REBEL Cast Ep127: From Debate to Data: Emerging Insights into RSI Induction with Ketamine vs Etomidate
Release Date: 04/18/2024
REBEL Cast - Street Medicine: Compassionate Care for the Unhoused
REBEL Cast
Introduction: In this episode of Rebel Cast, host Marco Propersi, along with co-hosts Steve Hockman and Kim Baldino, delve into the practice and importance of street medicine—the direct delivery of healthcare to homeless and unsheltered individuals. Special guests Dr. Jim O'Connell, a pioneer of street medicine, and Dr. Ed Egan, a recent street medicine fellowship graduate, share their experiences and insights on serving this vulnerable population. They discuss the origins, scope, and challenges of street medicine, the ethical dilemmas faced, and the profound impact of building trust and...
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REBEL Cast - Is Pip-Tazo Harming Sepsis Patients?
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In this episode of RebelCast, host Dr. Marco Propersi and guest Dr. Lynnsey Moss discuss the comparative study of piperacillin-tazobactam versus cefepime in the treatment of undifferentiated sepsis. They discuss a recent retrospective cohort study which examines 90-day mortality rates is sepsis patients treated with these antibiotics. The researchers explore the role of anti-anaerobic coverage and its potential for disrupting the gut microbiome. Key points discussed include the method of instrumental variable analysis, the validity of study findings, and a comparison with the ACORN trial. The...
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REBEL Core Cast 133.0 - TMJ Dislocation
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REBEL Cast - A Winning Hand in Cardiology: Queen of Hearts AI Model Enhances OMI Detection
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In this episode of Rebelcast, hosts Dr. Marco Propersi and Dr. Joe Bove discuss the Queen of Hearts, a groundbreaking AI tool changing the game in EKG interpretation for detecting occlusive myocardial infarctions. Joined by experts Dr. Pendell Meyers and Dr. Steve Smith, they delve into the nuances of OMI classification and highlight the advanced capabilities of this AI model. The conversation covers the development, validation, and implementation of the Queen of Hearts AI model, its potential impact on emergency medicine, and its future implications for medical education and practice.
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REBEL Core Cast 132.0 - Recent Onset AFib
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REBEL Core Cast 131.0 - Post-Dural Puncture Headache
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REBEL Core Cast 130.0 - Omphalitis
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REBEL Core Cast 129.0 - Gastric Lavage
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REBEL Core Cast 128.0 - Toxic Alcohols
REBEL Cast
We're back with our in house toxicologist Dr. Sanjay Mohan chatting about toxic alcohol ingestin.
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REBEL Core Cast 127.0 - Penetrating Neck Injuries
REBEL Cast
info_outlineResuscitationists have debated the choice of induction agents in rapid sequence intubation (RSI) for decades. Critics of etomidate will highlight its link to adrenal suppression in critically ill patients (Albert 2011), while critics of ketamine will highlight the higher incidence of post-intubation hypotension (Mohr 2020). Amidst the debate, the Ketased Trial (Jabre 2009), a large multicenter prospective, single-blind randomized clinical trial (RCT), reported no significant difference in SOFA scores or 28-day mortality between the two induction agents. However, the EvK trial (Matchett 2022) identified a statistically significant difference in 7-day mortality but not 28-day mortality in favor of ketamine. However, methodological concerns from the EvK Trial warrant a cautious interpretation of the data. In light of these and several other recent high-quality clinical trials comparing ketamine and etomidate, this meta-analysis aims to provide a point estimate of the mortality rate.