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Ep 252 "Defining Minimal Disease Activity in Psoriatic Arthritis with rheumatologist Dr. Arthur Mandelin"

Psound Bytes™

Release Date: 05/13/2025

Ep. 254 Ep. 254 "If You Have Psoriatic Disease Keep an Eye Out for Uveitis"

Psound Bytes™

Have a red, painful eye that’s sensitive to light? Could be uveitis. Hear ophthalmologist Dr. Timothy Janetos discuss uveitis and how it relates to psoriasis and psoriatic arthritis. Join host Takieyah Mathis for an eye opening discussion about uveitis, cataracts, and eye health with ophthalmologist Dr. Timonthy Janetos from Northwestern Medicine, Department of Ophthalmology. Listen as they discuss what is uveitis and cataracts from key symptoms, the significance of the HLA-B27 marker, diagnosis, to treatment options that help reduce inflammation and preserve long term vision. This episode...

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Ep. 253 Ep. 253 "Inflammation is Bad for Bone: Osteoporosis and Psoriatic Disease"

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Osteoporosis is a silent disease. There is no pain or other symptoms but inflammation in the gut and joints is a risk factor. Learn about your risks and what you can do for osteoporosis from rheumatologist Dr. Diana Sandler. Join host Corinne Rutkowski, a third year medical student, as she explores the relationship between osteoporosis and psoriasis with leading bone health expert and rheumatologist Dr. Diana Sandler. Listen as they discuss the difference between osteoporosis and osteoarthritis, bone density testing, how prolonged inflammation is a key risk factor especially for psoriatic...

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Ep 252 Ep 252 "Defining Minimal Disease Activity in Psoriatic Arthritis with rheumatologist Dr. Arthur Mandelin"

Psound Bytes™

Not sure what Minimal Disease Activity or MDA is and how it relates to psoriatic arthritis and your joints? Listen as rheumatologist Dr. Arthur Mandelin explains what MDA means. Join hosts Jeff Brown and LB Herbert as they discuss minimal disease activity in psoriatic arthritis with nationally recognized rheumatologist Dr. Arthur Mandelin who identifies what it is, factors that influence achieving MDA, how long it takes to reach, and the impact on selection of treatments. Dr. Mandelin also addresses fatigue associated with inflammation, and what the future holds for minimal disease activity in...

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Ep. 251 Ep. 251 "Managing Psoriasis in High Impact Sites is a Whole Different Ball Game"

Psound Bytes™

Psoriasis in high impact sites like the scalp, nails, genitals, palms, and soles is challenging. Hear views on living with such difficult to treat areas, and how appropriate treatments offer patient centered care from internationally recognized dermatologist Dr. Andrew Blauvelt, chair of the NPF Medical Board, patient advocates Brittany Murray and Crystal Gatlin, with moderator Corinne Rutkowski. This episode is provided with support from AbbVie. 

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Ep. 250 Ep. 250 "The Future of Psoriasis Care: Dr. Mona Shahriari Breaks Down New AAD Research & Personalized Treatments"

Psound Bytes™

Explore groundbreaking updates in psoriasis and psoriatic arthritis research from the 2025 AAD Annual Meeting with dermatologist Dr. Mona Shahriari. Join host Archie Franklin and renowned dermatologist Dr. Mona Shahriari as they unpack the latest research and clinical insights into managing psoriatic disease. This episode dives into head-to-head therapeutic trials, fast-acting treatments for high-impact areas like scalp and nails, and a preview of emerging oral biologics and GLP-1 weight management therapies. Dr. Shahriari discusses real-world challenges in treating psoriasis and psoriatic...

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Ep. 249 Ep. 249 "Facing Psoriasis Together and Finding Hope"

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Facing challenges presented by psoriasis can be an emotional roller coaster. From diagnosis, treatment choices, and the impact of bullying when a child has psoriasis can leave a parent feeling alone and helpless. Finding someone who's been on the same journey can be a benefit.  Hear how parents Jessie Houston, Nadya Helt, and Emma Rhodes with moderator Michel Tarabocchia found the help and hope they needed through the NPF One to One Program. 

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Ep. 248 Ep. 248 "How We Make an IMPACT in Psoriatic Disease"

Psound Bytes™

Making an impact as a volunteer can happen in many different ways. Hear what it means to volunteer and come together to attend the NPF IMPACT Volunteer Leadership Summit as 3 fabulous volunteers, John Romano, Alena Chapman, and NPF Board Member Chris Lindsay, share their experiences and how they fundraise to make a difference in the psoriatic disease community with Carol Osterhaus, NPF Senior Regional Development Manager for the Central Region. 

