, Ben and Kathryn Rifenbark. Hear their story from struggles with initial diagnosis, being an advocate for their own health care, to how they chose to become part of a community and help...
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Ep. 273 "Moderate to Severe Plaque Psoriasis in Children and in Adults with High-Impact Site Involvement"
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Description: Learn why advocating for care is crucial when moderate to severe plaque psoriasis develops at a young age or in high-impact sites, and how advanced biologic therapies can offer effective solutions for those that may be undertreated. Join moderator Kaitlin Walden, patient advocate Carolyn, and dermatologist Dr Candrice Heath as they discuss the realities of living with moderate to severe plaque psoriasis at a young age, as well as adult patients with plaque psoriasis in high-impact sites, like the scalp, nails, and face. Carolyn shares her personal journey with moderate to severe...
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Ep. 272 "Insights on the Use of Biosimilars for Psoriatic Disease"
Psoriasis Uncovered
Hear leading dermatologist Dr. E. James Song and patient advocate Ana Rinck share their perspectives on the use of biosimilars to manage psoriasis and psoriatic arthritis. The use of biosimilars is growing with 24 currently on the market and more on the way for the treatment of psoriasis and psoriatic arthritis. What does this mean for you? Find out as we explore the use of biosimilars, the impact of interchangeability, what it’s like switching to a biosimilar, and what questions to ask your health care provider with leading dermatologist and NPF Medical Board member Dr. E. James Song,...
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Ep. 271 "Hope and Healing: Treating Nail Psoriasis"
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Description: Nail psoriasis is tough to treat. Hear Rebecca, a patient who lives with nail psoriasis, and dermatologist Dr. Paul Yamauchi discuss the diagnosis, care, and treatment for this high-impact site. Join host Roy Pankey as he addresses the complexities of nail psoriasis from diagnosis to coping and the latest research and treatments with leading dermatologist, Dr. Paul Yamauchi from the Dermatology Institute and Skin Care Center and Clinical Science Institute, and Rebecca, a patient advocate with the National Psoriasis...
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Ep. 270 "Cold Weather, Hot Flares: Winter Survival Tips for Psoriasis and PsA"
Psoriasis Uncovered
“Help! It’s winter and my psoriasis and psoriatic arthritis is flaring.” Listen as certified physician assistant Eileen Cheever offers tips to help manage psoriasis and psoriatic arthritis flares that occur during the winter months. Join host Corinne Rutkowski as she explores tips for managing psoriasis and psoriatic arthritis when cold weather flares the disease with Certified Physician Assistant Eileen Cheever from Clearview Dermatology. Listen as they discuss why flares occur and tips for improving flares from humidity,...
info_outlineNot sure what Minimal Disease Activity or MDA is and how it relates to psoriatic arthritis and your joints? Listen as rheumatologist Dr. Arthur Mandelin explains what MDA means.
Join hosts Jeff Brown and LB Herbert as they discuss minimal disease activity in psoriatic arthritis with nationally recognized rheumatologist Dr. Arthur Mandelin who identifies what it is, factors that influence achieving MDA, how long it takes to reach, and the impact on selection of treatments. Dr. Mandelin also addresses fatigue associated with inflammation, and what the future holds for minimal disease activity in psoriatic arthritis.
Whether you have psoriasis or psoriatic arthritis, this episode offers information to help you understand management goals set by your doctor and the importance of attaining minimal disease activity.
Timestamps:
- (00:00) Intro to Psound Bytes & guest welcome rheumatologist Dr. Arthur Mandelin
- (02:23) What is minimal disease activity (MDA)
- (04:32) MDA in comparison to ACR response criteria
- (07:36) Criteria for reaching MDA
- (09:20) Positive and negative factors of MDA
- (11:25) Importance of reaching MDA within a specific time frame
- (17:34) Length of time to reach MDA
- (18:48) Selection of treatment options and psoriatic arthritis domains
- (23:51) Inflammation and fatigue
- (26:59) A look at the future of minimal disease activity in psoriatic arthritis: Reaching ACR 90
- (29:09) Advancements in psoriatic arthritis: Finding disease markers
- (33:40 ) If you have psoriasis, be aware of your risk for psoriatic arthritis
4 Key Takeaways:
- There are various ways to measure minimal disease activity in psoriatic arthritis to assess how the disease impacts quality of life.
- Attaining and keeping minimal disease activity low through use of different therapy options offers a chance for better bone and joint outcomes.
- Advancements in psoriatic arthritis include attaining ACR90 and the potential for identifying key markers that make treatment selection more targeted and individualized.
- Those who have psoriasis need to realize bone and joint pain, and swelling in the joints may be related to their psoriatic skin disease and seek appropriate help.
Guest Bio:
Dr. Arthur Mandelin is an Associate Professor of Medicine at Northwestern University Feinberg School of Medicine and the Department of Medicine Division of Rheumatology. Dr. Mandelin launched Northwestern University’s first training program in musculoskeletal ultrasonography for rheumatology fellows. He is an active participant in the REASON Group which is a multi-center research collaboration devoted to using ultrasound guidance to obtain minimally invasive synovial tissue biopsies. Dr. Mandelin is a past member of the National Psoriasis Foundation’s Medical Board where he served on consensus panels for the development of a variety of practice guidelines.
Resources Mentioned:
- National Psoriasis Foundation: https://www.psoriasis.org
- PEST Screener: https://www.psoriasis.org/psoriatic-arthritis-screening-test/
- PsA Action Month 2025: https://www.psoriasis.org/psa-action-month/
- NSAIDS for Psoriatic Disease: https://www.psoriasis.org/advance/nsaids-for-psoriatic-disease-psa/
- AMP (Accelerated Medicines Partnership): https://www.psoriasis.org/advance/progress-and-success- through-collaboration/
Tags:
psoriasis, skin, psoriatic arthritis, minimal disease activity, ACR20, ACR50, ACR70, tender joints, bone erosion, joint swelling, enthesitis, inflammation, pain, fatigue, axial disease, spinal involvement, treatment, NSAIDS, biologics, personalized medicine, dermatology, National Psoriasis Foundation, AMP, Psound Bytes podcast, Soundbites podcast