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Ep. 247 Ep. 247 "Psoriasis and Psoriatic Arthritis: More Than Skin and Joints"

Psound Bytes™

Having psoriasis may mean you're at risk for other diseases. Listen as moderators Alan Simmons and Kaleigh Welch explore cardiovascular disease, calcium build-up, NAFLD, sleep disorders, depression, anxiety, and the big question - does risk equal certainty with Dr. John Barbieri, Assistant Professor at Harvard Medical School, an investigator of the CP3 Study, and the Smart Phone Cognitive Behavioral Therapy Study. 

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Ep. 246 Ep. 246 "Speaking Up About Plaque Psoriasis," an Arcutis sponsored episode

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The journey from the first sign of plaque psoriasis to diagnosis and beyond is very familiar to Brandon, Christy and Daryl. Hear these real patients share the good and the bad of their plaque psoriasis journeys with moderator Max Blitstein. Listen as they discuss how they became empowered self advocates by speaking up for themselves with their healthcare provider. What differences did it make for them? Tune in to find out. This episode is sponsored by Arcutis Biotherapeutics, Inc. Please see and for the product mentioned in this podcast. 

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Ep. 245 Ep. 245 "Inverse Psoriasis Uncovered"

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Inverse psoriasis is more challenging to treat and to keep under control. Learn more as we uncover inverse psoriasis from what it is, typical symptoms and sites, other potential diseases, to being a risk factor for psoriatic arthritis, and what treatments are used either alone or in combination with dermatologist Dr. Jeffrey Cohen, Director, Psoriasis Treatment Program at Yale University School of Medicine and moderator Kaitlin Walden, RN. 

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More Episodes

Not sure what Minimal Disease Activity or MDA is and how it relates to psoriatic arthritis and your joints? Listen as rheumatologist Dr. Arthur Mandelin explains what MDA means.

Join hosts Jeff Brown and LB Herbert as they discuss minimal disease activity in psoriatic arthritis with nationally recognized rheumatologist Dr. Arthur Mandelin who identifies what it is, factors that influence achieving MDA, how long it takes to reach, and the impact on selection of treatments. Dr. Mandelin also addresses fatigue associated with inflammation, and what the future holds for minimal disease activity in psoriatic arthritis.

Whether you have psoriasis or psoriatic arthritis, this episode offers information to help you understand management goals set by your doctor and the importance of attaining minimal disease activity.

Timestamps:

  • (00:00) Intro to Psound Bytes & guest welcome rheumatologist Dr. Arthur Mandelin
  • (02:23) What is minimal disease activity (MDA)
  • (04:32) MDA in comparison to ACR response criteria
  • (07:36) Criteria for reaching MDA
  • (09:20) Positive and negative factors of MDA
  • (11:25) Importance of reaching MDA within a specific time frame
  • (17:34) Length of time to reach MDA
  • (18:48) Selection of treatment options and psoriatic arthritis domains
  • (23:51) Inflammation and fatigue
  • (26:59) A look at the future of minimal disease activity in psoriatic arthritis: Reaching ACR 90
  • (29:09) Advancements in psoriatic arthritis: Finding disease markers
  • (33:40 ) If you have psoriasis, be aware of your risk for psoriatic arthritis

4 Key Takeaways:

  • There are various ways to measure minimal disease activity in psoriatic arthritis to assess how the disease impacts quality of life.  
  • Attaining and keeping minimal disease activity low through use of different therapy options offers a chance for better bone and joint outcomes.
  • Advancements in psoriatic arthritis include attaining ACR90 and the potential for identifying key markers that make treatment selection more targeted and individualized.
  • Those who have psoriasis need to realize bone and joint pain, and swelling in the joints may be related to their psoriatic skin disease and seek appropriate help.

 Guest Bio:

Dr. Arthur Mandelin is an Associate Professor of Medicine at Northwestern University Feinberg School of Medicine and the Department of Medicine Division of Rheumatology. Dr. Mandelin launched Northwestern University’s first training program in musculoskeletal ultrasonography for rheumatology fellows. He is an active participant in the REASON Group which is a multi-center research collaboration devoted to using ultrasound guidance to obtain minimally invasive synovial tissue biopsies. Dr. Mandelin is a past member of the National Psoriasis Foundation’s Medical Board where he served on consensus panels for the development of a variety of practice guidelines.

 Resources Mentioned:

 Tags:

psoriasis, skin, psoriatic arthritis, minimal disease activity, ACR20, ACR50, ACR70, tender joints, bone erosion, joint swelling, enthesitis, inflammation, pain, fatigue, axial disease, spinal involvement, treatment, NSAIDS, biologics, personalized medicine, dermatology, National Psoriasis Foundation, AMP, Psound Bytes podcast, Soundbites podcast